Body

Repairing birth defects in the womb. Inserting a tiny laser into the mother's uterus to seal off an abnormal blood flow and save fetal twins. Advancing the science that may allow doctors to deliver cells or DNA to treat sickle cell anemia and other genetic diseases before birth.

An increased dosage of Tamiflu (oseltamivir) for patients with critical illness is unlikely to be required in the treatment of pandemic (H1N1) influenza, contrary to current international guidelines, found a new study http://www.cmaj.ca/cgi/doi/10.1503/cmaj.092127 in CMAJ (Canadian Medical Association Journal) www.cmaj.ca.

Montreal, February 16, 2010 – Scientists battling malaria have earned a major victory. According to a Nature Genetics study, an international group of researchers has used genomics to decode the blueprint of Plasmodium falciparum – a strain of malaria most resistant to drugs that causes the most deaths around the world. The discovery may lead to advanced pharmaceuticals to fight the disease and prevent drug resistance among the 250 million people infected by malaria each year.

BLOOMINGTON, Ind. -- For winter sports athletes, including Olympians competing in Vancouver this week, the altitude of the sports venue can have a significant impact on performance, requiring athletes in skill sports, such as figure skating, ski jumping and snowboarding, to retool highly technical moves to accommodate more or less air resistance.

The putative skull of Saint Bridget (Birgitta) of Sweden that has been kept in a shrine in Vadstena Abbey is probably not authentic. A new study conducted at Uppsala University reveals that the two skulls, believed to be from Saint Bridget and her daughter Catherine (Katarina), is not from maternally related individuals. Furthermore, dating show that the skulls are not from the time period when Bridget and Catherine lived. The findings are published in the journal PLoS ONE.

Spanish researchers have developed a new mathematical model that permits to predict sport injuries from a series of equations. Their work has proved that sport injuries that affect the lower limbs in high-impact sport, such as football, athletics or basketball, can be predicted through the use of equations of logistic regression.

BLOOMINGTON, Ind. -- For winter sports athletes, including Olympians competing in Vancouver this week, the altitude of the sports venue can have a significant impact on performance, requiring athletes in skill sports, such as figure skating, ski jumping and snowboarding, to retool highly technical moves to accommodate more or less air resistance.

BIRMINGHAM, Ala. – New research from the University of Alabama at Birmingham (UAB) suggests that the ability of right side of the heart to pump blood may be an indication of the risk of death to heart-failure patients whose condition is caused by low function by the left side of their heart.

The ability of the two chambers of the heart, the left and right ventricles, to pump blood is described as ejection fraction. Healthy individuals typically have ejection fractions between 50 and 65 percent in both chambers.

LOS ANGELES - Since the dawn of the biological sciences, mankind has struggled to comprehend the relationships among the major groups of "jointed-legged" animals — the arthropods. Now, a team of researchers, including Dr. Joel Martin and Dr. Regina Wetzer from the Natural History Museum of Los Angeles County (NHM), has finished a completely new analysis of the evolutionary relationships among the arthropods, answering many questions that defied previous attempts to unravel how these creatures were connected. Their study is scheduled for publication in the journal Nature on Feb.

WEST LAFAYETTE, Ind. - Inserting a human protein important in cancer development was able to revive dying plants, showing an evolutionary link between plants and humans and possibly making it easier to study the protein's function in cancer development, a Purdue University study has shown.

The aminopeptidase M1 protein, or APM1, is critical for root development in plants. Arabidopsis plants lacking the protein will die, but can be rescued if the protein is restored.

Washington, DC – Combining tamoxifen, the world's most prescribed breast cancer agent, with a compound found in the flowering plant feverfew may prevent initial or future resistance to the drug, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

The finding, reported online in FASEB Feb. 12, provides new insight into the biological roots of that resistance, and also tests a novel way to get around it.

By unraveling the mysteries that exist within the molecular composition of mosquitoes, a team of Kansas State University researchers is trying to discover how the insects survive a parasite that causes malaria in humans.

A University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer.

Professor John Hopper of the University's School of Population Health says women vary greatly in their underlying risk of breast cancer. "These findings provide an insight into possible new pathways into the development of breast cancer."

A team of Catalan researchers has studied the changes in the make-up of animal populations following forest fires, and have concluded that malacological fauna are a good indicator of forest recovery. The conclusions of this study will help to ensure that post-fire forestry operations that do not harm these species of molluscs, which are sensitive to microclimatic conditions of the soil and vegetation structure.

How safe is circumcision? A systematic review, published in the open access journal BMC Urology has found that neonatal and infant circumcision by trained staff rarely results in problems. Risks can be higher among older boys, especially when undertaken by untrained providers with inappropriate equipment.