Body

A European study investigating the links between diet and disease has found that people who consume more fruit and vegetables have a lower risk of dying from ischaemic heart disease – the most common form of heart disease and one of the leading causes of death in Europe. However, the authors point out that a higher fruit and vegetable intake occurs among people with other healthy eating habits and lifestyles, and that these factors could also be associated with the lower risk of dying from IHD.

A series of denials and a failure to formally investigate allegations of misconduct in Andrew Wakefield's MMR research meant the public was misled about the credibility of the paper for six years.

Dr Fiona Godlee, BMJ Editor in Chief, says the UK has consistently failed to take research misconduct seriously. She calls on the UK government to establish mandatory oversight of clinical research integrity within the NHS, as happens for publicly funded research in the USA.

Travel websites, especially those that offer 'last minute' deals, should inform people about the risks of malaria and the need to take preventative medication before travelling, say experts in infectious diseases today.

Their warning, in a letter to this week's BMJ, follows three recent cases of malaria in UK citizens returning from 'winter sun' holidays to the Gambia, where malaria is highly endemic.

While every cell of an organism contains the same genes only a proportion are expressed in any tissue at a given stage in development. Knowing the extent of gene transcription is valuable and a team of European researchers has generated an atlas of gene expression for the developing mouse embryo. This will be a powerful resource to determine co-expression of genes and to identify functional associations between genes relevant to development and disease. The findings will be published next week in the online, open access journal PLoS Biology.

  • Drinking in teens, especially binging, is a large problem within the Netherlands and European Union
  • A new study explored the relationship of drinking to remove or supress negative emotions (known as drinking to cope) with two different genes: DRD2 and SLC6A4
  • These results indicate that binge drinking and alcohol-related problems were strongly associated with drinking to cope and the presence of DRD2

There has been an abundance of research on the associations between drinking behavior and marital status, but many questions remain regarding the timing of when an individual gets married and divorced and if there is any relation to alcohol use. A new study released in the April 2011 issue of Alcoholism: Clinical & Experimental Research, which is currently available at Early View, explores that subject in detail and found that alcohol dependence was a strong predictor of both delays in marriage and early separation.

DALLAS, Jan. 18, 2011 – The American Heart Association has, for the first time, published a statement, "American Heart Association and Nonprofit Advocacy: Past, Present, and Future," that documents the association's longstanding commitment to improve heart and stroke-related public policy.

Women who were either in the transition to menopause or postmenopausal experienced a reduction in the frequency and severity of menopausal hot flashes with the use of the antidepressant medication escitalopram, compared to women who received placebo, according to a study in the January 19 issue of JAMA.

Atrazine is one of the most widely used herbicides in North American corn production, but heated controversy remains over the 50-plus-year-old product. Several other herbicides are used in corn production, and a host of non-chemical tactics are sometimes used, too. If the use of atrazine is restricted or banned altogether, how will sweet corn growers cope? A recent University of Illinois study shows sweet corn can be grown successfully without atrazine, but given today's approach, perhaps not very often.

COLUMBIA, Mo. – Frigid weather may seem like a good excuse to avoid workouts, stay inside and overindulge in comfort foods. However, health experts from the University of Missouri have found that these tendencies leave most people feeling less content during the winter months. MU researchers say people should establish new traditions to increase happiness and avoid wintertime woes.

We all want an apology when someone does us wrong. But a new study, published in Psychological Science, a journal of the Association for Psychological Science, finds that people aren't very good at predicting how much they'll value an apology.

Severe asthma in early childhood may lead to premature loss of lung function during adolescence and more serious disease during adulthood, researchers at Emory University School of Medicine report. Early identification and treatment of children with severe asthma is important to help stem asthma progression.

LA JOLLA, CA – January 18, 2011 – Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to test for biomedical potential. Already, one of the compounds has shown great promise in inhibiting replication of HIV particles and fighting inflammation.

UNC scientists who study how cells repair damage from environmental factors like sunlight and cigarette smoke have discovered how a "chaperone" enzyme plays a key role in cells' ability to tolerate the DNA damage that leads to cancer and other diseases.

The enzyme, known as Rad18, detects a protein called DNA polymerase eta (Pol eta) and accompanies it to the sites of sunlight-induced DNA damage, enabling accurate repair. When Pol eta is not present, alternative error-prone polymerases take its place – a process that leads to DNA mutations often found in cancer cells.

CHICAGO – January 18, 2011 – Maintaining periodontal health may contribute to a healthy respiratory system, according to research published in the Journal of Periodontology. A new study suggests that periodontal disease may increase the risk for respiratory infections, such as chronic obstructive pulmonary disease (COPD) and pneumonia. These infections, which are caused when bacteria from the upper throat are inhaled into the lower respiratory tract, can be severely debilitating and are one of the leading causes of death in the U.S.