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The treatment of pancreatic cancer remains a great challenge. The majority of patients with pancreatic cancer developed major depression. Antidepressant treatment has been accepted as one of the new strategies in cancer adjuvant therapy. However, systemic studies on the treatment of depression in patient with cancer have not been well documented.

The liver plays a pivotal role in fuel and energy metabolism. Many studies have shown that patients with liver cirrhosis have nutrient and energy metabolism imbalances, which lead to malnutrition and can seriously affect their prognosis. However, the characteristics of the fuel and energy metabolism in patients with chronic severe hepatitis are not clear.

Chicago, IL – Despite little publicity surrounding the ailment, seniors may be facing an emerging epidemic in the form of bisphosphonate osteonecrosis ("bone death"), a debilitating ailment of the jawbone that patients are predisposed to, through common treatments for the more well-known ailment osteoporosis. Experts in the field of otolaryngology and dentistry will discuss this emerging problem and its diagnosis and treatment at the 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in Chicago, IL.

Thirteen fluorescent labeled polymorphic microsatellite markers were analyzed in 83 cases of colorectal carcinoma and matched normal tissue DNA by polymerase chain reaction (PCR). PCR products were eletrophoresed on an ABI 377 DNA sequencer. Genescan 3.7 and Genotype 3.7 software were used for loss of heterozygosity (LOH) scanning and analysis. Compared with clinicopathological features, significant relationship was observed between LOH frequencies on D4S3018 locus.

Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed. Only two cases of a small cell neuroendocrine carcinoma associated with an adenoma have been described in a retrospective study. There has been no radiology report describing the imaging features of these coexisting tumors of the ampullary region.

HBV infection may lead to acute liver disease, chronic active hepatitis, liver cirrhosis, and hepatocellular carcinoma. Over 350 million people worldwide are estimated to be infected chronically by HBV and are therefore at risk of liver failure, cirrhosis, or hepatocellular carcinoma. The principal treatment for chronic hepatitis B (CHB) involves the use of interferon alpha (IFN-a) or nucleoside analogs. In vitro analysis of clinical HBV isolates is currently difficult for lacking of HBV cellular culture model

Chicago, IL – In the six decades since French and American surgeons implanted the first cochlear hearing devices, the procedure in children has become reliable, safe, and relatively free of severe complications, according to research presented during the 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in Chicago, IL.

It has long been known that environmental factors play a part in the development of rheumatoid arthritis; smoking and drinking alcohol, along with heredity, are particularly instrumental in increasing the risk of the disease. Scientists at Karolinska Institutet have now produced results that suggest that working environment factors can also increase the chances of developing rheumatoid arthritis.

Probiotic bacteria are widely used to relieve the symptoms of many disorders such as inflammatory bowel syndrome, diarrhea, and allergies. Probiotic mixtures have also been found to reduce the symptoms of diarrhea. In children a probiotic bacterium L. rhamnosus GG has been shown to prevent the onset of atopy and allergies. However, the mechanisms that cause these beneficial actions are yet to be characterized.

When meeting someone for the first time, the second question that is usually asked (following "what's your name?") is "where do you live?". Until recently, it was not apparent just how revealing that answer may be. Although behavioral research has suggested that people who are extremely outgoing have a tendency to relocate often, was unknown if specific areas attract particular personality types.

Modern cancer care is critically dependent on imaging technologies, which are used to detect early tumors and guide their therapy or surgery. Molecular imaging technologies provide information about the functional or metabolic characteristics of malignancies, tumor stage and therapeutical response, and tumor recurrence; whereas conventional imaging technologies predominantly assess the tumor's anatomical or morphologic features including its size, density, shape, etc.

UC and CD, the two major forms of IBD are chronic, idiopathic inflammatory conditions of the gut with a typically relapsing and remitting course. A prominent feature in mucosal biopsies from patients with active IBD is infiltration by neutrophil granulocytes. Moreover, the number of eosinophil granulocytes is also increased in IBD. Upon activation, neutrophils release Calprotectin and MPO, two major neutrophil proteins, while eosinophils release the protein, EPX.

PAEF is a rare but often life-threatening cause of massive gastrointestinal bleeding. PAEFs have a mortality rate of nearly 100% in the absence of surgical intervention, and in most case, the diagnosis is not established preoperatively. This report presents one such case wherein the cause of death was PAEF-induced massive gastrointestinal bleeding that occurred after discharge of the patient from the hospital. Few previous reports on PAEF provide both the clinical course, including gastrointestinal endoscopic findings, and detailed autopsy findings.

Chicago, IL – Efforts to fill in holes in data regarding the primary causes of tonsillectomy in adults have determined that chronic infection is the most common reason for the procedure, according to new research presented at the 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in Chicago, IL.

Researchers at the University of Bath and conservationists from the Great Bustard Group will be releasing 19 birds on Salisbury Plain on Thursday 25 September as part of an ongoing reintroduction project in the UK.