Body

CINCINNATI – Using fruit flies as a model to study embryo formation, scientists report in Nature Cell Biology that molecular breakdown of a protein called Bicoid is vital to normal head-to-tail patterning of the insect's offspring.

Reading 'Avatar''s DNA

Tel Aviv -- You know when you're watching a pirated film downloaded from the Internet -- there's no mistaking the fuzzy footage, or the guy in the front row getting up for popcorn. Despite the poor quality, pirated video is a serious problem around the world. Criminal copyright infringement occurs on a massive scale over the Internet, costing the film industry -- and the U.S. economy -- billions of dollars annually.

(Boston) – Researchers from Boston University School of Medicine (BUSM) have demonstrated that certain T cells require input from monocytes in order to maintain their pro-inflammatory response in people with type 2 diabetes (T2D). The study also showed, for the first time, how a loss in homeostasis in this group of T cells most likely promotes chronic inflammation associated with T2D.

COLUMBUS, Ohio – The language that doctors use with low-income, rural patients can help determine whether these patients agree to participate in clinical trials testing new cancer treatments, a new study found.

Researchers found that the metaphors doctors used to help explain what happens in such trials played a big role in whether patients would agree to participate.

MERCED, Calif. — The prolonged, extensive emission of greenhouse gases over the next several decades could have significant impacts on ocean life, according to a study by UC Merced marine biologist Michael Beman.

Increases in carbon dioxide emissions — exacerbated by the burning of fossil fuels and other human activities — are making ocean water more acidic, and Beman's study shows that the increased acidity will fundamentally alter the way nitrogen cycles throughout the sea.

Strictly controlling the heart rate of patients with atrial fibrillation provides no advantage over more lenient heart rate control, experts report in a focused update of the 2006 guidelines for the management of patients with atrial fibrillation.

STANFORD, Calif. — An expanded U.S. program of HIV screening and treatment could prevent as many as 212,000 new infections over the next 20 years and prove to be very cost-effective, according to a new study by Stanford University School of Medicine researchers.

The researchers found that screening high-risk people annually and low-risk people once in their lifetimes was a worthwhile and cost-effective approach to help curtail the epidemic. The screening would have to be coupled with treatment of HIV-infected individuals, as well as programs to help change risky behaviors.

Boston, MA – Scientists at the Harvard School of Public Health (HSPH) and collaborators from other institutions have identified a natural substance in dairy fat that may substantially reduce the risk of type 2 diabetes. The compound, trans-palmitoleic acid, is a fatty acid found in milk, cheese, yogurt, and butter. It is not produced by the body and so only comes from the diet.

Black patients with early-stage liver cancer appear more likely to die of the disease than Hispanic or white patients with the same condition, according to a report in the December issue of Archives of Surgery, one of the JAMA/Archives journals.

Individuals with psoriasis have a high prevalence of the metabolic syndrome, according to a report posted online today that will appear in the April 2011 print issue of Archives of Dermatology, one of the JAMA/Archives journals.

Women are more likely to report use of indoor tanning facilities than men, and some characteristics common to indoor tanners differ by sex, according to a report in the December issue of Archives of Dermatology, one of the JAMA/Archives journals. However, few tanners—male or female—mention avoiding tanning beds when asked about ways to reduce skin cancer risk.

Most patients do not have ongoing speaking or swallowing difficulties following combined chemotherapy and radiation treatment for advanced head or neck cancer, but several factors may be associated with worse outcomes in these functions, according to a report in the December issue of Archives of Otolaryngology–Head & Neck Surgery, one of the JAMA/Archives journals.

Patients who have recurrence of oral squamous cell carcinoma tend to do worse if the new cancer appears at the same site early or if it appears in the lymph nodes six months or longer after initial treatment, according to a report in the December issue of Archives of Otolaryngology–Head & Neck Surgery, one of the JAMA/Archives journals.

DURHAM, NC – Most patients with locally advanced head and neck cancers who successfully complete treatment with chemotherapy and radiation manage to do so without losing the ability to speak clearly and swallow comfortably, according to researchers at the Duke Cancer Institute.

"This is good news," said Joseph K. Salama, MD, an assistant professor of radiation oncology at Duke and the corresponding author of the study. "I hope it brings some comfort to newly-diagnosed patients who are understandably worried about what long-term effects treatment might involve."