As a result of the rarity of Wilson disease (WD) and the fact that liver biopsy is not performed routinely during follow-up, unless clinically indicated, the progression and timing of the liver pathology and its correlation with different anti-copper treatments or aminotransferase levels are poorly characterized. Previous studies have demonstrated the possibility of improvement of steatosis and inflammation grade, and of fibrosis stage during long-term follow-up.
Body
Biomolecules are medicine's jacks-of-all-trades: They are suitable for the diagnosis and treatment of cancer diseases; they are used in the treatment of multiple sclerosis and asthma; they help stimulate the build-up of the body's own immune defenses with flu and polio inoculations. In the laboratories of the pharmaceutical industry, new biomolecules are constantly being engineered: Specific antibodies, customized proteins and nucleic acids – the core components of genetic material - are considered promising candidates for therapeutic approaches.
It seems an infarction, but it's not. It's called Tako-Tsubo syndrome, or stress-induced cardiomyopathy, and it's a rare disease which at first used to be confused with the far more common (and dangerous) cardiac infarction. Patients arrive to the emergency room with the characteristic heart attack symptoms: acute pain in the chest, an electrocardiogram with the typical changes and the release of those enzymes associated with the usual heart disease.
Obstructive sleep apnea is associated with an increased risk of stroke in middle-aged and older adults, especially men, according to new results from a landmark study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Overall, sleep apnea more than doubles the risk of stroke in men. Obstructive sleep apnea is a common disorder in which the upper airway is intermittently narrowed or blocked, disrupting sleep and breathing during sleep.
A University of British Columbia doctoral candidate has discovered a previously unknown mechanism for silencing retroviruses, segments of genetic material that can lead to fatal mutations in a cell's DNA.
The findings, published today in the journal Nature, could lead to new cancer treatments that kill only tumour cells and leave healthy surrounding tissue unharmed.
A nutritional supplement could stimulate the production of stem cells integral for repairing the body. Research published in BioMed Central's open access Journal of Translational Medicine suggests that a commercially-available supplement can increase the blood circulation of hematopoietic stem cells, which can give rise to all blood cells, and endothelial progenitor cells, which repair damage to blood vessels.
April 7, 2010 — (BRONX, NY) — A study of nearly 13,000 rescue workers from the Fire Department of the City of New York (FDNY) shows that the significant proportion who suffered acute lung damage after exposure to World Trade Center (WTC) dust have not recovered normal lung function in the years since the September 11, 2001 terrorist attacks. This seven-year study, with almost 62,000 individual measurements, is the largest longitudinal study ever reported of occupational influences on lung function.
DURHAM, N.C. -- Adding the investigational drug telaprevir to standard treatment for hepatitis C infection cures about half the patients willing to give therapy a second try. That compares to a cure rate of just 14 percent among those who were retreated with the standard regimen, according to researchers at the Duke Clinical Research Institute (DCRI).
Taking vitamin C and E supplements starting in early pregnancy does not reduce the risk for the hypertensive disorders and their complications that occur during pregnancy, according to a study by a National Institutes of Health research network.
The supplements notably failed to reduce the risk of preeclampsia, a potentially fatal form of hypertension in pregnancy. The findings are in contrast to suggestions in some previous small studies that the vitamins could reduce the risk of preeclampsia. Those studies were not confirmed in subsequent larger studies.
PITTSBURGH—An international study based at the University of Pittsburgh provides the first identification of a human enzyme that can biodegrade carbon nanotubes—the superstrong materials found in products from electronics to plastics—and in laboratory tests offset the potentially damaging health effects of being exposed to the tiny components, according to findings published online in Nature Nanotechnology.
Underwater canyons have long been considered important habitats for marine life, but until recently, only canyons on continental margins had been intensively studied.
ST. PAUL, Minn. –A new study shows that smoking may increase the risk of multiple sclerosis (MS) in people who also have specific established risk factors for MS. The research is found in the April 7, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.
NEW YORK (April 7, 2010) – Underscoring what researchers call a serious global public health concern, results from a new study led by Columbia University Medical Center reveal that many women at an elevated level of risk for osteoporosis-associated fractures fail to perceive the implications of the risk factors.
Ann Arbor, Mich. – It was a provocative prediction that due to the obesity epidemic Baby Boomers may outlive their children.
But a new study by the University of Michigan Health System on obesity trends shows Americans are getting heavier younger and carrying the extra weight for longer periods over their lifetime.
As a result, the study suggests the impact on chronic diseases and life expectancy may be worse than previously thought. The findings will be published April 12 in the International Journal of Obesity.
PITTSBURGH—An international study based at the University of Pittsburgh provides the first identification of a human enzyme that can biodegrade carbon nanotubes—the superstrong materials found in products from electronics to plastics—and in laboratory tests offset the potentially damaging health effects of being exposed to the tiny components, according to findings published online in Nature Nanotechnology.