Body
LOS ANGELES (September 7, 2010) – The first study to demonstrate that obesity can directly accelerate the progression of acute lymphoblastic leukemia (ALL) has been conducted at The Saban Research Institute of Childrens Hospital Los Angeles and will be published in Cancer Prevention Research, on October 5, 2010. Obesity has been associated with an increased incidence of many cancers, including leukemia, but it has been unknown whether the increase in incidence was a direct effect of obesity or associated with genetic, lifestyle, health, or socio-economic factors.
Obesity and infertility frequently go hand in hand. Now, researchers reporting on studies of mice in the September issue of Cell Metabolism, a Cell Press publication, might have figured out why that is, and the results come as something of a surprise.
New findings reported in the September issue of Cell Metabolism, a Cell Press publication, appear to explain why people who carry specific and common versions of a single gene are more likely to have high cholesterol and to suffer a heart attack. Studies in mice show that the gene, known as sortilin (SORT1), controls the release of LDL (a.k.a. "bad") cholesterol from the liver into the bloodstream.
The findings suggest that SORT1 may be a good target for new cholesterol-lowering drugs, according to the researchers.
In children with wrist fractures, a splint is as effective as a cast and provides greater comfort and easier hygiene, found a study published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100119.pdf.
Distal radius fractures — wrist fractures — are the most common break in children and a frequent reason for emergency department visits. The usual treatment is a short arm cast for four to six weeks with follow up visits to an orthopaedic surgeon.
Researchers at the Buck Institute for Age Research have discovered a novel way in which insulin affects cell metabolism and cell survival. Surprisingly the insulin signaling pathway, which is involved in aging, diabetes and stress response, is active at a deeper level of cell activity than scientists expected. The study appears in the September 8th issue of Cell Metabolism.
Obese women have a well-known risk for infertility, but a new Johns Hopkins Children's Center study has unraveled what investigators there believe is the mechanism that accounts for the risk.
St. Louis, MO – Current research provides a novel model for rheumatoid arthritis research. The related report by LaBranche et al, "Characterization of the KRN cell transfer model of rheumatoid arthritis (KRN-CTM), a chronic yet synchronized version of the K/BxN mouse," appears in the September 2010 issue of The American Journal of Pathology.
COLUMBIA, Mo. – With the fragmentation and globalization of the U.S. textile and apparel industry, business activities and roles have changed, impacting their organizational identity. The evolving organizational identity of these firms has created many questions as to how it affects the businesses financially. Now, a researcher at MU has explored how U.S. textile and apparel firms describe themselves as organizations and how those descriptions compare to U.S.
The Potomac River in Washington, D.C. is showing multiple benefits from restoration efforts, newly published research suggests. Reduced nutrients and improved water clarity have increased the abundance and diversity of submerged aquatic vegetation (SAV) in the Potomac, according to direct measurements taken during the 18-year field study.
PHILADELPHIA, PA. (September 7, 2010)—Aurora-A kinase (AurA) is an enzyme that is hyperactive in many cancers and drives tumor cell proliferation. Several AurA inhibitors are currently being tested in clinical trials to see if they slow tumor growth. Now, researchers in the Developmental Therapeutics Program at Fox Chase Cancer Center have identified an activation signal for AurA. They report in the September 7 issue of Nature Communications that a quick increase in the calcium concentration in a cell rapidly triggers AurA kinase activity.
People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers at the University of Warwick.
A study by a team of researchers from Warwick Medical School and the State University of New York at Buffalo has found short sleep duration is associated with an elevated risk of a pre-diabetic state, known as incident-impaired fasting glycaemia (IFG).
CHICAGO (September 7, 2010) – Obese women who have bariatric surgical procedures before pregnancy were three times less likely to develop gestational diabetes (GDM) than women who have bariatric operations after delivery, according to new research findings published in the August issue of the Journal of the American College of Surgeons. The retrospective study also found that delivery after bariatric procedures was associated with reduced odds of cesarean section—an outcome associated with GDM.
CHICAGO (September 7, 2010) – Penetrating injury rates were more than 20 times higher for persons living in the lowest income neighborhoods compared with those living in the highest income neighborhoods, according to a new study published in the August issue of the Journal of the American College of Surgeons. Researchers also found that those in the lowest-income neighborhoods experienced nearly six times higher rates of blunt injury than persons in the highest income neighborhoods.
Plants cannot thrive without nutrients such as nitrogen, phosphorous or potassium, therefore farmers usually use organic and industrially manufactured mineral fertilizers to supply wheat, maize and others with these vital substances. In future, the need for nutrients will be soaring because we will only be able to supply the world's growing population with food and cover surging demands for biofuels by using fertilizers. Logically, that causes the prices for these nutrients to skyrocket. But that is not the only problem.