By unlocking the genetic secrets of sorghum, Agricultural Research Service (ARS) scientists have found a way to make one of the world's most important cereal crops a better option for growers. Researchers at the ARS Natural Products Utilization Unit in Oxford, Miss. also may have opened a door to reducing pesticide use in the production of other crops.
Leaded gasoline was responsible for about two-thirds of toxic lead that African-American children in Cleveland ingested or inhaled during the latter two-thirds of the 20th century, according to a new study in Science of the Total Environment.
The degradation of proteins and other macromolecules in cells is vital to survival. Disruption of this process can result in serious disease. The research group of Professor Thomas Jentsch (Leibniz Institute for Molecular Pharmacology, FMP/ Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch) has now succeeded in identifying an essential cellular process necessary for the transport and degradation of macromolecules in endosomes and lysosomes, respectively.
PHILADELPHIA — Combined targeted therapy against the BRAF/MAPK pathway with immunotherapy shows promise as a new therapeutic approach for the treatment of melanoma, according to results of a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.
PHILADELPHIA — Preclinical findings recently published in Cancer Research, a journal of the American Association for Cancer Research, showed RG7204 (PLX4032) inhibited proliferation of tumor cell lines that expressed V600E-BRAF, a mutation found in several human cancers, including melanoma.
The compound also showed partial or complete tumor regression and improved survival in a dose-dependent manner in preclinical efficacy models in rodents, without associated toxicity.
RESTON, Va. - SNM's 2010 Image of the Year illustrates the potential of hybrid molecular imaging to provide precise information about the location and function of a condition known as "hyperparathyroidism." Researchers selected this image from more than 1,500 studies presented over the course of four days during SNM's 57th Annual Meeting in Salt Lake City.
A hormone that helps to regulate blood sugar levels may also influence a person's sensitivity to sweet-tasting foods, according to a new study from researchers at the University of Maryland School of Medicine. They found that blocking the tongue's ability to respond to the hormone known as glucagon decreases the taste system's sensitivity to sweetness. That is, changing the actions of the hormone glucagon could control how foods taste, according to the study published online June 14 in the Federation for American Societies for Experimental Biology (FASEB) Journal.
ARGONNE, Ill. (June 15, 2010) — A scientist at the U.S. Department of Energy's (DOE) Argonne National Laboratory has created visible-light catalysis, using silver chloride nanowires decorated with gold nanoparticles, that may decompose organic molecules in polluted water.
The June edition of the Journal of Thoracic Oncology features a study aimed at determining the optimal dose of the chemotherapy drug nab-paclitaxel with carboplatin as a first-line therapy in patients with non-small cell lung cancer (NSCLC). Results will provide researchers with a data needed to guide a phase 3 trial.
Montreal, June 15, 2010 – Canadian researchers have discovered a new way the body combats respiratory viral infections. In the prestigious journal PLoS Pathogens, scientists from the University of Montreal and the University of Montreal Hospital Research Center explain how the NOX2 molecule, an enzyme that generates a burst of highly reactive oxygen derivatives (or free radicals), activates defense genes and molecules when viruses invade lung cells.
Are voters truly sophisticated and rational decision makers? Apparently not. Their choices are heavily influenced by superficial, nonverbal cues, such as politicians' appearance, according to Christopher Olivola from University College London in the UK and Alexander Todorov from Princeton University in the US. According to their findings1, voters make judgments about politicians' competence based on their facial appearance and these appearance-based competence judgments reliably predict both voting decisions and election outcomes.
Doctors at the University Heart Center in Hamburg, Germany successfully used transcatheter valve-in-valve implantation in elderly patients with degenerated bioprostheses in aortic and mitral position. This minimally invasive procedure was used as an alternative treatment option for patients who were at high surgical risk. Full details of the study are available in the June issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions.
Strict milk quality tests had drawn a national attention throughout China in the wake of the baby formula milk powder contamination incident. The individual classic markers for milk quality control, particularly protein concentration, are easy to be manipulated and it is difficult to use these markers to monitor the raw milk content in formula milk and various milk products. The findings, published this week in Cell Research, could lead to a completely new standard for milk quality control, and possible new milk products with specific usage in the future.
A UC researcher proposes that taste is in the tongue of the beholder when it comes to vodka.
University of Cincinnati Professor Dale W. Schaefer, in the Chemical and Materials Engineering Department of UC's College of Engineering and Applied Science, is part of an international team of scientists studying to see if there is a scientific way to measure structure in vodkas. UC collaborated with scientists from Moscow State University.
