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New knowledge points to the fact that a genetically induced lack of filaggrin, a key protein of the skin barrier, plays a decisive role in the origin of allergies. In a large study on more than 3000 school-children scientists of the Helmholtz Zentrum München and the Technische Universität München found that about 8% of the German population carry variations of the filaggrin gene, which raise the risk to develop atopic dermatitis more than threefold. In addition, these genetic variations predispose to hay fever and asthma in those with atopic dermatitis.

NEW YORK (July 31, 2008) -- With the recent endorsement by the World Health Organization (WHO) and scientists worldwide of adult male circumcision as an important strategy for HIV prevention, there is increased urgency to develop safe and cost-effective circumcision services. This is especially the case in Africa where HIV/AIDS continues to spread at an epidemic rate.

This release is also available in German.

July 30, 2008. A scientific project funded by the BBVA Foundation and conducted by a team from the Spanish Council for Scientific Research (CSIC) explored around 100 kilometers of practically uncharted Atlantic beach in the north of Colombia and south of Panama between the years 2006 and 2007. In the course of their work, they came across extensive nesting grounds that bring new hope for the survival of the leatherback turtle.

(Boston) -- In the history of science and technology, there is an infrequent combination of empirical discoveries, theories and technology developments converge that make it possible to recognize a new discipline. Past examples include marine biology, biomechanics and astrobiology with more recent developments of nanotechnology and bioinformatics – all disciplines that are now well established in the lexicon of modern science and technology.

BOSTON — Working overtime has a disproportionate impact on women in dual-earner households, exacerbating gender inequality and supporting the "separate sphere" phenomenon in which men are the breadwinners while women tend to the home, according to research to be presented at the annual meeting of the American Sociological Association.

The standard regimens to treat tuberculosis (TB) are inadequate in countries with high rates of multi-drug resistant (MDR) TB. In countries with high rates of MDR-TB, patients are nearly twice as likely to fail their initial treatment than those in countries with low rates, according to a new analysis of World Health Organization (WHO) data. This finding suggests strongly that current TB treatment regimens need to updated and revised to address the shifting landscape of public health in the face of MDR-TB.

A new study by researchers at The University of Texas Medical School at Houston could help experts better decide whether to continue the current practice of retesting women during their second pregnancies for a common bacterial infection if they had tested positive for the infection previously.

WESTCHESTER, Ill. – A study in the August 1 issue of the journal Sleep shows that people with severe sleep apnea have a much higher mortality risk than people without sleep apnea, and this risk increases when sleep apnea is untreated.

WESTCHESTER, Ill. – Moderate to severe obstructive sleep apnea (OSA) is an independent risk factor for all-cause mortality, according to a study in the August 1 issue of the journal Sleep.

HOUSTON - New preclinical research shows that cannabinoid cell surface receptor CB1 plays a tumor-suppressing role in human colorectal cancer, scientists report in the Aug. 1 edition of the journal Cancer Research.

CB1 is well-established for relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. It now may serve as a new path for cancer prevention or treatment.

Alexandria, VA – A new invited article in the August 2008 edition of Otolaryngology – Head and Neck Surgery calls on the U.S. medical community to develop a national consensus on ethical guidelines for physicians who care for patients, victims, and casualties of disasters such as hurricanes, tornadoes, floods, or terrorist attacks.

PHILADELPHIA – Researchers in Germany have discovered that methadone, an agent used to break addiction to opioid drugs, has surprising killing power against leukemia cells, including treatment resistant forms of the cancer.

Their laboratory study, published in the August 1 issue of Cancer Research, a journal of the American Association for Cancer Research, suggests that methadone holds promise as a new therapy for leukemia, especially in patients whose cancer no longer responds to chemotherapy and radiation.

PHILADELPHIA – Based on a pilot study in children with sarcoma, researchers at the National Institutes of Health (NIH) believe that immunotherapy could prove beneficial in treating high-risk forms of this cancer.

Judged by the astonishing increase in journal papers written by scientists in China, there can be little doubt that China is finding its place as one of the world's scientific power houses. Michael Banks, Physics World's News Editor, quantifies this surge in scientific output from China and asks whether quality matches quantity in August's Physics World.