Body

A SCUBA expedition in Australia and New Zealand to find the rare embryos of an unusual shark cousin enabled American and British researchers to confirm new developmental similarities between fish and mammals.

Study identifies new genetic signatures of breast cancer drug resistance

A new study conducted by Josh LaBaer's research team in the Biodesign Institute at Arizona State University has pinpointed more than 30 breast cancer gene targets ---including several novel genes---that are involved in drug resistance to a leading chemotherapy treatment.

New method takes snapshots of proteins as they fold

People have only 20,000 to 30,000 genes (the number is hotly contested), but they use those genes to make more than 2 million proteins. It's the protein molecules that domost of the work in the human cell. After all, the word protein comes from the Greek prota, meaning "of primary importance."

Lake Erie hypoxic zone doesn't affect all fish the same, study finds

WEST LAFAYETTE, Ind. - Large hypoxic zones low in oxygen long have been thought to have negative influences on aquatic life, but a Purdue University study shows that while these so-called dead zones have an adverse affect, not all species are impacted equally.

AUSTIN, Texas — Growing up poor can suppress a child's genetic potential to excel cognitively even before the age of 2, according to research from psychologists at The University of Texas at Austin.

Half of the gains that wealthier children show on tests of mental ability between 10 months and 2 years of age can be attributed to their genes, the study finds. But children from poorer families, who already lag behind their peers by that age, show almost no improvements that are driven by their genetic makeup.

Researchers at Nationwide Children's Hospital report a gene therapy strategy that improves the condition of a mouse model of an inherited blood disorder, Beta Thalassemia. The gene correction involves using unfertilized eggs from afflicted mice to produce a batch of embryonic stem cell lines. Some of these stem cell lines do not inherit the disease gene and can thus be used for transplantation-based treatments of the same mice.

DURHAM, N.H. – An international team of researchers, including several from the University of New Hampshire, have completed the first DNA sequence of any strawberry plant, giving breeders much-needed tools to create tastier, healthier strawberries. Tom Davis, professor of biological sciences at UNH, and postdoctoral researcher Bo Liu were significant contributors to the genome sequence of the woodland strawberry, which was published last month in the journal Nature Genetics.

An earlier start on diagnosing breast, prostate cancers

Using biological samples taken from patients and state-of-the-art biochemical techniques, a Florida State University researcher is working to identify a variety of "biomarkers" that might provide earlier warnings of the presence of breast and prostate cancers.

UCLA researchers have found that a protein that plays an important role in some antioxidant therapies may not be as effective due to additional mechanisms that cause it to promote atherosclerosis, or clogging of the arteries.

Published in the January issue of the journal Arteriosclerosis, Thrombosis and Vascular Biology, the finding may give clues as to why some antioxidant therapies have not yielded more positive results.

New hope in fight against Huntington's disease

Hope for new ways of treating devastating neurodegenerative disorders such as Huntington's disease has been raised by a trans-Atlantic team of researchers thanks to the use of cutting-edge genetic techniques.

Monday, January 10, 2011 – Cleveland – Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers. The research has created a diagnostic scoring system that improves on established criteria.

Species loss tied to ecosystem collapse and recovery

PROVIDENCE, R.I. [Brown University] — The world's oceans are under siege. Conservation biologists regularly note the precipitous decline of key species, such as cod, bluefin tuna, swordfish and sharks. Lose enough of these top-line predators (among other species), and the fear is that the oceanic web of life may collapse.

Early investigations promising for detecting metastatic breast cancer cells

Research by engineers and cancer biologists at Virginia Tech indicate that using specific silicon microdevices might provide a new way to screen breast cancer cells' ability to metastasize.

HOUSTON - (Jan. 10, 2011) – All fat cells are not the same – a fact that has implications in the understanding and treatment of type 2 diabetes and obesity, said researchers from Baylor College of Medicine (www.bcm.edu) in a report that appears in the current issue of the Journal of Cell Biology (http://www.jcb.rupress.org/).