Brain

For Immediate Release – February 8, 2011 - (Toronto) – A new study from the Centre for Addiction and Mental Health (CAMH) has found evidence suggesting that a variation of a specific gene may play a role in late-onset Alzheimer's, the disease which accounts for over 90% of Alzheimer's cases. This innovative study has combined genetics and brain imaging to determine who may be at risk for developing late-onset Alzheimer's disease long before symptoms appear.

Much of the devastation of stroke and head trauma is due to damage caused the overproduction of a substance in the brain called glutamate. Preventing this damage has been impossible, until now, as many drugs don't cross the so-called blood-brain barrier, and those that do often don't work as intended. But a method originally devised at the Weizmann Institute of Science may, in the future, offer a way to avert such glutamate-induced harm.

Like listeners adjusting a high-tech radio, scientists at Washington University School of Medicine in St. Louis have tuned in to precise frequencies of brain activity to unleash new insights into how the brain works.

"Analysis of brain function normally focuses on where brain activity happens and when," says Eric C. Leuthardt, MD. "What we've found is that the wavelength of the activity provides a third major branch of understanding brain physiology."

Drinking excess alcohol during pregnancy can cause fetal alcohol syndrome (FAS) due to the damaging effects of alcohol on a developing baby's brain. Despite its harmful effects, pregnant mothers continue to drink alcohol – up to 3 in every 1000 babies are born with FAS, which causes intellectual disabilities, behavioural problems, growth defects and abnormal facial features. How alcohol causes these effects is unclear, but researching the problem is difficult because of ethical barriers to studying human fetuses.

A diet, high in fats, sugars, and processed foods in early childhood may lower IQ, while a diet packed full of vitamins and nutrients may do the opposite, suggests research published online in the Journal of Epidemiology and Community Health.

The authors base their findings on participants in the Avon Longitudinal Study of Parents and Children (ALSPAC), which is tracking the long term health and wellbeing of around 14,000 children born in 1991 and 1992.

ANN ARBOR, Mich. — Numerous studies have shown that the brain molecule neuropeptide Y (NPY) helps to restore calm after stressful events. A team of University of Michigan-led researchers has now found that people whose genes predispose them to produce lower levels of NPY are more responsive to negative stimuli in key brain circuits related to emotion – and are therefore less resilient in the face of stress and may be at higher risk for developing a major depressive disorder.

ANN ARBOR, Mich. — As loved ones with dementia disappear into symptoms of aggression, agitation or delusions, families are left with few good medical solutions. A new generation of antipsychotic medications gained popularly in the 1990s because they avoided side effects such as Parkinson's syndrome associated with conventional antipsychotic medications used to treat dementia.

Cannabis use appears to be associated with an earlier onset of psychotic illness, according to a meta-analysis of previously published studies posted online today that will appear in the June print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Patients with schizophrenia who take antipsychotic medications appear to lose a small but measurable amount of brain tissue over time, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Language may play an important role in learning the meanings of numbers, scholars at the University of Chicago report.

A study based on research on deaf people in Nicaragua who never learned formal sign language showed that people who communicate using self-developed gestures, called homesigns, were unable to comprehend the value of numbers greater than three because they had not learned a language containing symbols used for counting.

WASHINGTON — When people think unpleasant events are over, they remember them as being less painful or annoying than when they expect them to happen again, pointing to the power of expectation to help people brace for the worst, according to studies published by the American Psychological Association.

In a series of eight studies exposing people to annoying noise, subjecting them to tedious computer tasks, or asking them about menstrual pain, participants recalled such events as being significantly more negative if they expected them to happen again soon.

Arnhem, The Netherlands, 7 February 2011 -- In the February 2011 issue of European Urology, Jean-Nicolas Cornu and colleagues reported the evaluation of the efficacy of prostate cancer (PCa) detection by trained dogs on human urine samples.

PHILADELPHIA — The more allergies one has, the lower the risk of developing low- and high-grade glioma, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Binge drinking is often considered to be a problem of towns and cities but new research published in BioMed Central's open access journal BMC Public Health shows that binge drinking in rural areas is more of a problem than previously thought.

NEW YORK (February 4, 2011) – Researchers at the NYU Child Study Center demonstrated that a brief program for families of Pre-Kindergarten students attending schools in disadvantaged urban communities improved children's behavior at school. The study, called "Promoting effective parenting practices and preventing child behavior problems in school among ethnically diverse families from underserved, urban communities," was published in the February 2011 issue of Child Development.