Body

Researchers from the University of Illinois at Chicago have discovered that an unexpected cellular response plays an important role in breaking down and inhibiting the formation of excess scar tissue in wound healing.

Their study was published online this week in Nature Cell Biology.

WEST LAFAYETTE, Ind. - Isolating a gene that allows a type of fern to tolerate high levels of arsenic, Purdue University researchers hope to use the finding to create plants that can clean up soils and waters contaminated by the toxic metal.

The fern Pteris vittata can tolerate 100 to 1,000 times more arsenic than other plants. Jody Banks, a professor of botany and plant pathology, and David Salt, a professor of horticulture, uncovered what may have been an evolutionary genetic event that creates an arsenic pump of sorts in the fern.

By tinkering with a type of fungus that lives in association with plant roots, researchers have found a way to increase the growth of rice by an impressive margin. The so-called mycorrhizal fungi are found in association with nearly all plants in nature, where they deliver essential nutrients—specifically phosphate—to plants in return for sugar.

Dar es Salaam, 10 June 2010 - As Kenya once again grapples with high levels of aflatoxin contamination, which has rendered at least 2.3 million bags of maize unfit for human and livestock consumption, international experts announced today that they have identified a local non-toxic form of the fungus responsible for aflatoxin that can be used to control contamination through a novel biological control approach, which is entirely safe and effective.

Diabetes may double cancer risk in women

Type 2 adult-onset diabetes causes insulin-like hormones to circulate through the body. A new study finds this has a surprisingly positive effect on reducing the rate of prostate cancer in men, but is bad news for women: Type 2 diabetes may double the risk of female genital and other cancers.

INDIANAPOLIS -- The combination of decitabine and carboplatin appears to improve the outcome of women who have late-stage ovarian cancer. In an upcoming issue of the journal Cancer (online today), Indiana University researchers report four of 10 patients who participated in a phase I clinical trial had no disease progression after six months of treatment. One patient experienced complete resolution of tumor tissue for a period of time.

A research team led by Dr. Nada Jabado at the MUHC and Dr. Jacek Majewski at McGill University has proven for the first time that it is possible to identify any genetic disease in record time thanks to a powerful and reliable exome sequencing method. The exome, a small part of the genome (< 2%), is of crucial interest with regard to research on genetic diseases as it accounts for 85% of mutations. The results of the team's research have just been published in the journal Human Mutation.

Scientists have uncovered the flu's secret formula for effectively evolving within and between host species: balance. The key lies with the flu's unique replication process, which has evolved to produce enough mutations for the virus to spread and adapt to its host environment, but not so many that unwanted genomic mutations lead to the flu's demise (catastrophic mutagenesis). These findings overturn long-held assumptions about how the virus evolves.

Made popular for its ability to smooth wrinkles when injected into the face, Botox — a toxin known to weaken or paralyze certain nerves and muscles — may have another use that goes beyond the cosmetic.

Johns Hopkins researchers have found that patients with a painful and debilitating nerve compression disorder called thoracic outlet syndrome (TOS), which studies suggest may occur in up to 8 percent of the population, reported a significant reduction in short-term pain after receiving a single, low-dose injection of Botox in a muscle located in the neck.

Storm elves and sprites recorded on video

A team of Spanish researchers has made a high-speed recording of elves and sprites in storms, fleeting and luminous electric phenomena produced in the upper layers of the atmosphere. Their analysis of these observations has been published in the Journal of Geophysical Research.

Collagen manufactured from transgenic tobacco plants at Hebrew University

Jerusalem, June 10, 2010 – A scientist at the Hebrew University of Jerusalem's Robert H. Smith Faculty of Agriculture, Food and Environment has succeeded in producing a replica of human collagen from tobacco plants – an achievement with tremendous commercial implications for use in a variety of human medical procedures.

Protein p53 is known as the guardian of the genome since it is basic for the genome's integrity by preventing the accumulation of mutations originating either by the cell's own mechanisms or by the action of external agents. The protein becomes activated in response to specific signals such as breaks in DNA. This activation implies a slowing of the cell's cycle which allows it to repair itself from the damage. If the damage is not repaired on time, the activation of p53 results in programmed cell death known as apoptosis.