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In PLoS Medicine this week a study conducted in a multi-country HIV treatment program in sub-Saharan Africa has found that pregnancy rates increase in HIV-infected women after they start antiretroviral therapy (ART).

The recent trend towards earlier UK springs and summers has been accelerating, according to a study published today (9 February 2010) in the scientific journal Global Change Biology.

The collaborative study, involving scientists from 12 UK research institutions, universities and conservation organisations, is the most comprehensive and rigorous assessment so far of long-term changes in the seasonal timing (phenology) of biological events across marine, freshwater and terrestrial environments in the UK.

The first head-to-head comparison of therapeutic monoclonal antibodies produced from plants versus the same antibodies produced from mammalian cells has shown that plant-produced antibodies can fight infection equally well.

Scientists from Washington University School of Medicine in St. Louis and Arizona State University conducted the comparison as a test of the potential for treating disease in developing nations with the significantly less expensive plant-based production technique.

Fewer than half of individuals who have "non-specific" chest pain (not explained by a well-known condition) experience relief from symptoms following standard medical care, according to a report in the February 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. In addition, one-tenth of those with persistent chest pain undergo potentially unnecessary diagnostic testing.

Australian general practitioners often treat patients with low back pain in a manner that does not appear to match the care endorsed by international clinical guidelines, according to a report in the February 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Fewer prostate cancers were detected by prostate-specific antigen (PSA) screening in the U.S. than in a European randomized trial because of lower screening sensitivity, according to a new brief communication published online February 8 in the Journal of the National Cancer Institute.

Glaucoma patients who take medication for the condition appear to have a reduced likelihood of death, according to a report in the February issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

Swelling commonly occurs in the corneas of mountain climbers, but does not appear to affect vision at altitudes of up to 6,300 meters (about 20,670 feet), according to a report in the February issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

PROVIDENCE, R.I. [Brown University] — Around 30 to 40 million years ago, grasses on Earth underwent an epic evolutionary upheaval. An assemblage capitalized on falling levels of atmospheric carbon dioxide by engineering an internal mechanism to concentrate the dwindling CO2 supply that, like a fuel-injection system in a car, could more efficiently convert sunlight and nutrients into energy.

Nicotine in third-hand smoke, the residue from tobacco smoke that clings to virtually all surfaces long after a cigarette has been extinguished, reacts with the common indoor air pollutant nitrous acid to produce dangerous carcinogens. This new potential health hazard was revealed in a multi-institutional study led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab).

Poor or declining handgrip strength in the oldest old is associated with poor survival and may be used as a tool to assess mortality, found an article in CMAJ (Canadian Medical Association Journal).

The fastest growing segment of the elderly population is the group older than 85 years, classified as the oldest old.

(SACRAMENTO, Calif.) — Advanced maternal age is linked to a significantly elevated risk of having a child with autism, regardless of the father's age, according to an exhaustive study of all births in California during the 1990s by UC Davis Health System researchers. Advanced paternal age is associated with elevated autism risk only when the father is older and the mother is under 30, the study found.

Deafness is the most common disorder of the senses. Tragically, it commonly strikes in early childhood, severely damaging an affected child's ability to learn speech and language. In many cases, children gradually lose their hearing to become profoundly deaf over a long period of months to years, but scientists know very little about how this progressive loss happens, making prospects for prevention and cure very slim.

Endometrial cancer is the most common cancer of the female reproductive tract, representing 6% of all cancers. There is currently no screening method or biomarker to indicate early presence of disease. "It is a very common malignancy that affects women of all ages" comments paper author Dr. Diego Castrillon. The cancer forms from the cells that grow along the inner lining of the uterus, which is called the endometrium, and usually it is diagnosed following patient reports of abnormal bleeding.

Rugged, hilly landscapes with a range of different habitat types can help maintain more stable butterfly populations and thus aid their conservation, according to new findings published today (8 February 2010) in the journal Ecology Letters.

The research, carried out by scientists from the Centre for Ecology & Hydrology, Butterfly Conservation and the University of York, has implications for how we might design landscapes better to help conserve species.