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Most trauma professionals and members of the general public say they would prefer palliative care following a severe injury if physicians determined aggressive critical care would not save their lives, according to a report in the August issue of Archives of Surgery, one of the JAMA/Archives journals. However, trauma care professionals and other individuals differ in their opinions regarding patients' rights to demand care and the role of divine intervention in recovery from an injury.

Smoking appears to be associated with an increased rate of hemorrhage (bleeding) in patients who undergo uvulopalatopharyngoplasty (UPPP, a surgical procedure used to remove excess tissue from the throat) with tonsillectomy (a surgical procedure in which the tonsils are removed), but not in those who undergo tonsillectomy alone, according to a report in the August issue of Archives of Otolaryngology−Head & Neck Surgery, one of the JAMA/Archives journals.

Teens report that they would pay about $275 to have never had acne, and are willing to pay considerably more to be acne-free than to have 50 percent clearance of their acne or to have clear skin with acne scars, according to a report in the August issue of Archives of Dermatology, one of the JAMA/Archives journals.

Teenagers are notorious for having bad sleep habits. New research suggests that having trouble staying awake the next day might not be the only consequence they face. In the first study to look at the relationship between not getting enough sleep and blood pressure in healthy adolescents, researchers found that healthy teens (ages 13 to 16 years old) who slept less than 6.5 hours a night were 2.5 times more likely to have elevated blood pressure compared to those who slept longer.

If you knew what possessed the young Jim Sacchettini to become a biochemist, you might look upon the "bar scene" more approvingly. But that story's for later.

Instead, ponder what Sacchettini calls "the diseases of the poor" – infectious diseases that not long ago were considered wiped from the face of the Earth - tuberculosis and malaria, for instance.

Sacchettini saw these maladies firsthand in the Bronx. He had gone there in 1990 from St. Louis, Mo., after earning his doctorate at Washington University.

WASHINGTON, DC—Children's National Medical Center immunologist and blood and marrow transplant physician Naynesh Kamani, MD, will serve as the study co-chair for a new national clinical trial of unrelated donor marrow and umbilical cord blood transplants for severe

WINSTON-SALEM, N.C. – Ashok Hemal, M.D., a urologic surgeon from Wake Forest University Baptist Medical Center, and colleagues have reported success using robot-assisted laparoscopic surgery to repair abnormal openings between the bladder and vagina known as fistulas. Reporting on their experience with seven patients, Hemal and colleagues have the world's largest known success with the procedure.

Their report appears online in the Journal of Urology and will be included in a future print issue.

Researchers trying to determine whether nature or nurture determines an ant's status in the colony have found a surprising answer.

Both.

Nature (that is, the ant's genetic makeup) and nurture (what it eats, for example) play a role in determining the fate of the Florida harvester ant, Pogonomyrmex badius, a resilient creature found in many parts of the southeastern United States.

CINCINNATI—One in three U.S. public schools are in the "air pollution danger zone," according to new research from the University of Cincinnati (UC).

UC researchers have found that more than 30 percent of American public schools are within 400 meters, or a quarter mile, of major highways that consistently serve as main truck and traffic routes.

Research has shown that proximity to major highways—and thus environmental pollutants, such as aerosolizing diesel exhaust particles—can leave school-age children more susceptible to respiratory diseases later in life.

INDIANAPOLIS – Family members are often called upon to make medical choices for patients who are unable to do so themselves. Researchers led by Alexia Torke, M.D., of the Indiana University School of Medicine and the Regenstrief Institute, Inc., studied how physicians treating these patients interacted with surrogate decision-makers.

Mount Sinai researchers have developed a new gene silencing technology that could be used to target genes that can lead to the development of certain diseases. This technology could pave the way for preventing diseases where gene dysfunction plays a role. The groundbreaking research was led by Ming-Ming Zhou, Ph.D., Professor and Chairman of the Department of Structural and Chemical Biology at Mount Sinai School of Medicine. The findings, which will be published in the September issue of Nature Cell Biology, are available on the magazine's web site as of today.

PHILADELPHIA—Tetra-Amido Macrocyclic Ligands (TAMLs) are environmentally friendly catalysts with a host of applications for reducing and cleaning up pollutants, and a prime example of "green chemistry." Carnegie Mellon University's Terry Collins, the catalyst's inventor, believes that the small-molecule catalysts have the potential to be even more effective than previously proven. Collins will discuss how iron-TAMLs (Fe-TAMLs) work and areas for further research, citing evidence from mechanistic and kinetic studies of the catalyst on Monday, Aug.

RICHLAND, Wash. -- Bedsprings aren't often found in biology. Now, chemists have succeeded in making a layer of tiny protein coils attached to a surface, much like miniature bedsprings in a frame. This thin film made of stable and very pure helices can help researchers develop molecular electronics or solar cells, or to divine the biology of proteins.

COLUMBUS, Ohio – Seeking to improve on nature, scientists used a spice-based compound as a starting point and developed synthetic molecules that, in lab settings, are able to kill cancer cells and stop the cells from spreading.

The researchers are combining organic chemistry, computer-aided design and molecular biology techniques in developing and testing pharmaceutical compounds that can fight breast and prostate cancer cells. The synthetic molecules are derived from curcumin, a naturally occurring compound found in the spice turmeric.