Body

LA JOLLA, CA – April 19, 2010 – Scientists from The Scripps Research Institute have provided an answer to the 40-year-old mystery of how certain genetic mutations lead to Type 1 diabetes. This new molecular understanding could lead to novel therapies for Type 1 diabetes and other autoimmune diseases.

The study was published in an advanced, online issue of the Journal of Clinical Investigation on April 19, 2010, and will appear in the May print edition of the journal.

It's not enough that you have to feel guilty for having children, since is is possible they could have been a victim of third-hand smoke or Crème brûlée during your pregnancy, now a study claims eating too much fat may impact your grandchildren as well.

PORTLAND, Ore. – A simple blood test can identify people who are at risk for a heart attack, including thousands who don't have high cholesterol, according to researchers at Oregon Health & Science University.

WASHINGTON, D.C. — Statins did not protect patients against colorectal adenomas, which are benign precursors of colorectal cancer, according to results of a secondary analysis of the Adenoma Prevention with Celecoxib (APC) trial. In a population at high-risk for developing these lesions, results of this analysis suggested statin use may increase the risk of developing benign colorectal tumors.

When both cancer and benign diagnoses are taken into consideration, patients undergoing colon surgery appear to have increased odds of death if their procedure is performed at a teaching hospital, according to a report in the April issue of Archives of Surgery, one of the JAMA/Archives journals.

Follow-up visits conducted via a secure Web site may result in similar clinical outcomes as in-person visits among patients with acne, according to a report in the April issue of Archives of Dermatology, one of the JAMA/Archives journals.

Patients who receive an audiotape of their consultation before undergoing heart surgery appear to have more knowledge about their procedures and their health, and also have reduced anxiety and depression, according to a report in the April issue of Archives of Surgery, one of the JAMA/Archives journals.

Individuals who are exposed to more secondhand smoke in private and public settings appear more likely to have chronic rhinosinusitis, according to a report in the April issue of Archives of Otolaryngology–Head & Neck Surgery, one of the JAMA/Archives journals.

Cases of foreign bodies obstructing the airways of young children occur infrequently, but the death rate from such events is high, according to a report in the April issue of Archives of Otolaryngology–Head & Neck Surgery, one of the JAMA/Archives journals.

A Henry Ford Health System study has linked nearly 40 percent of chronic rhinosinusitis diagnoses to secondhand smoke. Chronic rhinosinusitis, or CRS, is a form of sinusitis in which the moist tissues of the nose and paranasal sinuses are inflamed for at least 12 weeks.

Researchers found that people are at increased risk for developing rhinosinusitis from exposure to secondhand smoke at home and public places like bars and restaurants, but that the risk is even higher at work and at private social settings.

"Bureaucracy is the death of all sound work," said Albert Einstein, sharing a popular view about bureaucracy grinding progress to a halt.

WASHINGTON, D.C. — Metformin, a mainstay of treatment for patients with type 2 diabetes, may soon play a role in lung cancer prevention if early laboratory research presented here at the AACR 101st Annual Meeting 2010 is confirmed in clinical trials.

Metformin decreases levels of insulin-like growth factor-1 (IGF-1) and circulating insulin, which is important in patients with type 2 diabetes. However, emerging research suggests metformin may inhibit tumor growth as well.

Montreal, April 19, 2010 – Low back pain (or lumbago) is a common ailment often triggered by something as simple as lifting a suitcase. What is the best way to remedy the situation? An exercise machine designed specifically for back muscles could be the solution according to a new study published in the Journal of the American College of Sports Medicine.

ANN ARBOR, Mich. — A genetic test can help determine in which patients cholesterol-lowering statin drugs might have the most benefit in also reducing the risk of colorectal cancer, a new study from researchers at the University of Michigan Comprehensive Cancer Center finds.

RICHMOND, Va. (April 19, 2010) – Virginia Commonwealth University researchers have identified a new tumor-promoting gene that may play a key role in the development of liver cancer. Levels of the gene's expression are significantly higher in more than 90 percent of patients with the disease compared to their healthy counterparts.