Body

Intelligent microscopy

Micropilot detected these cells and then instructed the microscope to remove fluorescent tags from proteins in half of each cell’s nucleus, and record whether fluorescently-tagged proteins moved in from elsewhere.

(Photo Credit: EMBL)

Women who have become pregnant after egg donation should be categorized as high-risk patients. Why that is the case, and which consequences egg donation may have for women is the subject of a review article by Ulrich Pecks and co-authors from the University Hospital Aachen in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl In 2011; 108[3]: 23-31).

Chapel Hill, NC – A new study shows that a test of biomarkers for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma.

Despite the sophistication and range of contemporary microscopy techniques, many important biological phenomena still elude the precision of even the most sensitive tools. The need for refined imaging methods for fundamental research and biomedical applications related to the study of disease remains acute.

Protection against nerve gas attack is a significant component of the defense system of many countries around the world. Nerve gases are used by armies and terrorist organizations, and constitute a threat to both the military and civilian populations, but existing drug solutions against them have limited efficiency.

Most miscarriages in horses results at very early stages of pregnancy (within about three weeks) and it is generally believed that the primary cause is that the foetus grows or develops too slowly: smaller than normal embryos have a higher chance of being lost then normally sized ones. It is not clear whether low concentrations of progesterone lead to slower embryonic development but nevertheless the progestin altrenogest is routinely used to treat mares that frequently suffer miscarriages.

Climate change threatens many tree species, say Hebrew U. researchers

Jerusalem, January 23, 2011 -- Global warming is already affecting the earth in a variety of ways that demand our attention. Now, research carried out at the Hebrew University of Jerusalem indicates that many tree species might become extinct due to climate change if no action is taken in time.

Scientists at the University of East Anglia (UEA) have discovered a rogue gene which – if blocked by the right drugs – could stop cancer in its tracks.

Published today by the journal Oncogene, the discovery is a breakthrough in our understanding of how cancer spreads. It is hoped the research will lead to new drugs that halt the critical late stage of the disease when cancer cells spread to other parts of the body.

St. Louis, MO, January 24, 2011 – Asthma is one of the world's most common chronic diseases, affecting as many as 300 million people. It is estimated that by 2025 there could be an additional 100 million people with the disease. This rapid increase in asthma is most likely due to changing environmental or lifestyle factors, and over the last 15 years, changing diet has emerged as a promising contributor. Two studies published in the in the February 2011 issue of the Journal of the American Dietetic Association explore the possible relationship between nutrition and asthma.

A new study has found that tamoxifen, an anti-estrogen breast cancer medication, may reduce an individual's risk of death from lung cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study supports the hypothesis that there is a hormonal influence on lung cancer and that estrogen levels play a role in lung cancer patients' prognosis.

NEW YORK (24 January 2010)—A new study issued today by some of the world's top experts on forest governance finds fault with a spate of international accords, and helps explain their failure to stop rampant destruction of the world's most vulnerable forests. The report suggests that global efforts have too often ignored local needs, while failing to address the most fundamental challenge to global forest management—that deforestation usually is caused by economic pressures imposed from outside the forests.

It is known that teeth can protect themselves, to some extent, from attack by bacteria but that inflammation within a tooth can be damaging and, in extreme cases, lead to abscess or death of the tooth. New research published in BioMed Central's open access journal BMC Immunology shows that odontoblast cells are part of the immune system and fight to protect teeth from decay.

Stanford, CA— Plant biologists have discovered the last major element of the series of chemical signals that one class of plant hormones, called brassinosteroids, send from a protein on the surface of a plant cell to the cell's nucleus. Although many steps of the pathway were already known, new research from a team including Carnegie's Ying Sun and Zhiyong Wang fills in a missing gap about the mechanism through which brassinosteroids cause plant genes to be expressed.

DURHAM, N.C. – Despite what you might have heard, genetic sequencing alone is not enough to understand human disease. Researchers at Duke University Medical Center have shown that functional tests are absolutely necessary to understand the biological relevance of the results of sequencing studies as they relate to disease, using a suite of diseases known as the ciliopathies which can cause patients to have many different traits.