Body

Scientists have developed Australia's first adult induced pluripotent stem cell lines using skin biopsies from patients with the rare genetic disease Friedreich Ataxia (FA).

 U-M study shows

ANN ARBOR, Mich. – Surviving cancer may also mean surviving pain, according to a study by the University of Michigan Health System showing 20 percent of cancer survivors at least two years post diagnosis have current cancer-related chronic pain.

Doctors are calling for women to receive more information about the pitfalls of breast cancer screening, as well as the benefits, after some women who received false-positive results faced serious anxiety and reduced quality of life for at least a year.

A study published online by BJS, the British Journal of Surgery, shows that patients with false-positive results - where the mammogram is abnormal but no cancer is present - had to undergo more diagnostic procedures than women with breast cancer before they were given the all clear.

Chevy Chase, MD—According to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), exposure to electrical light between dusk and bedtime strongly suppresses melatonin levels and may impact physiologic processes regulated by melatonin signaling, such as sleepiness, thermoregulation, blood pressure and glucose homeostasis.

Chevy Chase, MD—A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), found higher Bisphenol A (BPA) levels in women with polycystic ovary syndrome (PCOS) compared to controls. Furthermore, researchers found a statistically significant positive association between male sex hormones and BPA in these women suggesting a potential role of BPA in ovarian dysfunction.

PHOENIX, Ariz. — Jan. 13, 2011 — Genomic research could help doctors better target a drug widely used to treat colorectal cancer patients, according to a study by Genomic Health Inc. (Nasdaq: GHDX) and the Translational Genomics Research Institute (TGen).

The drug, oxaliplatin, is widely used in colon cancer. It is used in early disease, following surgery in those cancers that are likely to recur. It is also used in advanced disease to slow progression of the cancer where it has spread to other parts of the body.

(PHILADELPHIA) –The discovery that high levels of high-density lipoprotein (HDL) cholesterol (the "good cholesterol") is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

WHAT:Adding new evidence to the debate on the best treatment for middle-ear infections, or acute otitis media, in young children, clinical researchers at the Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center have found antibiotics to be more effective than a placebo in relieving symptoms. These findings appear in the January 13th issue of the New England Journal of Medicine. The study was funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

The estimated total cost of cancer care in the United States in 2020 is expected to be $158 billion assuming the most recent observed patterns of incidence, survival, and cost remain the same. This represents a 27% increase from 2010 due only to the projected aging and growth of the US population, according to a study published online January 12th in The Journal of the National Cancer Institute.

Robot-assisted surgery dramatically improves outcomes in patients with uterine, endometrial, and cervical cancer, said researchers at the Jewish General Hospital's Lady Davis Institute for Medical Research in Montreal. Moreover, because of fewer post-operative complications and shorter hospital stays, robotic procedures also cost less.

These results were published in late 2010 in a series of studies in The Journal of Robotic Surgery and The International Journal of Gynecological Cancer.

Grand Rapids, Mich. (January 12, 2011) – Van Andel Research Institute (VARI) researchers have developed a method that can yield more information from archived newborn blood that has implications for a vast array of research, including population health studies and answering questions about diseases in infants and children.

23andMe presents top 10 most interesting genetic findings of 2010

MOUNTAIN VIEW, CA – January 11, 2011 – 23andMe has released its first annual list of what it felt to be the 10 most interesting and significant genetic findings in 2010, as part of an ongoing journey to understand the role of genetics in personal health and human development.

Scientists from Texas have made an important step toward understanding human mating behavior by showing that certain genes become activated in fruit flies when they interact with the opposite sex. This research, published in the January 2011 issue of the journal GENETICS (http://www.genetics.org), shows that courtship behaviors may be far more influenced by genetics than previously thought.

Caltech-led team creates damage-tolerant metallic glass

PASADENA, Calif.—Glass is inherently strong, but when it cracks or otherwise fails, it proves brittle, shattering almost immediately. Steel and other metal alloys tend to be tough—they resist shattering—but are also relatively weak; they permanently deform and fail easily.