Body

NEW YORK (July 8, 2009) – A new finding reveals that African-American patients with breast, ovarian, and prostate cancer tend to die earlier than patients of other races with these cancers, even when they receive identical medical treatment and when socioeconomic factors are controlled for. The finding, an analysis of almost 20,000 patient records from 35 clinical trials, points to biological or genetic factors as the potential source of the survival gap.

Scientists are reporting for the first time that the use of weed killers in farmers' fields boosts the nutritional value of an important food a crop. Application of two common herbicides to several varieties of sweet corn significantly increased the amount of key nutrients termed carotenoids in the corn kernels, according to a study scheduled for publication in the July 22 issue of ACS' Journal of Agricultural and Food Chemistry, a bi-weekly publication.

The restoration of a 2,000-year-old bronze sculpture of the famed ancient Greek athlete Apoxyomenos may help modern scientists understand how to prevent metal corrosion, discover the safest ways to permanently store nuclear waste, and understand other perplexing problems. That's the conclusion of a new study on the so-called "biomineralization" of Apoxyomenos appearing in the current issue of ACS' Crystal Growth & Design, a bi-monthly journal. Best known as "The Scraper," the statue depicts an athlete scraping sweat and dust from his body with a small curved instrument.

Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR) a DNA test widely used in criminal investigations, disease diagnosis, biological research and other applications. The new method could lead to expanded use of PCR in medicine, the criminal justice system and elsewhere, the researchers say. Their study is scheduled for the July 15 issue of Analytical Chemistry, a semi-monthly journal.

CHAMPAIGN, Ill. — Bisphenol A, a chemical widely used in plastics and known to cause reproductive problems in the offspring of pregnant mice exposed to it, also has been found to retard the growth of follicles of adult mice and hinder their production of steroid hormones, researchers report.

Their study is the first to show that chronic exposure to low doses of BPA can impair the growth and function of adult reproductive cells. The researchers will describe their findings this month at the annual meeting of the Society for the Study of Reproduction.

(Boston) – Boston University School of Medicine researchers (BUSM) have observed in a study of pregnant women that consumption of at least seven servings per day of fruits and vegetables moderately reduced the risk of developing an upper respiratory tract infection (URTI). The BUSM study appears online in the journal Public Health Nutrition.

Iatrogenic perforation of cancer of the esophagus or the gastroesophageal (GE) junction is a severe complication. Its incidence has increased most likely because of more aggressive palliative endoscopic therapy and the current widespread use of endoscopic ultrasound (EUS) for accurate preoperative staging. Therapy, i.e. conservative versus surgical treatment remains controversial.

Bowel preparation has been reported inadequate in 10%-75% of colonoscopic examinations. None of the preparations reached all the requirements of safety, acceptance for patients with negligible discomfort, and rapid cleansing. Polyethyleneglycol is considered to be the gold standard for colonoscopic bowel preparation (Grade IA), and aqueous sodium phosphate was an alternative regimen to PEG solution (Grade IA). This consensus also stated that adjunctive therapy, such as bisacodyl, metoclopramide, and simethicone, was shown to improve the quality of bowel preparation.

Pluronic surfactants are synthetic copolymers based on ethylene oxide and propylene oxide. It has been reported that a nonionic L-81, effectively inhibits absorption of dietary lipids from the intestine and secretion of VLDL and LDL from the liver. Although L-81 is a potent anti-obesity drug, its potential in alleviating obesity-induced insulin resistance and type 2 diabetes has not been fully explored.

Nanyang Technological University (NTU)'s Associate Professor Zhong Guofu has made a significant contribution to the field of organic chemistry, in particular the study of using small organic molecules as catalysts, in the synthesis process called organocatalysis. Such synthesis process takes place for example, during the production of chiral drugs.

An independent external validation of QRISK® — a new score for predicting a person's risk of heart disease — has shown that it performs better than the existing test and should be recommended for use in the United Kingdom by the National Institute for Health and Clinical Excellence (NICE).

The University of Nottingham and leading healthcare systems supplier EMIS worked together, through the not-for-profit partnership QResearch, to develop the ground-breaking formula which has been strongly endorsed in new research published in the British Medical Journal.

BIRMINGHAM, Ala. – Researchers at the University of Alabama at Birmingham (UAB) have discovered a molecular coupling factor that helps bones grow and remodel themselves to stay strong, a finding that could lead to better bone-building therapies and new osteoporosis drugs, the researchers said

A Monash University study has proven a critical link between obesity and the onset of Type 2 diabetes, a discovery which could lead to the design of a drug to prevent the disease.

The findings were published today in respected journal Cell Metabolism.

The team, led by Associate Professor Matthew Watt, discovered that fat cells release a novel protein called PEDF (pigment epithelium-derived factor), which triggers a chain of events and interactions that lead to development of Type 2 diabetes.

A rapid rise in unemployment can be linked to an increase in suicides, homicides, and alcohol abuse, but job programs can successfully mitigate these rates, according to a new study reported in the "Lancet" medical journal.