Brain

Researchers have identified a key epigenetic mechanism in the brain that helps explain cocaine's addictiveness, according to research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

CAMBRIDGE, Mass., January 7, 2010 – Bioengineers have taken a small step toward improving physical recovery in stroke patients by showing that a key feature of how limb motion is encoded in the nervous system plays a crucial role in how new motor skills are learned.

Published in the November 25, 2009 issue of Neuron, a Harvard-based study about the neural learning elements responsible for motor learning may help scientists design rehabilitation protocols in which motor adaptation occurs more readily, potentially allowing for a more rapid recovery.

The laboratory of Dr. Frédéric Charron, in Montreal, made this discovery

A team of scientists from the University of Sheffield have scooped an international award in recognition of their work on an innovative device which will make the production of alternative biofuels more energy efficient.

Using laboratory mice that had been bred to have brain changes similar to Alzheimer's disease, scientists were able to reduce two characteristic features of the disease by modifying the mice's immune systems with a special peptide (MOG45D) related to the myelin sheath that insulates nerve cells and nerve fibers. As a result, anti-inflammatory cells were recruited from the blood into the brain, dampening the local inflammatory response.

CAMBRIDGE, Mass. -- In the early stages of Alzheimer's disease, patients typically suffer a major loss of the brain connections necessary for memory and information processing. Now, a combination of nutrients that was developed at MIT has shown the potential to improve memory in Alzheimer's patients by stimulating growth of new brain connections.

Tampa, FL (Jan. 6, 2010) – The millions of people who spend hours every day on a cell phone may have a new excuse for yakking. A surprising new study in mice provides the first evidence that long-term exposure to electromagnetic waves associated with cell phone use may actually protect against, and even reverse, Alzheimer's disease. The study, led by University of South Florida researchers at the Florida Alzheimer's Disease Research Center (ADRC), was published today in the Journal of Alzheimer's Disease.

ST. PAUL, Minn. – A new type of brain scan, called diffusion tensor imaging (DTI), appears to be better at detecting whether a person with memory loss might have brain changes of Alzheimer's disease, according to a new study published in the January 6, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Neuroscientists at the Massachusetts Institute of Technology have developed a powerful new class of tools to reversibly shut down brain activity using different colors of light. When targeted to specific neurons, they could potentially lead to new treatments for abnormal brain activity associated with disorders including chronic pain, epilepsy, brain injury and Parkinson's disease.

The space within reach of our hands — where actions such as grasping and touching occur — is known as the "action space." Research has shown that visual information in this area is organized in hand-centered coordinates — in other words, the representation of objects in the human brain depends on their physical location with respect to the hand.

CAMBRIDGE, Mass. - Neuroscientists at MIT have developed a powerful new class of tools to reversibly shut down brain activity using different colors of light. When targeted to specific neurons, these tools could potentially lead to new treatments for the abnormal brain activity associated with disorders such as chronic pain, epilepsy, brain injury, and Parkinson's disease.

ANN ARBOR, Mich.---Black men are over-diagnosed with schizophrenia at least five times higher than any other group--a trend that dates back to the 1960s, according to new University of Michigan research.

Race-based misdiagnosis emerged in the context of the civil rights era of the 1960s and 1970s, when activism became equated with mental illness, says Jonathan Metzl, an associate professor of psychiatry and women's studies.

North Grafton, Mass., January 6, 2009 – A canine chromosome 7 locus that confers a high risk of compulsive disorder susceptibility has been identified through a collaboration between the Behavior Service at the Cummings School of Veterinary Medicine, the Program in Medical Genetics at the University of Massachusetts Medical School and the Broad Institute at the Massachusetts Institute of Technology. The findings are published in the January 2010 edition of Molecular Psychiatry.

Researchers from the University of Minnesota Medical School discovered that light from an ultraviolet diode (UV LED) reduced "seizure-like" activity in a rat epilepsy model. During the study, UV light released gamma aminobutyric acid (GABA) from the "caged" compound carbonyl amino butanoic acid (BC204). GABA then decreased the abnormal electrical activity in the CA1 area of the brain. Results of this study have considerable potential in treating focal epilepsy in humans.

WASHINGTON – Girls around the world are not worse at math than boys, even though boys are more confident in their math abilities, and girls from countries where gender equity is more prevalent are more likely to perform better on mathematics assessment tests, according to a new analysis of international research.