SALT LAKE CITY, March 1, 2010 – Like silkworm moths, butterflies and spiders, caddisfly larvae spin silk, but they do so underwater instead on dry land. Now, University of Utah researchers have discovered why the fly's silk is sticky when wet and how that may make it valuable as an adhesive tape during surgery.
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LA JOLLA, CA—The first order of business for any fledgling plant embryo is to determine which end grows the shoot and which end puts down roots. Now, researchers at the Salk Institute expose the turf wars between two groups of antagonistic genetic master switches that set up a plant's polar axis with a root on one end and a shoot on the other.
CHAMPAIGN, Ill. — A new technique to study protein dynamics in living cells has been created by a team of University of Illinois scientists, and evidence yielded from the new method indicates that an in vivo environment strongly modulates a protein's stability and folding rate, according to research accepted for publication in the journal Nature Methods and posted on the journal's Web site Feb. 28.
New research has identified four aspects of immune system disturbance which lead to the development of coeliac disease. Nearly 40 different inherited risk factors which predispose to the disease have now been identified. These latest findings could speed the way towards improved diagnostics and treatments for the autoimmune complaint that affects 1 in 100 of the population, and lead to insights into related conditions such as type 1 diabetes.
Digger wasps of the genus Philanthus, so-called beewolves, house beneficial bacteria on their cocoons that guarantee protection against harmful microorganisms. Scientists of the Max Planck Institute for Chemical Ecology in Jena teamed up with researchers at the University of Regensburg and the Jena Leibniz Institute for Natural Product Research – Hans-Knoell-Institute - and discovered that bacteria of the genus Streptomyces produce a cocktail of nine different antibiotics and thereby fend off invading pathogens.
COLUMBUS, Ohio – Reversing a protein deficiency through gene therapy can correct motor function, restore nerve signals and improve survival in mice that serve as a model for the lethal childhood disorder spinal muscular atrophy, new research shows.
DURHAM, NC — A novel technology for delivering nicotine to the lungs may soon give smokers a new way to kick the habit.
When compared to the nicotine vapor delivery system used in the Nicotrol/Nicorette inhaler, the new technology proved more effective at delivering nicotine to the blood stream. As a result, it provides immediate relief of withdrawal symptoms, according to Duke University Medical Center researchers. Users also reported the new nicotine delivery method was more tolerable than the current inhaler because it caused less throat irritation.
Metastases that were 2 millimeters or less in diameter ("micrometastases") in axillary lymph nodes detected on examination of a single section of the lymph nodes were associated with poorer disease-free and overall survival in breast cancer patients, according to a new study published online February 26 in the Journal of the National Cancer Institute.
SCOTTSDALE, Ariz. — Feb. 26, 2010 — Cancer researchers have high hopes for a new therapy for patients with certain types of lymphoma and leukemia.
PCI-32765 is a new drug being assessed in a Phase I clinical trial at the Virginia G. Piper Cancer Center in collaboration with the Clinical Division of the Translational Genomics Research Institute (TGen).
PHILADELPHIA - Researchers have found that one particularly aggressive type of blood cancer, mixed lineage leukemia (MLL), has an unusual way to keep the molecular motors running. The cancer cells rely on the normal version of an associated protein to stay alive.
MLL happens when a piece of chromosome 11 breaks off at the normal MLL-associated gene. The broken gene attaches itself to another chromosome, resulting in a fusion protein that eventually causes uncontrolled growth of blood cells.
The flowering plant - purple loosestrife - has been heading north since it was first introduced from Europe to the eastern seaboard 150 years ago. This exotic invader chokes out native species and has dramatically altered wetland habitats in North America. But it turns out it may have a vulnerability after all: the northern climate. Canadian scientists have found that adapting to the Great White North carries a severe reproductive penalty that may limit its spread.
The increasing prevalence of type 2 diabetes places a huge burden on its victims and poses a tremendous challenge to healthcare systems. Half of all heart attacks and stroke cases, but also many other deleterious conditions, can be ascribed to the effects of this metabolic syndrome. In Germany alone, some seven million people currently suffer from the disease, and the number of cases worldwide is projected to reach 370 million by the year 2030.
EAST LANSING, Mich. — A team of Michigan State University scientists ¬– using a new cooling method they created – have uncovered the inner workings of a key iron-containing enzyme, a discovery that could help researchers develop new medicines or understand how enzymes repair DNA.
Taurine/alpha-ketoglutarate dioxygenase, known as TauD, is a bacterial enzyme that is important in metabolism. Enzymes in this family repair DNA, sense oxygen and help produce antibiotics.
BIRMINGHAM, Ala. – Women given the human immunodeficiency virus (HIV) prevention drug nevirapine to protect their fetus should not use an HIV-drug regimen that contains nevirapine for at least one year after childbirth, say researchers at the University of Alabama at Birmingham (UAB).
SAN ANTONIO — A large nationwide study that includes neurologists from Mayo Clinic has found that blacks are substantially less likely than whites to know that they have atrial fibrillation or to use warfarin, the most common treatment for the condition. Atrial fibrillation, an abnormal heart rhythm, significantly increases risk of stroke. Warfarin is known to reduce that risk.