Body

Heart researchers at the Center for Translational Medicine at Jefferson Medical College have used gene therapy to reverse heart failure in animals. In addition, they found that this gene therapy strategy had "unique and additive effects" to currently used, standard heart failure drugs called beta-blockers.

Call it the cellular equivalent of big glasses, a funny nose and a fake mustache.

Bone marrow stem cells attracted to the site of a cancerous growth frequently take on the outward appearance of the malignant cells around them, University of Florida researchers report in a paper to be published in the August issue of Stem Cells.

Long before animals with limbs (tetrapods) came onto the scene about 365 million years ago, fish already possessed the genes associated with helping to grow hands and feet (autopods) report University of Chicago researchers.Paddlefish fins exhibit a unique pattern of Hox expression previously thought present only in the developing hands and feet of land vertebrates (tetrapods). This result supports the notion that fossil fish already possessed the genetic toolkit needed to evolve hands, feet, fingers and toes.

Could the food we eat be contributing to the continuing rise of antibiotic-resistant infections? Harmless and even beneficial bacteria that exist in our food supply may also be carrying genes that code for antibiotic resistance. Once in our bodies, could they transmit the resistance genes to disease-causing bacteria?

Circadian clocks regulate the timing of biological functions in almost all higher organisms. Anyone who has flown through several time zones knows the jet lag that can result when this timing is disrupted.

Now, new research by Cornell and Dartmouth researchers explains the biological mechanism behind how circadian clocks sense light through a process that transfers energy from light to chemical reactions in cells.

Leave it to white Canadians to tell African-Americans how they feel about people with health problems.

A study by the University of Alberta, published in the Journal of Clinical Epidemiology, says African Americans appear to perceive people with extreme health problems as less productive or valuable

The study examined the differences in preferences for the EQ-5D health states among African Americans, Hispanics, and other races living in the United States.

Two new papers demonstrate that adolescent female sheep that become pregnant before they have achieved their full growth may not be able to supply enough nourishment for their fetuses to develop without physical deficits.

These studies may also have implications for managing pregnancies of adolescent human females, who, in increasing numbers worldwide, are bearing offspring before they have finished growing.

A new study in the May issue of the Journal of Wildlife Management reports that scientists from the New York State Museum, Wildlife Conservation Society and other groups have teamed up with the New York State Department of Criminal Justice to developed a new technique that uses fingerprints to track the fisher--an elusive member of the weasel family, and the only carnivore species known to have unique fingerprints.Scientists recovered this camera trap photo of a fisher, an elusive member of the weasel family. Credit: Wildlife Conservation Society

In the tropics, even the birds know how to relax better than those in the north. Tropical birds expend less energy at rest than do birds living in more northern climates, according to a study published online this week in the Proceedings of the National Academy of Sciences.Take a tip from tropical birds. Enjoy life a little.

Thymic nurse cells were given their name because of their intimate relationship with developing T cells (thymocytes) in the thymus.

Regulatory oversight of nanotechnology is urgently needed and the Environmental Protection Agency (EPA) should act now, reports a new study released today. In EPA and Nanotechnology: Oversight for the 21st Century, former EPA assistant administrator for policy, planning and evaluation, J. Clarence (Terry) Davies, provides a roadmap for a new EPA to better handle the challenges of nanotechnology.

Nature, through the trial and error of evolution, has discovered a vast diversity of life from what can only presumed to have been a primordial pool of building blocks.

Not only does exercise make most people feel better and perform physical tasks better, it now appears that exercise – specifically, resistance training -- actually rejuvenates muscle tissue in healthy senior citizens.

A recent study, co-led by Simon Melov and Mark Tarnopolsky, involved before and after analysis of gene expression profiles in tissue samples taken from 25 healthy older men and women who underwent six months of twice weekly resistance training, compared to a similar analysis of tissue samples taken from younger healthy men and women.

Scientists have made a breakthrough in understanding how cancers spread in what could lead to new ways of beating the disease.

The University of Manchester study used embryonic stem (ES) cells to investigate how some tumours are able to migrate to other parts of the body, which makes the treatment of cancer much more difficult.

Dr Chris Ward, in the University’s Faculty of Medical and Human Sciences, studied a crucial change that makes cancer cells able to start moving and spread into other tissues.

Pancreatic cancer is among the deadliest of today's cancers due to limited tools for early diagnosis and few effective treatments. Research presented today takes a closer look at pancreatic cancer and the conditions that may lead to it, such as chronic pancreatitis, to evaluate the progress made to date, as well as the promising new applications of technology that will improve survival rates in the coming years. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.