Researchers at the University of Maryland School of Medicine Center for Vaccine Development (CVD) have charted the extreme genetic differences that occur over time in the most dangerous malaria parasite in the world. While there is no approved vaccine for malaria, various experimental vaccines are in development. The CVD study suggests that developing a broadly protective vaccine for malaria may be challenging because the parasite's genetic makeup is so variable, constantly changing.
Body
University of California, Davis, researchers studying the 2009 H1N1 influenza virus, formerly referred to as "swine flu," have identified a group of immunologically important sites on the virus that are also present in seasonal flu viruses that have been circulating for years. These molecular sites appear to result in some level of immunity to the new virus in people who were exposed to the earlier influenza viruses.
LA JOLLA, CA—Although the human genome sequence faithfully lists (almost) every single DNA base of the roughly 3 billion bases that make up a human genome, it doesn't tell biologists much about how its function is regulated. Now, researchers at the Salk Institute provide the first detailed map of the human epigenome, the layer of genetic control beyond the regulation inherent in the sequence of the genes themselves.
While gripping, lifting or manipulating an object such as drinking from a cup or placing a book on a shelf is usually easy for most, it can be challenging for those with neurological diseases such as multiple sclerosis or Parkinson's, or for people who had a stroke. For them, the tight gripping can cause fatigue, making everyday tasks difficult.
After 15 years of research in the waters of the South Atlantic and Indian Oceans, scientists from the Wildlife Conservation Society, the American Museum of Natural History, and an international coalition of organizations have unveiled the largest genetic study of humpback whale populations ever conducted in the Southern Hemisphere.
ROCHESTER, Minn. -- Mayo Clinic surgical researchers are reporting a 93 percent success rate in recent animal tests of endoscopic repair of perforated ulcers. The goal is to advance the use of an endoscope -- which allows access to organs through natural openings, such as the mouth -- for a less invasive alternative to laparoscopic techniques (surgery performed through a small incision) or conventional surgery. They will present their findings from recent animal studies today at the American College of Surgeons 95th Clinical Congress in Chicago.
Researchers have established the conditions that foster formation of potentially dangerous levels of a toxic substance in the high-fructose corn syrup (HFCS) often fed to honey bees. Their study, which appears in ACS' bi-weekly Journal of Agricultural and Food Chemistry, could also help keep the substance out of soft drinks and dozens of other human foods that contain HFCS. The substance, hydroxymethylfurfural (HMF), forms mainly from heating fructose.
The "vegetable lamb" plant — once believed to bear fruit that ripened into a living baby sheep — produces substances that show promise in laboratory experiments as new treatments for osteoporosis, the bone-thinning disease. That's the conclusion of a new study in ACS' monthly Journal of Natural Products.
WINSTON-SALEM, N.C. – A newer, less expensive drug used to suppress the immune system and prevent organ rejection in kidney and pancreas transplant patients works just as well as its much more expensive counterpart, according to a new study by researchers at Wake Forest University Baptist Medical Center.
Such discoveries are vital in an era of skyrocketing health care costs and debate over health reform, said lead investigator Alan C. Farney, M.D., Ph.D., an associate professor of surgery in the Department of General Surgery, Transplantation Services.
Small classes in early grades improve test scores in later grades for students of all achievement levels, but low achievers get an extra boost. That's the finding of a study on the long-term effects of class size in the November issue of the American Journal of Education.
ANN ARBOR, Mich. — University of Michigan researchers have found that patients with severe cases of the H1N1 virus are at risk for developing severe complications, including pulmonary emboli, according to a study published today in the American Journal of Roentgenology.
A pulmonary embolism occurs when one or more arteries in the lungs become blocked. The condition can be life-threatening. However, if treated aggressively, blood thinners can reduce the risk of death.
Contestants on TV shows like Top Chef and Hell's Kitchen know that their meat-cutting skills will be scrutinized by a panel of unforgiving judges. Now, new archaeological evidence is getting the same scrutiny by scientists at Tel Aviv University and the University of Arizona.
Their research is providing new clues about how, where and when our communal habits of butchering meat developed, and they're changing the way anthropologists, zoologists and archaeologists think about our evolutionary development, economics and social behaviors through the millennia.
Bosses who are in over their heads are more likely to bully subordinates. That's because feelings of inadequacy trigger them to lash out at those around them, according to new research from the University of California, Berkeley, and the University of Southern California.
Laughter is an emotional expression that is innate in human beings. This means laughing at others is also believed to be a universal phenomenon. However, the fear of being laughed at causes some people enormous problems in their social lives. This is known as gelotophobia, a disorder that affects people in all cultures alike.
AUSTIN, Texas – A team of scientists, led by a biomedical engineer at The University of Texas at Austin, have demonstrated – for the first time – that mathematical models created from data obtained by DNA microarrays, can be used to correctly predict previously unknown cellular mechanisms. This brings biologists a step closer to one day being able to understand and control the inner workings of the cell as readily as NASA engineers plot the trajectories of spacecraft today.