Body

CHAMPAIGN, Ill. — A global collaborative has produced a first draft of the genome of a domesticated pig, an achievement that will lead to insights in agriculture, medicine, conservation and evolution.

A red-haired Duroc pig from a farm at the University of Illinois will now be among the growing list of domesticated animals that have had their genomes sequenced. Researchers will announce the achievement Monday (Nov. 2) at a meeting at the Wellcome Trust Sanger Institute in Hinxton, England.

Researchers from the University of Copenhagen and the Technical University of Denmark along with other collaborators in Denmark and the US found that the bacterium Pseudomonas aeruginosa can 'switch on' production of molecules that kill white blood cells – preventing the bacteria being eliminated by the body's immune system.

DURHAM, N.C. -- Going smaller could bring better results, especially when it comes to cancer-fighting drugs.

Duke University bioengineers have developed a simple and inexpensive method for loading cancer drug payloads into nano-scale delivery vehicles and demonstrated in animal models that this new nanoformulation can eliminate tumors after a single treatment. After delivering the drug to the tumor, the delivery vehicle breaks down into harmless byproducts, markedly decreasing the toxicity for the recipient.

A study featured in the November issue of the Journal of Thoracic Oncology confirms the success of a simple questionnaire designed to identify patients at high risk of lung cancer. Initiated in 2001, the current study confirmed 18 cases of cancer of the original 430 patients who qualified as high risk after completing a five-minute questionnaire.

Improving survival among dialysis patients may increase treatment costs significantly, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. The authors created models of a 100 patient dialysis treatment center and a program with 7,500 hemodialysis patients (the approximate number of such patients in the Province of Ontario, Canada). Improving patient survival increased costs in the 100 patient model by $5 million over 10 years, and in the 7,500 patient model by $400 million over 10 years.

Individuals who consume a diet high in sodium or artificially sweetened drinks are more likely to experience a decline in kidney function, according to two papers being presented at the American Society of Nephrology's annual meeting in San Diego, California.

Julie Lin MD, MPH, FASN and Gary Curhan, MD, ScD, FASN of Brigham and Women's Hospital studied more than 3,000 women participating in the Nurses' Health Study to identify the impact of sodium and sweetened drinks on kidney function.

Charcoal may provide a new approach to managing the high rate of heart disease in patients with advanced kidney disease, according to preliminary research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

Switching to a newer type of immunosuppressant drug may reduce the high rate of skin cancer after kidney transplantation, according to research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

Individuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. The findings indicate that having lupus should not keep individuals from seeking a kidney transplant if they need one.

A research team at Vanderbilt University has developed an innovative optical system to simultaneously image electrical activity and metabolic properties in the same region of a heart, to study the complex mechanisms that lead to sudden cardiac arrest.

(WASHINGTON - October 30, 2009) – Targeted immunotherapy has been an attractive new therapeutic area for a number of cancers because it has the potential to destroy tumor cells without damaging surrounding normal tissue. New study results demonstrate high success rates using specialized white blood cells to prevent or treat lymphoma associated with the Epstein-Barr virus (EBV-lymphoma) in patients who have received a hematopoietic stem cell transplant (HSCT).

Thousands of men are afflicted with an embarrassing and painful condition that triggers spontaneous, long-lasting erections. There are limited treatment options, but a solution could be on the way thanks to new research at The University of Texas Health Science Center at Houston.

Paleontologists from the University of California, Berkeley, and the Museum of the Rockies have wiped out two species of dome-headed dinosaur, one of them named three years ago – with great fanfare – after Hogwarts, the school attended by Harry Potter.

With the rapidly increasing problem of cardiovascular (CVD) disease in Asia Pacific (AP), there is an urgency to raise awareness of risk factors. The European Society of Cardiology (ESC) is addressing the need to develop and adopt an integrated approach to CVD management, through important events organised in the region.