A drug under study to treat various cancers selectively kills cancer cells because of its affinity for a modified version of a critical heat shock protein they contain, researchers have found.
They found in cancer a modified version of heat shock protein 90, or hsp90, which like most heat shock proteins, promotes cell survival.
Maybe not, but they get hot flashes related to genital changes.
Men who have undergone chemical castration for conditions such as prostate cancer experience hot flashes similar to those experienced by menopausal women, says a new study in Psychophysiology.
Using a technique called sternal skin conductance, doctors were able to positively identify hot flashes in males, a positive step toward providing therapy for those patients in need.
Research finds calorie-dense dessert recipes printed in major newspapers across the country may be contributing to obesity in large cities. The study, conducted by researchers at Marshfield Clinic Research Foundation, Marshfield, Wis., is published in the latest issue of the Wisconsin Medical Journal (Volume 106, No. 2).
The regions studied were in the West (Los Angeles, Denver, Portland), Midwest (Milwaukee, Detroit, Kansas City), South (Washington D.C., Dallas, Jacksonville) and the Northeast (New York, Philadelphia, Boston).
Immune cells that are the body’s front-line defense don’t necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan scientists describe their findings that bacteria can barge inside these guard cells and independently initiate a powerful immune response.
Researchers have successfully applied X-ray scattering techniques to determine how dissolved metal ions interact in solution.
Dutch researcher Laura Brandán Briones, that's who.
She improved both the tests and the method to determine the reliability of the tests. This means, for example, that washing machines and coffee machines can be tested far better before they are launched on the market.
Brandán Briones made several considerable improvements. First of all she made it possible to include the factor 'time' in the testing. Not only can it be determined if coffee actually comes out of the machine but also how long that takes.
Human bone marrow has been used to create early-stage sperm cells for the first time, a scientific step forward that will help researchers understand more about how sperm cells are created.
People who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things.
However, individuals with just a single mutant copy of one of these genes are also at increased risk of developing cancer. This occurs when the remaining "good" copy of the gene becomes mutated in a specific cell type, allowing that cell type to form a tumor.
Unique three-dimensional solar cells that capture nearly all of the light that strikes them could boost the efficiency of photovoltaic (PV) systems while reducing their size, weight and mechanical complexity.
Through photosynthesis, green plants and cyanobacteria are able to transfer sunlight energy to molecular reaction centers for conversion into chemical energy with nearly 100-percent efficiency. Speed is the key - the transfer of the solar energy takes place almost instantaneously so little energy is wasted as heat.
Researchers from Harvard Medical School and Beth Israel Deaconess Medical Center have captured and sequenced tiny pieces of collagen protein from a 68 million-year-old Tyrannosaurus rex. The protein fragments—seven in all—appear to most closely match amino acid sequences found in collagen of present day chickens.
The results of a new study suggest that bacteria that cause diseases like bubonic plague and serious gastric illness can turn the genes that make them infectious on or off.
Knowing how disease-causing bacteria, like Yersinia pestis and E. coli, do this may one day help scientists create drugs that control the expression of these genes, thereby making the bacteria harmless, said Vladimir Svetlov, a study co-author and a research associate in microbiology at Ohio State University. The findings appear in the April 13 issue of the journal Molecular Cell.
A new technology developed at the University of Toronto is revealing biochemical processes responsible for diseases such as cystic fibrosis and could one day pave the way for pharmaceutical applications.
The "iMYTH-system" shows a positive readout of our iMYTH sytem. If two proteins interact in iMYTH system the yeast cell will stain blue. Credit: Staglar lab
A disturbingly high prevalence of self-reported drinking and driving has been found among Spanish health professionals. Published today in BMC Public Health, the study reveals that Spanish doctors and nurses are self-reporting drink driving at even higher rates than other university graduates.
The powerful earthquake struck suddenly, shaking the seven-story building so hard it bent, cracked and swayed in response.