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What The Article Says: This JAMA Insights review from Centers for Disease Control and Prevention COVID-19 Response team members presents data on the number of long-term care facilities and the numbers of residents and staff of those facilities who received first-dose vaccination through mid-January under the agency's public-private partnership with CVS, Walgreens and Managed Health Care Associates.
Authors: Radhika Gharpure, D.V.M., M.P.H., of the COVID-19 Response at the CDC, is the corresponding author.
The steadily increasing prevalence and high costs of treating chronic joint pain worldwide poses a challenge for healthcare systems and healthcare payers.
CLEVELAND, Ohio - Researchers at University Hospitals Rainbow Babies & Children's Hospital (UH Rainbow) published new findings today that wearing a face mask - either a cloth mask or a surgical mask - did not impair the ability of subjects to get air in and out of their bodies.
A study aiming to develop a new therapeutic technique could bring a revolution in our approach to treating rare, fatal Sanfilippo syndrome, a disorder that affects children as young as 2 years old and leads to childhood dementia and premature death.
"We are using a combination of gene therapy, stem cells and small molecules to restore metabolic defects in the patient's brain cells" says Dr. Alexey Pshezhetsky, Professor at CHU Ste-Justine and lead GlycoNet Investigator on this project. "First results in the mouse models of the disease are very encouraging."
DALLAS - Feb. 24, 2021 - Using machine learning tools to analyze hundreds of proteins, UT Southwestern researchers have identified a group of biomarkers in blood that could lead to an earlier diagnosis of children with autism spectrum disorder (ASD) and, in turn, more effective therapies sooner.
The identification of nine serum proteins that strongly predict ASD were reported in a study published today by PLOS ONE.
In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found.
BOSTON - Swelling of lymph nodes in the armpit area is a normal response to COVID-19 vaccinations, but when they are seen on mammograms, they can be mistaken for nodes that are swollen because of cancer. In some cases, the nodes are biopsied to confirm they are not cancer. To avoid confusion by patients and their providers, and to avoid delays in either vaccinations or recommended mammograms through the pandemic, radiologists at Massachusetts General Hospital (MGH) have published an approach to manage what is expected to be a fairly common occurrence as vaccination programs ramp up.
Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Professionals, estimates that 858,000 Americans use opioids such as tramadol and oxycodone for their knee pain, equating to $14 billion in lifetime opioid-related societal costs, or nearly $0.5 billion annually.
Slight differences in clinical features can help physicians distinguish between two rare but similar forms of autoimmune brain inflammation in children, a new study by UT Southwestern scientists suggests. The findings, published online in Pediatric Neurology, could provide patients and their families with a better prognosis and the potential to target treatments specific to each condition in the future.
This study, published recently in the international journal Insects, was conducted by researchers from the University of Granada, the Doñana Biological Station, and the Biomedical Research Networking Centre for Epidemiology and Public Health (CIBERESP)
WHAT:
Inflammatory lung diseases such as asthma, COPD and, most recently, COVID-19, have proven difficult to treat. Current therapies reduce symptoms and do little to stop such diseases from continuing to damage the lungs. Much research into treating chronic inflammatory diseases has focused on blocking chemicals called cytokines, which trigger cascades of molecular events that fuel damaging inflammation.
Neuroblastoma is a cancer that develops in nerve tissue, most commonly in the glands around the kidneys. The gene MYCN is overexpressed in 20-25% of neuroblastoma, and MYCN-amplified neuroblastoma contributes to a considerable percentage of pediatric cancer-related deaths.
If Affordable Care Act protections for pre-existing condition coverage are no longer available, the coronavirus pandemic would leave many Americans - a disproportionate number of whom are people of color - without health insurance, a new Oregon Health & Science University study indicates.
UCLA RESEARCH BRIEF
Enrique Rivero