GLENDALE, Arizona (November 30, 2010)—What are the earliest brain changes associated with the risk of developing Alzheimer's disease? A scientific report published in the October Journal of Alzheimer's Disease finds reduced activity of an energy-generating enzyme in deceased young adult brain donors who carry a common genetic risk factor for Alzheimer's disease—before the protein changes or microscopic abnormalities commonly associated with the disease and almost five decades before the age at which they might have developed memory and thinking problems.
Brain
Our brains are packed with cholesterol, almost all of which has to be produced within the brain itself, where it is critical for normal brain functions. Now, a new study in the December Cell Metabolism, a Cell Press publication, reveals how that critical cholesterol synthesis in the brain is derailed in mice with diabetes.
The findings offer a new explanation for the neurologic and cerebral complications that come with diabetes, including cognitive dysfunction, depression, and an increased risk of Alzheimer's disease, according to the researchers.
BOSTON – November 30, 2010 – The brain contains more cholesterol than any other organ in the body, has to produce its own cholesterol and won't function normally if it doesn't churn out enough. Defects in cholesterol metabolism have been linked with Alzheimer's disease and other neurodegenerative conditions. Now researchers at Joslin Diabetes Center have discovered that diabetes can affect how much cholesterol the brain can make.
BOSTON – November 30, 2010 – The brain contains more cholesterol than any other organ in the body, has to produce its own cholesterol and won't function normally if it doesn't churn out enough. Defects in cholesterol metabolism have been linked with Alzheimer's disease and other neurodegenerative conditions. Now researchers at Joslin Diabetes Center have discovered that diabetes can affect how much cholesterol the brain can make.
An Italian research team confirmed that the scoring system for Wilson's disease (WD) provides good diagnostic accuracy with 93% positive and 92% negative predictive values, respectively in children with mild liver disease. In asymptomatic children, a urinary copper excretion above 40 μg/24 hours was suggestive of WD, however the penicillamine challenge test (PCT) did not provide an accurate diagnosis in this patient subset.
New research using a world leading motorcycle simulator to analyse rider behaviour has proved that safer doesn't necessarily mean slower and that formal advanced training for bikers can demonstrate improved safety on our roads.
The study was carried out by researchers at The University of Nottingham's Centre for Motorcycle Ergonomics & Rider Human Factors. The preliminary results of the research are published today by the Institute of Advanced Motorists (IAM) which funded the research.
Society appreciates powerful individuals' efforts, regardless of them having success or failing. Conversely, when someone without such power fails, their failure is attributed to their "unability to carry out their tasks", and their efforts are not appreciated. In other words: individuals' personal power clearly affects how others perceive their success or failures.
BEER-SHEVA, ISRAEL, November 30, 2010 -- "Good looks" are only sometimes a positive factor in consideration for a job, according to new research from Ben-Gurion University of the Negev (BGU). In the new working paper, "Are Good-Looking People More Employable?" two economics researchers from BGU prove that a double standard exists between good looks as a positive factor in men and women.
A national conversation continues about the best ways to improve both the quality of medical care and to contain costs. So far, developing quality measurements has focused on primary care or highly prevalent, chronic conditions such as asthma and diabetes. But what about brain disorders? To date, the number of measures that apply to neurologic care has been limited.
CHICAGO – Using functional magnetic resonance imaging (fMRI), researchers have captured pictures of the brain while patients experienced a pain stimulus with and without acupuncture to determine acupuncture's effect on how the brain processes pain. Results of the study, which the researchers say suggest the effectiveness of acupuncture, were presented today at the annual meeting of the Radiological Society of North America (RSNA).
ST. PAUL, Minn. – The American Academy of Neurology has developed a new tool to help doctors gauge how well they are caring for people with Parkinson's disease. The new quality measures are published in the November 30, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers have found that the naturally-occurring hormone and neurotransmitter oxytocin intensifies men's memories of their mother's affections during childhood. The study was published today in Proceedings of the National Academy of Sciences.
When crossing a street, we look to the left and right for cars and stay put on the sidewalk if we see a car close enough and traveling fast enough to hit us before we're able to reach the other side. It's an almost automatic decision, as though we instinctively know how to keep ourselves safe.
How do individuals often cope with reentry from prison to society?
Too frequently with avoidance, says Lindsay Phillips, assistant professor of psychology at Albright College in Reading, Pa. and author of the forthcoming paper, "Prison to Society: A Mixed Methods Analysis of Coping with Reentry," to be published by the International Journal of Offender Therapy and Comparative Criminology.
Tel Aviv - In the human brain, mechanical stress -- the amount of pressure applied to a particular area -- requires a delicate balance. Just the right force keeps neurons together and functioning as a system within the body, and proper nerve function is dependent on this tension.