Body

Research carried out by a group of archaeologists from the Centre for Prehistoric Archaeological Heritage Studies of the Universitat Autònoma de Barcelona (CEPAP_UAB) at the Cova Gran site (Lleida) has contributed to stirring up scientific debate about the appearance of the first "modern" human beings on the Iberian Peninsula and their possible bearing on the extinction of the Neanderthals.

Each cusp of our teeth is regulated by genes which carefully control the development. A similar genetic puzzle also regulates the differentiation of our other organs and of all living organisms. A team of researchers at the Institute of Biotechnology of the University of Helsinki has developed a computer model reproducing population-level variation in complex structures like teeth and organs. The research takes a step towards the growing of correctly shaped teeth and other organs. The results were published last week in Nature, the esteemed science journal.

ATLANTA — A novel report explores the possible relationship between fluctuations in the stock market and the incidence of local heart attacks. The results were presented at the annual scientific meeting of the American College of Cardiology by a team of researchers from Duke University Medical Center.

TAMPA, Fla. (March 15, 2010)—Patient selection is key for vertebroplasty—a minimally invasive treatment performed by interventional radiologists in individuals with painful osteoporotic vertebral compression fractures that fail to respond to conventional medical therapy—to be effective and successful, according to a study of more than 1,500 persons who were followed over seven years.

TAMPA, Fla. (March 15, 2010)—Treating non-osteoporotic compression fractures in patients with multiple myeloma, a blood cancer, shows that the use of vertebroplasty—a minimally invasive treatment performed by interventional radiologists using imaging guidance that stabilizes collapsed vertebrae with the injection of medical-grade bone cement into the spine—results in a reduction of pain, medication usage and disability, according to researchers in the largest study of its kind at the Society of Interventional Radiology's 35th Annual Scientific Meeting in Tampa, Fla.

Researchers in Ireland have gained new understanding of the role played by the cilial protein Arl13b in Joubert syndrome (JS), a rare disorder characterized by developmental delay, mental retardation, and low muscle tone, among other symptoms. The findings will be published online March 15 in the Journal of Cell Biology (www.jcb.org).

Researchers in Germany show that a classical biological oscillator, the glycolytic oscillator, may increase damage to the heart during acute loss of oxygen (anoxia), and as may occur during ischemia. The study appears online March 15 in the Journal of General Physiology (www.jgp.org).

A new study from the Swedish medical university Karolinska Institutet shows that the blood vessels and muscles of the heart can regulate the uptake of fatty acids that we ingest through meat, milk products and other food. The researchers behind the study have also identified the way in which regulation is governed by the muscles themselves. The results, which are published in the scientific journal Nature, open the way for new forms of treatment for pathological fat accumulation in the muscles which, in turn, increases the risk of type II (adult) diabetes and cardiovascular disease.

ANN ARBOR, Mich. – A potent new inhibitor of HIV, derived from bananas, may open the door to new treatments to prevent sexual transmission of HIV, according to a University of Michigan Medical School study published this week.

Scientists have an emerging interest in lectins, naturally occurring chemicals in plants, because of their ability to halt the chain of reaction that leads to a variety of infections.

Boston, Mass. -- A large study from Children's Hospital Boston and the Boston-based Autism Consortium finds that a genetic test that samples the entire genome, known as chromosomal microarray analysis, has about three times the detection rate for genetic changes related to autism spectrum disorders (ASDs) than standard tests. Publishing in the April issue of Pediatrics (and online March 15), the authors urge that CMA become part of the first-line genetic work-up for ASDs.

Boston – March 15, 2010 – The Autism Consortium, an innovative research, clinical and family collaboration dedicated to catalyzing research and enhancing clinical care for families with autism spectrum disorders (ASDs), announced today that the results of its comparison study of genetic testing methods for autism spectrum disorders is available from the journal Pediatrics through early online release in their eFirst pages today and will appear in the journal's April issue.

WINSTON-SALEM, N.C. – Vitamin D is quickly becoming the "go-to" remedy for treating a wide range of illnesses, from osteoporosis to atherosclerosis. However, new evidence from a Wake Forest University School of Medicine study suggests that supplementing vitamin D in those with low levels may have different effects based on patient race and, in black individuals, the supplement could actually do harm.

CAMBRIDGE, Mass. -- Spiders and silkworms are masters of materials science, but scientists are finally catching up. Silks are among the toughest materials known, stronger and less brittle, pound for pound, than steel. Now scientists at MIT have unraveled some of their deepest secrets in research that could lead the way to the creation of synthetic materials that duplicate, or even exceed, the extraordinary properties of natural silk.

Codeine is by far the most widely used opiate in the world and one of the most commonly used painkillers. Codeine can be extracted directly from the plant, most codeine is synthesized from the much more abundant morphine found in opium poppy. Codeine is converted by an enzyme in the liver to morphine, which is the active analgesic and a naturally occurring compound in humans. Canadians spend more than $100 million every year on codeine-containing pharmaceutical products and are among the world's top consumers of the drug per capita.

UC Irvine researchers have played a leading role in the genome sequencing of Hydra, a freshwater polyp that has been a staple of biological research for 300 years.

In the March 14 online version of Nature, UCI biologists Robert Steele and Hans Bode, along with nine other UCI scientists and an international team of researchers, describe the genome sequence of an organism that continues to advance research on regeneration, stem cells and patterning.