Brain

February 25, 2009 – (Bronx, NY) – Women who have more years of fertility (the time from first menstruation to menopause) have a lower risk of developing Parkinson's disease than women with fewer years, according to a large, new study by researchers at Albert Einstein College of Medicine of Yeshiva University.

Yale researchers have filled in a missing gap on the molecular road map of Alzheimer's disease.

In the Feb. 26 issue of the journal Nature, the Yale team reports that cellular prion proteins trigger the process by which amyloid-beta peptides block brain function in Alzheimer's patients.

The Declaration of Independence may proclaim that all men are created equal, but American whites tend to distribute their prejudice unequally toward certain members of minority groups, according to new research.

A series of six studies conducted by University of Washington and Michigan State University psychologists shows that whites react more negatively to racial minority individuals who strongly identify with their racial group than to racial minority individuals who weakly identify with their group.

Research on the sleeping brain has revealed some fascinating stage-dependent interactions between areas involved in formation and storage of long term memories. The study, published by Cell Press in the February 26th issue of the journal Neuron, may also provide a framework for further understanding the role of sleep in memory.

New research reveals a sophisticated brain mechanism that is critical for filtering out irrelevant signals during demanding cognitive tasks. The study, published by Cell Press in the February 26 issue of the journal Neuron, also provides some insight into how disruption of key inhibitory pathways may contribute to schizophrenia.

In the real world, odors don't happen one puff at a time. Animals move through, and subsequently distort, plumes of odor molecules that constantly drift, changing direction as the wind disperses them. Now, by exploring how animals smell odors under naturalistic conditions, Rockefeller University scientist Maria Neimark Geffen and her colleagues reveal that the brain encodes these swirling, and complex patterns of molecules using surprisingly little neural machinery. The findings suggest a new theory of how animals smell.

PASADENA, Calif.--By listening in on the chatter between neurons in various parts of the brain, researchers from the California Institute of Technology (Caltech) have taken steps toward fully understanding just how memories are formed, transferred, and ultimately stored in the brain--and how that process varies throughout the various stages of sleep.

Their findings, published in the February 26 issue of the journal Neuron, may someday even help scientists understand why dreams are so difficult to remember.

A new comprehensive review by researchers at the Montreal Neurological Institute (MNI), McGill University and the University of Cambridge, England provides vital insights into the neurological basis of addiction by investigating Parkinson's disease patients, who in some instances develop various addictions when undergoing medical treatment. The review, published in this week's (February 25) issue of the scientific journal Neuron, illustrates that persistently elevated levels of dopamine in the brain promote the development and maintenance of addictive behaviours.

PHILADELPHIA – Researchers at the University of Pennsylvania School of Medicine have unlocked the mystery of a puzzling human disease and gained insight into cardiovascular development, all thanks to a big-hearted fish.

WORCESTER, Mass. — Cutting edge science has finally put to rest a 90-year-old mystery that involved nobility, revolution, murder and the long-romanticized story of a child's escape from the firing squad.

A group of leading UK scientists and social scientists led by the ESRC Genomics Forum, based at the University of Edinburgh, calls for joined-up thinking on the emerging politics of plants.

Green is the new gold. The world is waking up to the potential of plants — from food to fuel, industrial feedstocks to carbon sinks, there is growing talk of plants replacing oil as the cornerstone of the global economy.

But such fame comes at a price.

Two compounds developed by Northwestern University chemists have been shown to be effective in pre-clinical trials in protecting against cerebral palsy, a condition caused by neurodegeneration that affects body movement and muscle coordination.

"The results were just stunning, absolutely amazing," said Richard B. Silverman, John Evans Professor of Chemistry in the Weinberg College of Arts and Sciences at Northwestern, who led the drug development effort. "There was a remarkable difference between animals treated with a small dose of one of our compounds and those that were not."

BUFFALO, N.Y. -- Capsaicin, the active ingredient in chili peppers, generally is viewed as an irritant that produces a burning sensation when applied to a sensitive area of the body, such as the cornea.

Paradoxically, the same compound also may reduce pain. Capsaicin creams are natural pain-relieving folk medicines, commonly found over the counter, and are effective for a variety of pain syndromes, from minor muscle or joint aches to those that are very difficult to treat, such as arthritis and neuropathic pain.

The recovery of some stroke victims, those who suffer brain haemorrhage, could be vastly improved if they were tested and treated for post-traumatic stress disorder, a distressing psychological condition more commonly known to affect soldiers who have fought in war zones.

Stem cells scientists at UCLA showed for the first time that human induced pluripotent stem (iPS) cells can be differentiated into electrically active motor neurons, a discovery that may aid in studying and treating neurological disorders.