Body
Researchers at Mount Sinai School of Medicine have developed a new gene therapy that is safe and effective in reversing advanced heart failure. SERCA2a (produced as MYDICAR®) is a gene therapy designed to stimulate production of an enzyme that enables the failing heart to pump more effectively. In a Phase II study, SERCA2a injection through a routine minimally invasive cardiac catheterization was safe and showed clinical benefit in treating this patient population and decreasing the severity of heart failure.
EVANSTON, Ill. --- The hunting strategy of a slender fish from the Amazon is giving researchers more insight into how to balance the metabolic cost of information with the metabolic cost of moving around to get that information.
A new study from Northwestern University's McCormick School of Engineering and Applied Science answers the question: In behaviors in which you have to move to get information, when should the animal spend more energy on locomotion versus spending more energy on getting more information?
Every minute, 10,000 gallons of water mysteriously gush out of the desert floor at a place called Ash Meadows, an oasis that is home to 24 plant and animal species found nowhere else in the world.
A new Brigham Young University study indicates that the water arriving at Ash Meadows is completing a 15,000-year journey, flowing slowly underground from what is now the Nevada Test Site.
The U.S. government tested nuclear bombs there for four decades, and a crack in the Earth's crust known as the "Gravity Fault" connects its aquifer with Ash Meadows.
Hamilton, ON (June 3, 2010) – McMaster University researchers have discovered a central controller or processing unit (CPU) of a superbug's weaponry.
An article on the breakthrough appears in the high-impact journal Science today.
The team from the Michael G. DeGroote Institute for Infectious Disease Research has revealed that a small chemical, made by the superbug Staphylococcus aureus and its drug-resistant forms, determines this disease's strength and ability to infect.
A new therapy mounts a double-barreled attack on leukemia, targeting not just the cancer cells but also the environment in which those cells live and grow, University of Florida researchers report.
Like striking an enemy camp directly as well as cutting off its source of food and other resources, the agent, called Oxi4503, poisons leukemia cells and destroys the blood vessels that supply them with oxygen and nutrients.
Professor Wang Yun Cai and his student Wang An Bang reported a new concept of optical time domain reflectometry (OTDR) based on a chaotic light correlation method. This will be useful for precise fault location in fiber links with high-density events. Their work is reported in Issue 53 (February, 2010) of SCIENCE CHINA Information Sciences.
In recent years, the Internet has been evolving from a primarily publication platform to a user participatory platform. With the proliferation of services available on the Internet, millions of users are able to voluntarily participate in the development of their own interests and benefits by means of service composition. However, due to the ever increasing number of services, enabling users to rapidly select and access these services has become a challenging issue.
Tracing the success of individual wild insects in leaving descendants is now possible according to new research by University of Exeter biologists using a combination of digital video technology, tagging and DNA fingerprinting.
PASADENA, Calif.—Biologists at the California Institute of Technology (Caltech) have pinpointed molecular changes that helped allow the global spread of resistance to the antiviral medication Tamiflu (oseltamivir) among strains of the seasonal H1N1 flu virus.
The study—led by David Baltimore, Caltech's Robert Andrews Millikan Professor of Biology and recipient of the 1975 Nobel Prize in Physiology or Medicine, and postdoctoral scholar Jesse D. Bloom—appears in the June 4 issue of the journal Science.
PITTSBURGH, June 3 – The liver scarring of α1-antitrypsin (AT) deficiency, the most common genetic cause for which children undergo liver transplantation, might be reversed or prevented with a medication that has long been used to treat seizures, according to findings from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine that will published in Science and are available online today through the Science Express website.
Biosensors reveal how single bacterium gets the message to split into a swimming and a stay-put cell
Some species of bacteria perform an amazing reproductive feat. When the single-celled organism splits in two, the daughter cell - the swarmer - inherits a propeller to swim freely. The mother cell builds a stalk to cling to surfaces.
ST. LOUIS -- While researchers have done a good job documenting health problems associated with the high prevalence of smoking among Americans who have HIV/AIDS, it's now time to focus on how to get these smokers to kick the habit, Saint Louis University School of Public Health research finds.
Of the 1.1 million Americans living with HIV/AIDS, between 40 and 60 percent are smokers – which is two to three times the rate of smokers in the general population.
Researchers at Mount Sinai School of Medicine have discovered a novel component of the influenza virus that may be the key to disabling the virus's ability to replicate itself and to developing a universal anti-viral treatment. The findings were published June 1 online in Proceedings of the National Academy of Sciences.
The delicate balance of microbes in the vagina can vary greatly between healthy women, according to a new study led by the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers hope further study will lead to personalized reproductive medicine for women, allowing doctors to tailor each woman's treatment and health maintenance strategies to her individual microbial make-up.