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Expectant women are more likely to give birth early if they have high blood levels of a chemical used in flame retardants compared with those who have limited exposure, a new study finds.
A University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2 diabetes to identify a small molecule that may help regulate cholesterol levels in the brain, making it a potential new therapeutic target for Alzheimer's disease.
March 23, 2021-- A new study published online in the Annals of the American Thoracic Society examines if the source of physician payment for a medical opinion influences whether the physician finds that a coal miner has black lung disease. The study is the first to look at this relationship in the workers' compensation process.
New clues to a long-pursued drug target in cancer may reside within immune cells, researchers at the University of Michigan Rogel Cancer Center have discovered.
The findings, which appear in Nature Immunology, not only shed new light on cancer immunology, they also suggest clinical trials related to this key target -- an interaction that destabilizes the important p53 tumor suppressor protein -- may unnecessarily be excluding a large number of patients.
The researchers are optimistic that the findings could help make immunotherapy treatment more effective against cancer.
More than half of the opioid tablets prescribed for patients who underwent orthopaedic or urologic procedures went unused in a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania. Using an automated text messaging system that regularly checked in with patients on their pain and opioid use, the study also showed that most opioids are taken within the first few days following a procedure and may not be necessary to manage pain even just a week following a procedure. The study was published today in JAMA Network Open.
BOSTON - In the largest study of its kind to date, researchers at Massachusetts General Hospital, Brigham and Women's Hospital and the Ragon Institute of MGH, MIT and Harvard have found the new mRNA COVID-19 vaccines to be highly effective in producing antibodies against the SARS-CoV-2 virus in pregnant and lactating women. They also demonstrated the vaccines confer protective immunity to newborns through breastmilk and the placenta.
People who are physically active on a regular basis recover better after surgery for colorectal cancer. However, starting to exercise only after the diagnosis is a fact had no effect on recovery, a University of Gothenburg thesis shows.
In working on his thesis, Aron Onerup, who obtained his doctorate in surgery at the University's Sahlgrenska Academy and is now a specialist doctor at Sahlgrenska University Hospital, carried out an observational study of 115 patients diagnosed with colorectal cancer.
Oncotarget published "Phase 1 study of Z-Endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors" which reported that Z-endoxifen administration was anticipated to bypass these variations, increasing active drug levels, and potentially benefiting patients responding sub-optimally to tamoxifen.
HOUSTON, TX - March 25, 2021 - Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections. HSCs can either duplicate to produce more stem cell progeny or differentiate to produce distinct immune cell lineages, an extremely critical decision that ensures that the body achieves the fine balance between having enough immune cells to fight invaders while still retaining enough HSCs to maintain future blood production.
NEW YORK, NY--Treatments for a rare retinal disease may be on the horizon after a new study has identified gene variants that cause a metabolic deficiency in the eye.
The disease, macular telangiectasia type 2 (MacTel), has been a research focus of Rando Allikmets, PhD, a pioneer in the genetics of eye diseases, for nearly 15 years. MacTel occurs in approximately 1 in 5,000 adults over age 40 and slowly causes a significant loss of central vision, which can impair driving, reading, and other activities.
GALVESTON, Texas - A new study conducted at the Galveston National Laboratory at the The University of Texas Medical Branch at Galveston (UTMB) has shown substantial benefit to combining monoclonal antibodies and the antiviral remdesivir against advanced Marburg virus. The study was published today in Nature Communications.
Today, Cochrane, a global independent network that gathers and summarizes the best evidence from research to help informed health decision-making, publishes an updated systematic review assessing rapid tests for the detection of SARS-CoV-2 infection (COVID-19). The review shows that rapid antigen tests are better at correctly identifying cases of COVID-19 in people with symptoms than in people without symptoms. There are large differences in the accuracy of different brands of test, with very few meeting the World Health Organization (WHO) minimum acceptable performance standards.
March 24, 2021 - For premature infants who can't breastfeed on their own, "mother's own milk" (MOM) is by far the best nutrition. There's an urgent need for effective ways to increase the relatively low rates of MOM feeding for preterm infants born to Black and Hispanic mothers.
HOUSTON - (Mar 24, 2021) -The mammalian center for learning and memory, hippocampus, has a remarkable capacity to generate new neurons throughout life. Newborn neurons are produced by neural stem cells (NSCs) and they are crucial for forming neural circuits required for learning and memory, and mood control. During aging, the number of NSCs declines, leading to decreased neurogenesis and age-associated cognitive decline, anxiety, and depression.
Probiotics -- those bacteria that are good for your digestive tract -- are short-lived, rarely taking residence or colonizing the gut. But a new study from researchers at the University of California, Davis, finds that in breast milk-fed babies given the probiotic B. infantis, the probiotic will persist in the baby's gut for up to one year and play a valuable role in a healthy digestive system. The study was published in the journal Pediatric Research.