Human embryonic stem cells hold great promise for studying and treating disease and for the practice of regenerative medicine. However, more must be learned to ensure the cells that may one day be transplanted into humans are safe.
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International team of Italy-US scientists reports discovery of a new mechanism of avian influenza virus circulation and transmission in nature
Why are tropical forests so biologically rich? Smithsonian researchers have new evidence that the answer to one of life's great unsolved mysteries lies underground, according to a study published in the journal, Nature.
A mechanism that regulates stem-cell differentiation in mice testes suggests a similar process that may trigger degenerative disease in humans, according to a Penn State College of Agricultural Sciences reproductive physiologist.
Research involved manipulating a protein called STAT3 that signals stem cells to decide whether to differentiate into a specialized type of cell or self-renew and remain stem cells. By manipulating STAT3, researchers identified a key regulator of spermatogonial stem cell self-renewal.
MILWAUKEE – What determines plant diversity in a forest? It's a question even Charles Darwin wanted to unravel. But most research into forest diversity demonstrates only patterns of species survival and abundance rather than the reason for them – until now.
A team of researchers led by biologists at the University of Wisconsin–Milwaukee (UWM) has shown that soil-borne pathogens are one important mechanism that can maintain species diversity and explain patterns of tree abundance in a forest.
NEW YORK, June 24, 2010—A unique collaboration among physician-scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) has yielded the most comprehensive genomic analysis of prostate cancer to date. "Genomic studies in other cancer types have resulted in new drug targets and strategies to classify patients into clinically meaningful subgroups that improve treatment decisions," said senior study author Charles Sawyers, Chair of the Human Oncology and Pathogenesis Program at MSKCC and a HHMI investigator.
Between 1998 and 2007, psychotropic medications were associated with 429 adverse drug reactions in Danish children under the age of 17. Researchers from the University of Copenhagen's Faculty of Pharmaceutical Studies have published an article in the open access journal BMC Research Notes concluding that more than half of the 429 cases were serious and several involved birth defects, such as birth deformities and severe withdrawal syndromes.
Cold Spring Harbor, N.Y. – One way of regulating protein levels in cells is to shorten the lifespan of messenger RNAs (mRNAs). These are intermediary molecules that are first copied from DNA in the cell's nucleus via a process called transcription and then transported into the cell's body to be translated into protein.
London, 25 June, 2010 - New research, published by Elsevier in the Royal Society for Public Health's journal Public Health, provides compelling evidence that deprivation alone cannot explain the poor health experienced by Glasgow's residents.
People who fish for a living pursue top profits, not necessarily top predators, according to the first-ever analysis of worldwide catch and economic data for the past 55 years.
This differs from the observation raised 10 years ago that humans were "fishing down" the food web. It was assumed that catches of the predators at the top of the food chain, such as halibut and tuna, were declining after fishers started landing more fish from lower on the food chain, such as herring and anchovies.
St Louis, MO – Current research suggests that resveratrol, a naturally occurring compound found in red wine, grapes, blueberries, peanuts, and other plants, inhibits pathogenic new blood vessel growth. The related report by Khan et al, "Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase regulated pathway," appears in the July 2010 issue of The American Journal of Pathology.
New York, New York, June 25, 2010 – Cardiac allograft vasculopathy (CAV), the major limitation to long term survival after heart transplantation, occurs when blood vessels in a transplanted heart progressively narrow and lead to dysfunction of the heart muscle or sudden death. Ascertaining benefit from appropriate treatment for this condition has been hampered in part because of the lack of a standard nomenclature.