Body

Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the National Cancer Institute.

Aspirin has been shown to prevent the recurrence of colorectal polyps, but it's not clear how it works. One hypothesis is that it may affect the levels of substances, such as C-reactive protein and others, that are markers of inflammation.

Individuals living in neighborhoods conducive to physical activity and providing access to healthy foods may have a lower risk of developing type 2 diabetes in a five-year period, according to a report in the October 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Higher concentration of urate (an antioxidant) in the blood and spinal fluid of patients with early Parkinson's disease is associated with slower rates of clinical decline, according to a report posted online today that will appear in the December print issue of Archives of Neurology, one of the JAMA/Archives journals.

As more extremely pre-term infants survive in Sweden, an increasing number of babies are experiencing vision problems caused by abnormalities involving the retina, according to a report in the October issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

A multi-national research team has discovered that two genetic factors converge to increase the risk of sudden cardiac death.

The investigators – from the United States, Italy and South Africa – report in the journal Circulation that variations in the gene NOS1AP increase the risk of cardiac symptoms and sudden death in patients who have an inherited cardiac disease called congenital long-QT syndrome.

New Orleans, LA – Dr. John England, Professor and Chairman of Neurology at LSU Health Sciences Center New Orleans, analyzed research findings and was responsible for the quality and accuracy of evidence analysis and the conclusions of the studies resulting in new guidelines for treating Lou Gehrig's disease, or amyotropic lateral sclerosis (ALS). The guidelines will be published in the October 13, 2009 issue of Neurology, the journal of the American Academy of Neurology.

Women who developed new-onset breast tenderness after starting estrogen plus progestin hormone replacement therapy were at significantly higher risk for developing breast cancer than women on the combination therapy who didn't experience such tenderness, according to a new UCLA study.

Parkinson disease progresses more slowly in patients who have higher levels of urate, a chemical that at very high level is associated with gout, scientists have found. While it's unknown whether the high levels actually somehow protect patients or simply serve as a marker of protection, the finding supports the idea that patients and doctors may one day be able to better predict the course of the illness.

STANFORD, Calif. — A Stanford University School of Medicine researcher has pinpointed the mechanism by which a gene associated with both autism and schizophrenia influences behavior in mice. And just recently, he received a $1.65 million government grant to expand his efforts to include many more such genes.

In new papers appearing this month in Science and the Proceedings of the National Academy of Sciences, University of Illinois biochemistry professor Raven H. Huang and his colleagues describe the first RNA repair system to be discovered in bacteria. This is only the second RNA repair system discovered to date (with two proteins from T4 phage, a virus that attacks bacteria, as the first).

Smithsonian researchers working in Colombia's Cerrejón coal mine have unearthed the first megafossil evidence of a neotropical rainforest. Titanoboa, the world's biggest snake, lived in this forest 58 million years ago at temperatures 3-5 C warmer than in rainforests today, indicating that rainforests flourished during warm periods.

Socially learned behavior and belief are much better candidates than genetics to explain the self-sacrificing behavior we see among strangers in societies, from soldiers to blood donors to those who contribute to food banks. This is the conclusion of a study by Adrian V. Bell and colleagues from the University of California Davis in the Oct. 12 edition of Proceedings of the National Academy of Sciences.

St. Louis, Oct. 9, 2009 — A new mouse model of amyotrophic lateral sclerosis (ALS) closely resembles humans with the paralyzing disorder, researchers at Washington University School of Medicine in St. Louis report.

Like humans with ALS, the new genetically engineered mouse develops progressive paralysis; loses muscle mass and specific types of motor neurons, which are nerve cells that control muscles; and dies of the disorder, which is currently fatal in humans.

The 40,000 or so spiders that have been described are generally known as strict predators, trapping their prey in elaborate webs or hunting them down directly. But researchers have found one notable exception to this rule: The neotropical jumping spider known as Bagheera kiplingi represents the first instance known to science of a spider that dines primarily on vegetarian fare, according to a report published online on October 12th in Current Biology, a Cell Press publication.

There are approximately 40,000 species of spiders in the world, all of which have been thought to be strict predators that feed on insects or other animals. Now, scientists have found that a small Central American jumping spider has a uniquely different diet: the species Bagheera kiplingi feeds predominantly on plant food.