Body

BIRMINGHAM, Ala. – Children who are being treated for hearing loss with cochlear implants can safely have ear tubes installed to help clear up infections, say researchers at the University of Alabama at Birmingham (UAB).

Exposure to high levels of fungus may increase the risk of severe asthma attacks among people with certain chitinase gene variants, according to a study from Harvard Medical School, Harvard Pilgrim Health Care Institute and Brigham and Women's Hospital.

The research was published online on the American Thoracic Society's journal Web site ahead of the print edition of the American Journal of Respiratory and Critical Care Medicine.

Disease-modifying antirheumatic drugs (DMARDs) should be used early and aggressively at the first sign of rheumatoid arthritis (RA). The results of an 11-year trial, published in BioMed Central's open access journal Arthritis Research & Therapy, demonstrate that active treatment from the very beginning pays off, even in the long run.

Swingers - straight couples who regularly swap sexual partners at organised gatherings and clubs and indulge in group sex - have rates of sexually transmitted infections comparable with those of recognised high risk groups, reveals research published ahead of print in the journal Sexually Transmitted Infections.

Those who are over the age of 45 are particularly vulnerable, indicates the research, yet swingers are largely ignored by healthcare services, representing a "missed target," say the authors.

A vaccine-derived strain of poliovirus that has spread in recent years is serious but it can be tackled with an existing vaccine, according to a new study published today in the New England Journal of Medicine.

Vaccine-derived polioviruses can emerge on rare occasions in under-immunised populations, when the attenuated virus contained in a vaccine mutates and recombines with other viruses, to create a circulating vaccine-derived strain.

June 23, 2010 – Between 33 and 77 million people in Bangladesh have been exposed to arsenic in the drinking water—a catastrophe that the World Health Organization has called "the largest mass poisoning in history." A new study published in the current issue of the medical journal The Lancet provides the most complete and detailed picture to date of the high mortality rates associated with this exposure, which began with the widespread installation of tube wells throughout the country 30 years ago—a measure intended to control water-bourne diseases.

ST. PAUL, Minn. –A group of tests may help predict which people with Parkinson's disease are more likely to fall, according to a study published in the June 23, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Underinsured African-Americans had worse breast cancer survival outcomes than underinsured non-Hispanic whites, according to a study published online June 23rd in the Journal of the National Cancer Institute.

To predict atherosclerosis, follow the disturbed blood flow

A new animal model of atherosclerosis has allowed researchers to identify a host of genes turned on or off during the initial stages of the process, before a plaque appears in the affected blood vessel.

The results were published June 15 in Blood, the journal of the American Society of Hematology.

BOSTON -- A central tenet of molecular biology, as proposed in 1970 by Francis Crick and James Watson, holds that genetic information is transferred from DNA to functional proteins by way of messenger RNA (mRNA). This suggests that mRNA has but a single role, that being to encode for proteins. A cancer genetics team at Beth Israel Deaconess Medical Center (BIDMC) suggests there is much more to RNA than meets the eye.

New method of peptide synthesis makes it easier to create drugs based on natural compounds

A team of Vanderbilt chemists has developed a novel method for chemically synthesizing peptides that promises to lower the cost and increase the availability of drugs based on natural compounds.

Researchers from Mount Sinai School of Medicine have found why patients with a variant form of xeroderma pigmentosum (XPV), an inherited genetic disorder characterized by extreme sensitivity to the sun, are more susceptible to skin cancers than the general population. The data are published in the current issue of the journal Nature. Their finding sets the stage for research into therapies that would help protect people with XPV from developing skin cancers.

DALLAS – June 23, 2010 – Researchers at UT Southwestern Medical Center have pinpointed a set of biological mechanisms through which estrogen confers its beneficial effects on the cardiovascular system, independent of the hormone's actions on cancer. Their investigation suggests that drugs targeting a specific subpopulation of estrogen receptors found outside the cell nucleus might activate the cardiovascular benefits of estrogen without increasing cancer risk.