Body

Rome, Italy, Friday 18 June 2010: There is significant disparity between 'richer' and 'poorer' countries in terms of access to biological treatments for rheumatoid arthritis (RA), according to results from a multinational study across four continents presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. Furthermore, findings from a separate study show that RA patients report the severity of their disease in the same way, irrespective of the country where they live.

Competition puts the brakes on body evolution in island lizards

Durham, NC – Millions of years before humans began battling it out over beachfront property, a similar phenomenon was unfolding in a diverse group of island lizards.

An international team of researchers, led by the members of the Institut de Ciència i Tecnologia Ambientals (ICTA) at the Universitat Autònoma de Barcelona (UAB), has published the first registers of the evolution of Northern Pacific and Southern Atlantic sea-surface temperatures, dating from the Pliocene Era -some 3.65 million years ago- to the present. The data obtained in the reconstruction indicate that the regions closer to the poles of both oceans have played a fundamental role in climate evolution in the tropics.

Corals right out on the exposed edges of the world's great coral reef zones may hold an important clue to the survival of coral ecosystems facing intensifying pressure from human activities and climate change.

Rome, Italy, Friday 18 June: The expression of a transporter protein called the Breast Cancer Resistance Protein (BCRP) in rheumatoid arthritis (RA) patients may indicate higher disease activity and could be a barrier to the effectiveness of disease-modifying antirheumatic drugs (DMARDs), according to the results of a study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

KNOXVILLE -- By examining 800,000-year-old polar ice, scientists increasingly are learning how the climate has changed since the last ice melt and that carbon dioxide has become more abundant in the Earth's atmosphere.

More than five tonnes of illegal bushmeat is being smuggled in personal luggage each week through one of Europe's busiest airports, reveals new research published in Conservation Letters today.

Working alongside customs officials at France's Roissy-Charles de Gaulle airport, researchers from the Zoological Society of London (ZSL), The Royal Veterinary College (RVC) and The National Veterinary School and the Natural History Museum of Toulouse identified eleven bushmeat species from confiscated luggage, including species of primate, crocodiles and pangolins.

Using new, whole-genome sequencing technology coupled with classic methods of genetic investigation, scientists at Duke University, along with colleagues at Johns Hopkins, have discovered two mutations in the same gene that seem to cause metachondromatosis in humans. This is a rare, heritable disease that leads to bony growths, mostly on the hands and feet.

Discovery of a key red cell molecule used by the malaria parasite gives renewed hope for an effective vaccine in the future, according to an international team of researchers.

Plasmodium falciparum, a blood parasite that causes malaria by invading and multiplying in the red blood cells, kills 1 to 2 million people annually.

DURHAM, N.C. – Combining new, whole-genome sequencing technology with classic genetic approaches to understanding inherited diseases, Duke University Medical Center geneticists and colleagues at Johns Hopkins have discovered two gene mutations that cause metachondromatosis, a rare, heritable disorder that leads to bony growths, typically on hands and feet.

They did it by sequencing the entire genome of just one individual.

Caribbean coral reef protection efforts miss the mark

Conservation efforts aimed at protecting endangered Caribbean corals may be overlooking regions where corals are best equipped to evolve in response to global warming and other climate challenges.

Virginia Commonwealth University researchers have discovered a mechanism by which an enzyme regulates gene expression and growth in melanoma cells, a finding that could someday lead to more effective drugs to attack cancers and make them more treatable.

STANFORD, Calif. — Web sites that promote anorexia and bulimia offer interactive communities where site users can encourage one another in unhealthy eating behaviors, yet the majority of these sites also recognize eating disorders as a disease, according to new research from the Johns Hopkins Bloomberg School of Public Health and the Stanford University School of Medicine.