Body

MONTREAL, QC and DURHAM, N.C. - August 5, 2008 – Argos Therapeutics and Université de Montréal today announced the presentation of new information on Argos'process for developing dendritic cell-based immunotherapies for HIV. Results from the study demonstrate that loading monocyte-derived dendritic cells with combinations of HIV antigen RNA stimulates the expansion of HIV-specific T cells, which attack and kill HIV-infected cells.

To avoid producing vaccines that treat the wrong strains during flu season, the FDA should consider deferring some of its selections as well as other changes to the vaccine composition, according to a study by two decision analysts published in a journal of the Institute for Operations Research and the Management Sciences (INFORMS®).

"Repeated Commit-or-Defer Decisions with a Deadline: The Influenza Vaccine Composition" is by Laura J. Kornish of the University of Colorado and Ralph L. Keeney of Duke University. It appears in the current issue of Operations Research.

RIVERSIDE, Calif. – Cerambycid beetles, also known as long-horned beetles, can cause severe damage to standing trees, logs and lumber. How then might they be promptly detected and their numbers swiftly controlled?

Two entomologists have devised a solution based on how male and female cerambycid beetles communicate with, and attract, each other.

University of Minnesota researchers have answered a key question as to why antiretroviral therapy isn't effective in restoring immunity in HIV-infected patients.

Once a person is infected with the virus, fibrosis, or scarring, occurs in the lymph nodes – the home of T cells that fight infection. And once fibrosis occurs, T cells can't repopulate the lymph nodes when HIV therapy begins, said Timothy Schacker, M.D., professor of medicine and principal investigator on the study.

STANFORD, Calif. - A drug commonly used in the developing world to prevent transmission of HIV from mother to child persists in the breast milk and blood of the mothers, putting them and their babies at risk for developing drug-resistant strains of the virus, according to researchers at the Stanford University School of Medicine.

(Santa Barbara, Calif.) -- Researchers at UC Santa Barbara have recently reached what they are calling a milestone in experimental quantum mechanics.

In a paper published in the July 17 issue of the journal Nature, UCSB physicists Max Hofheinz, John Martinis, and Andrew Cleland documented how they used a superconducting electronic circuit known as a Josephson phase qubit, developed in Martinis's lab, to controllably pump microwave photons, one at a time, into a superconducting microwave resonator.

New insight into key players in iron metabolism has yielded a novel tool for distinguishing among root causes of iron overload or deficiency in humans, the researchers report in the August issue of Cell Metabolism, a publication of Cell Press. While the body needs iron to produce hemoglobin, a substance in red blood cells that enables them to carry oxygen, too much iron can build up and eventually damage organs.

SALT LAKE CITY – University of Utah School of Medicine researchers have developed a new tool that facilitates diagnosis of anemia related to chronic illness, as well as diseases of iron overload. The results of a study detailing the new tool are published in the August 2008 issue of the journal Cell Metabolism, a publication of Cell Press.

Richmond, Va. (Aug. 5, 2008) — Researchers at the Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have published findings that implicate a new chemoprevention gene therapy (CGT) for preventing and treating pancreatic cancer, one of the most lethal and treatment-resistant forms of cancer.

Planning and anticipating occur so frequently in our everyday lives that it is hard to imagine a time when we didn't have this capability. But just as many other capacities develop, so does this mental time traveling ability. Researchers have recently explored how children comprehend the future and ways that this understanding can be affected by, for example, their current physiological state.

COLUMBIA, Mo. – Recently, researchers at the Salk Institute for Biological Studies, a research organization focused on biology and its relation to health, published a study in the journal Cell on the results of a substance that increased exercise endurance without daily exertion when tested in mice. Media reports have described this substance as an "exercise pill," potentially eliminating the need for exercise.

(Boston) An international research team in Antarctica led by David Marchant, an associate professor of earth sciences at Boston University, has reported the discovery of exceptionally well-preserved freshwater fossils including mosses, microscopic one-celled algae, known as diatoms, small fresh water crustaceans, and insects that represent the last traces of tundra in the southernmost region of the continent before a dramatic and enduring cooling occurred some 14 million years ago.

FAIRFAX, Va.—Endovascular repair—fixing an injury in a blood vessel from inside that vessel—is a better option for individuals who receive highly lethal injuries from high-speed collisions or falls (together referred to as blunt trauma) and is shown to save more lives and nearly eliminate paraplegia (the loss of the ability to move and/or feel both legs), a complication of surgical repair for thoracic aortic aneurysms.

Researchers have developed a ground-breaking procedure that could avoid the need for transplant patients to spend the rest of their lives taking a cocktail of drugs to stop their system from rejecting their new organ, according to a series of papers in the August issue of Transplant International.

The team, led by Professor Fred Fandrich from the University of Schleswig-Holstein in Kiel, Germany, has developed a technique based on tailor-made regulatory cells.