Brain

A mother's iron deficiency early in pregnancy may have a profound and long-lasting effect on the brain development of the child, even if the lack of iron is not enough to cause severe anemia, according to a University of Rochester Medical Center study published in the scientific journal PLoS One.

The results are important because obstetricians might not notice or treat mild or moderate iron deficiency, and therefore the study authors believe their research underscores the need for monitoring a pregnant woman's iron status beyond anemia.

Patrick Stroman's work mapping the function and information processing of the spinal cord could improve treatment for spinal cord injuries.

"Basic physiology books describe the spinal cord as a relay system, but it's part of the central nervous system and processes information just like parts of the brain do," explains Dr. Stroman, director of the Queen's MRI Facility and Canada Research Chair in Imaging Physics.

We hold many beliefs about memory—for instance, if you study more, you learn more. We are also constantly making judgments about particular instances of learning and remembering—I'll never forget this party! That was easy to understand. I'll ace it on the test.

But do beliefs influence judgments, and how do judgments affect memory performance? "There's a disconnect among beliefs, judgments, and actual memory," says Williams College psychologist Nate Kornell. Ask people to predict how or what they will learn and "in many situations, they do a breathtakingly bad job."

LA JOLLA, CA—A key question in protein biochemistry is how proteins recognize "correct" interaction partners in a sea of cellular factors. Nowhere is that more critical to know than in the brain, where interactions governing channel protein activity can alter an organism's behavior. A team of biologists at the Salk Institute for Biological Studies has recently deciphered a molecular code that regulates availability of a brain channel that modulates neuronal excitability, a discovery that might aid efforts to treat drug addiction and mental disorders.

Philadelphia, PA, 22 March, 2011 - The hippocampus, a brain region implicated in memory and interpreting environmental contexts, has been the focus of a controversy in posttraumatic stress disorder (PTSD).

Toddlers who played with a limited number of toys showed more improvement in their communication skills following parent-guided treatment than those receiving other community-based treatments.

The report is the first to examine this autism treatment – called Hanen's More Than Words – for children younger than 2 showing early signs of an autism spectrum disorder. Caught early enough and treated with the right behavioral therapy, autism symptoms can improve dramatically.

The paper appears online March 22 in the Journal of Child Psychology and Psychiatry.

Although universal newborn hearing screening programs appear to identify children with hearing loss at a younger age, nearly one-third of pediatric cochlear implant recipients pass newborn screening only to be diagnosed later in infancy or early childhood, according to a report in the March issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

A paper announcing a breakthrough discovery in the fight against Niemann-Pick Type C, coauthored by Olaf Wiest and Paul Helquist of the University of Notre Dame's Department Chemistry & Biochemistry and Frederick Maxfield, Chair of Biochemistry at Cornell University Weill College of Medicine, appears in the Proceedings of the National Academy of Sciences this week. The paper shows how use of a histone deacetylase inhibitor correct the damage done by the genetic disorder and allowed once-diseased cells to function normally.

COLUMBUS, Ohio – Saying a prayer may help many people feel less angry and behave less aggressively after someone has left them fuming, new research suggests.

A series of studies showed that people who were provoked by insulting comments from a stranger showed less anger and aggression soon afterwards if they prayed for another person in the meantime.

Washington, D.C., 21 March, 2011 – Alcohol use during pregnancy is common and is associated with significant threats to the health and development of exposed offspring. Despite warnings from the Surgeon General to limit alcohol use if pregnant or contemplating pregnancy, a recent survey by the National Birth Defects Prevention Study(1) found that nearly one-third of women drank alcohol at some time during their pregnancy, with one-fourth of the women surveyed having drunk during the first trimester.

Coupling an electronic prescription drug ordering system with a computerized method for reporting adverse events can dramatically reduce the number of medication errors in a hospital's psychiatric unit, suggests new Johns Hopkins research.

DURHAM, N.C. – You may remember the color of your loved one's eyes for years. But how?

Scientists believe that long-term potentiation (LTP) – the long-lasting increase of signals across a connection between brain cells -- underlies our ability to remember over time and to learn, but how that happens is a central question in neuroscience.

There are potential legal ramifications for physicians of patients who drive with cognitive impairment, according to a study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.

The team of Prof. Dr. Stefan Herlitze, the Chair of the Department of Zoology and Neurobiology at RUB, showed that the diseases broke out in mice if, a week after birth, they eliminated a particular protein in the cerebellum which regulates the influx of ions into nerve cells. "It's the first time that we have gained an insight into the origin of these diseases" said Prof. Herlitze. "We can now start conducting research to develop new therapeutic approaches."

When Geoffrey Murphy, Ph.D., talks about plastic structures, he's not talking about the same thing as Mr. McGuire in The Graduate. To Murphy, an associate professor of molecular and integrative physiology at the University of Michigan Medical School, plasticity refers to the brain's ability to change as we learn.