Body

Type 2 diabetes is a widespread problem for many people these days, and our risk for insulin resistance and diabetes only grows as we age. Now, a new report in the May issue of Cell Metabolism, a Cell Press publication, reveals a new contributor to the problem: The muscles of elderly people and of people with type 2 diabetes contain lower concentrations of a protein known as PARL (short for "presenilin-associated rhomboid-like").

CINCINNATI—The popular diabetes medication metformin works in different fashion than the current widely accepted view. This new finding could lead to wider use of the drug—particularly in people with cancer and diseases linked to TSC deficiency like tuberous sclerosis and lymphangioleiomyomatosis (LAM).

The results of this study, led by George Thomas, PhD, scientific director of UC's Metabolic Diseases Institute, are published in the May 5 edition of Cell Metabolism.

URBANA – New treatments for intestinal failure and other intestinal absorption disorders are a step closer to the patients who need them after a discovery in Kelly Tappenden's University of Illinois laboratory.

NEW ORLEANS, LA (May 4, 2010) – Rates of colorectal cancer screening vary by race and ethnicity as well as method, according to data being presented at Digestive Disease Week® (DDW®) 2010. Scientists examine data on minority and older populations as well as utilization rates of virtual and optical colonoscopies to better understand adherence to recommended screening guidelines. DDW is the largest international gathering of physicians and researchers in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

The UK trawl fishing fleet has to work 17 times harder to catch the same amount of fish today as it did when most of its boats were powered by sail, according to new research.

Researchers from the University of York and the Marine Conservation Society (MCS) used UK Government data on the amount of fish caught and the size and number of boats involved – the fleet's fishing power – to analyse the change in fish stocks since 1889.

GAINESVILLE, Fla. --- Call it Nitelite: The newest app for cell phones might be night vision.

A University of Florida engineering researcher has crafted a nickel-sized imaging device that uses organic light-emitting diode technology similar to that found in cell phone or laptop screens for night vision. But unlike night vision goggles, which are heavy and expensive, the device is paper-thin, light and inexpensive, making it a possible add-on to cell phone cameras, even eyeglasses, once it is enlarged.

(PHILADELPHIA) – Researchers at Thomas Jefferson University have found that colonoscopy preparation drugs administered the same day as the procedure are equally effective to those given the night before and the morning of the procedure, but result in less complaints of side effects such as abdominal pain, sleep loss and workday interference.

New Orleans, LA – Researchers at LSU Health Sciences Center New Orleans and Children's Hospital of New Orleans have found that there is a major difference in the hemoglobin A1c (HbA1c) response to blood glucose between African-American and Caucasian children with diabetes. HbA1c is the main test used to monitor diabetes and guide treatment decisions. African-American children test significantly higher than Caucasians who have similar average blood glucose levels. The research may explain why African Americans are at increased risk of diabetes complications.

May 3, 2010 -- A study by researchers at Columbia University's Mailman School of Public Health suggests that traumatic experiences "biologically embed" themselves in select genes, altering their functions and leading to the development of post-traumatic stress disorder (PTSD).

Natural selection for moderate testosterone surprises scientists

BLOOMINGTON, Ind. -- A field study of the relationship between testosterone and natural selection in an American songbird, the dark-eyed junco, has defied some expectations and confirmed others.

Glaucoma's unique protein expression could enhance diagnosis and treatment

AUGUSTA, Ga. - An eye under pressure appears to express a unique set of proteins that physicians hope will one day help them better diagnose and treat glaucoma.