Body

ATLANTA - A study of how HIV mutates in response to immune system pressure by Emory Vaccine Center researchers shows that the virus can take several escape routes, not one preferred route.

The results are online and scheduled for publication in the September issue of the journal Public Library of Science Pathogens.

(PHILADELPHIA) A person, usually a child, dies of rabies every 20 minutes. However, only one inoculation may be all it takes for rabies vaccination, according to new research published in the Journal of Infectious Diseases by researchers at the Jefferson Vaccine Center.

The age at which a person takes a first drink may influence genes linked to alcoholism, making the youngest drinkers the most susceptible to severe problems.

For immediate release: Sept. 18, 2009Nevada professor discovers new way to calculate body's "Maximum Weight Limit"RENO, Nev. – Most of us are familiar with the term, Body Mass Index, or BMI, as an index to determine healthy body weight. But, calculating BMI involves a complex formula: weight in pounds is multiplied by 703, and then divided by height in inches squared.

Physicians at The Mount Sinai Medical Center in New York became the first in the U.S. to ablate atrial fibrillation using a visually-guided laser balloon catheter. The procedure was performed September 15 by Vivek Y. Reddy, MD, Professor of Medicine and Director of the Cardiac Arrhythmia Service at Mount Sinai Heart, and his colleague, Srinivas R. Dukkipati, MD, Director of Mount Sinai's Experimental Electrophysiology Laboratory.

Bugs in boxes are helping University of California, Davis, researcher Alan Hastings improve scientific tools used to predict the spread of invasive plants and animals.

In today's edition of the journal Science, Hastings and a University of Colorado colleague report their latest findings from both a tightly controlled laboratory experiment and a mathematical model: When they released 600 identical beetles and let them spread at will through 30 identical landscapes over 13 generations, there was a surprising amount of difference in the outcome.

Marilyn Graham was 56 when she signed up for a grueling hour of cycling each morning for 12 weeks, occasionally decked out in a mask, a heart monitor and a bag of intravenous fluid and subjected to needle pricks to obtain blood samples.

"I was probably the biggest whiner of the group, complaining loudly about the seats and how my butt hurt," said Graham, who writes software for business units on the University of California, Berkeley campus. "It was really intense, and on some days my legs felt like wet noodles. On a cranky day I'd say, 'Let me off this stupid bike!'"

New Rochelle, NY, September 17, 2009—Risk factors for metabolic syndrome, such as obesity, high blood pressure, and elevated blood lipid levels, can increase a person's healthcare costs nearly 1.6-fold, or about $2,000 per year. For each additional risk factor those costs rise an average of 24%, according to an illuminating article in a recent issue of Metabolic Syndrome and Related Disorders, a peer-reviewed journal published by Mary Ann Liebert, Inc. The article is available free online at www.liebertpub.com/met

A team of researchers from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla have developed a safe strategy for reprogramming cells to a pluripotent state without use of viral vectors or genomic insertions. Their studies reveal that these induced pluripotent stem cells (iPSCs) are very similar to human embryonic stem cells, yet maintain a "transcriptional signature." In essence, these cells retain some memory of the donor cells they once were.

Many biopharmaceuticals comprise small proteins that are quickly eliminated from the body. Scientists at the Technische Universitaet Muenchen (TUM) combine such small proteins with a kind of molecular balloon that swells and thus prolongs the half-life of the proteins in the body. The TUM spin-off XL-Protein GmbH has now started to further develop this new technology with blockbuster potential.

Researchers at the Johns Hopkins School of Medicine have discovered how one antioxidant protein controls the activity of another protein, critical for the development of spinal cord neurons. The research, publishing this week in Cell, describes a never-before known mechanism of protein control.

Less than one third of healthcare workers have themselves vaccinated against classic influenza. This reluctance is astounding, firstly because vaccination against influenza viruses is considered safe and effective and secondly because it has been proved to prevent nosocomial transmission of disease to patients—provided at least 50% of employees have been vaccinated.

Korean computer scientists have developed a security policy specification for home networks that could make us more secure from cyber attack in our homes. They report details in the International Journal of Ad Hoc and Ubiquitous Computing.

University of Michigan (U-M) scientists have made an important step toward what could become the first vaccine in the U.S. to prevent urinary tract infections, if the robust immunity achieved in mice can be reproduced in humans. The findings are published September 18 in the open-access journal PLoS Pathogens.

As if a bad hangover wasn't enough of a deterrent, new research has shown how binge drinking weakens the body's ability to fight off infection for at least 24 hours afterwards. The study, published today in the open access journal BMC Immunology, focused on the effect of heavy drinking on toll-like receptor 4 (TLR4), a protein that has an important role in immune system activation.