Body

Orlando, FL, October 6, 2008 – New research presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando emphasizes the importance of adequate bowel preparation prior to colonoscopy, and highlights the remarkable effectiveness of colonoscopy in detecting and removing pre-cancerous polyps, particularly tiny, flat, potentially pre-cancerous growths in the colon known as "sessile serrated adenomas."

Orlando, FL, Oct 6, 2008 – New research presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando found patients with inflammatory bowel disease or chronic liver disease were at increased risk of developing Vitamin D deficiencies. Two separate studies highlight the importance of regular Vitamin D checkups in the evaluation of patients with certain digestive diseases.

For IBD Patients, Vitamin D Deficiency Associated with Lower Quality of Life and Higher Disease Activity

Orlando, FL October 6, 2008 – While smoking poses a health threat to both men and women, women require less tobacco exposure than men to have a significant increased risk for colorectal cancer, according to new research presented at the 73rd Annual ACG Scientific Meeting in Orlando. In a separate analysis, researchers found smoking may increase the risk of pancreatic cancer precursor lesions, particularly in patients with a strong family history of the disease.

PHILADELPHIA – October 6, 2008 – Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced the results from a multidisciplinary analysis of in vitro and in vivo data of LIALDA® (mesalamine) versus Asacol® (mesalamine) that investigated factors including transit and disintegration of tablets along with tablet coating thickness that may affect a consistent release of 5-aminosalicylate acid (5-ASA) in both therapies. This analysis will be presented at The American College of Gastroenterology (ACG) meeting in Orlando.

ROCHESTER, Minn. -- With a long-held commitment to continuously improving the quality and safety of patient care, Mayo Clinic researchers are recommending a new technologically-advanced labeling system aimed at reducing specimen labeling errors in a high-volume gastrointestinal endoscopy center. That conclusion is based on the results of a study they are presenting at the 2008 American College of Gastroenterology (ACG) Annual Meeting.

ROCHESTER, Minn. -- A study led by Mayo Clinic has found that infliximab (Remicade®) administered alone (monotherapy) or in combination with azathioprine is a more effective treatment for patients with moderate to severe Crohn's disease than azathioprine alone. These findings were presented today at the 2008 American College of Gastroenterology (ACG) Annual Meeting.

Orlando, FL, Oct 6, 2008 – New research presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando found patients with inflammatory bowel disease or chronic liver disease were at increased risk of developing Vitamin D deficiencies. Two separate studies highlight the importance of regular Vitamin D checkups in the evaluation of patients with certain digestive diseases.

For IBD Patients, Vitamin D Deficiency Associated with Lower Quality of Life and Higher Disease Activity

Orlando, FL, October 6, 2008 – Two studies presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando highlight new technologies with the potential to improve the detection of colorectal polyps and flat lesions during colonoscopy. The American College of Gastroenterology endorses colonoscopy as the preferred strategy for colorectal cancer screening because of its remarkable sensitivity in detecting and removing polyps before they become cancerous.

Orlando, FL, October 6, 2008 – Endoscopic therapy is emerging as an alternative to surgery in patients with esophageal cancer given the low likelihood of spread to the lymph nodes. New research presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando evaluated the long-term efficacy of endoscopic mucosal resection, or EMR, in the treatment of patients with early stage esophageal cancer or Barrett's esophagus. Two separate studies suggest EMR is an effective treatment alternative to surgery and generally yields positive long-term results.

Orlando, FL, October 6, 2008 – Could there be a link between high levels of air pollution and the risk of appendicitis? New research presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando, suggests a novel connection.

"Adult onset appendicitis is a common condition whose cause is unclear and almost universally requires surgery," explained Dr. Gilaad G. Kaplan of the University of Calgary.

Orlando, FL, October 6, 2008 – A screening program for colon cancer in patients starting ten years prior to Medicare eligibility, at age 55 instead of Medicare's 65, would save at least two dollars for every dollar spent, according to a new study presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando.

Orlando, FL, October 6, 2008 – In a large U.S. population-based study presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology, metabolic syndrome patients had a 75 percent higher risk of colorectal cancer compared to those without metabolic syndrome.

Orlando, FL, October 6, 2008 – Several studies presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando highlight the safety and efficacy of probiotics in improving symptoms and normalizing bowel movement frequency in patients suffering from constipation or diarrhea related to Irritable Bowel Syndrome (IBS).

New Systematic Review of Probiotics in IBS

TEMPE, Ariz. – From majestic African elephants to tiny and often unappreciated rodents, mammals on Earth are in a state of crisis. One in four mammal species on Earth is being pushed to extinction, according to the Global Mammal Assessment, the most comprehensive assessment of the world's mammals.

Despite efforts to include more healthy choices at schools, standard offerings from vending machines – including fruit juices – are giving students more calories than they need.

Recent figures from the HEALTHY Study, a nationwide effort led by Temple University to curb obesity and type 2 diabetes in middle school students, found vending machines beverages had added sugars, high calorie 100 percent fruit juices, and snacks over 200 hundred calories.

The data will be presented at The Obesity Society's annual meeting in early October.