Body

Chemists turn gold to purple -- on purpose

Professor Richard Watt and his chemistry students suspected that a common protein could potentially react with sunlight and harvest its energy – similar to what chlorophyll does during photosynthesis.

The story of how they proved it sounds as colorful as the legend of the leprechaun who hid his pot of gold at the end of the rainbow.

Plymouth, Mich. – January 26, 2011 – Lycera Corporation, a biopharmaceutical company pioneering an innovative approach to developing novel oral medicines to treat autoimmune diseases, today announced positive data from the University of Michigan demonstrating the role of bioenergetics in selectively inhibiting pathogenic lymphocytes while preserving and enhancing the normal immune system. The findings, published online today in Science Translational Medicine, support Lycera's promising novel therapeutic approach to treating a broad spectrum of immune diseases.

Cancer researchers at Princess Margaret Hospital (PMH) have discovered that targeting an enzyme called Uroporphyrinogen Decarboxylase (UROD) can sensitize diseased tissue to radiation and chemotherapy, which could mean fewer side effects for individuals with head and neck cancer.

Researchers at the University of Illinois at Chicago College of Medicine have found that particular strains of a food-borne bacteria are able to invade the heart, leading to serious and difficult-to-treat heart infections.

The study is available online in the Journal of Medical Microbiology.

Orangutan DNA more diverse than human's, remarkably stable through the ages

One possible clue to the lack of structural rearrangement in orangutan DNA is a profound lack of repetitive "Alu" elements. These short stretches of DNA make up about 10 percent of the human genome and can pop up in unexpected places to create new mutations or genetic rearrangements.

HOUSTON -- (Jan. 27, 2011) – In the forests of Borneo and Sumatra, orangutans – the "men of the forest" in the language of Malaysia–swing among the trees, an endangered primate population so similar and yet different from man – and from each other, according to a recently published genome analysis of the two populations of orangutans still existing in the world.

The mechanism that controls the internal 24-hour clock of all forms of life from human cells to algae has been identified by scientists.

Not only does the research provide important insight into health-related problems linked to individuals with disrupted clocks – such as pilots and shift workers – it also indicates that the 24-hour circadian clock found in human cells is the same as that found in algae and dates back millions of years to early life on Earth.

The direct ancestors of orang-utans were once widely distributed in south-east Asia but the two modern orang-utan species are confined to the islands of Sumatra and Borneo. Both species are endangered, largely as a consequence of destruction of their rainforest habitat. The orang-utans are the only great apes that spend most of their time in trees. Nevertheless, the species share a number of features with other apes: they are adept in their use of tools and live in complex social groups that show evidence of cultural learning.

Northwestern University researchers have developed a new technique for rapidly prototyping nanoscale devices and structures that is so inexpensive the "print head" can be thrown away when done.

Hard-tip, soft-spring lithography (HSL) rolls into one method the best of scanning-probe lithography -- high resolution -- and the best of polymer pen lithography -- low cost and easy implementation.

January 26, 2011 – In a study published online today in Genome Research (www.genome.org), in coordination with the publication of the orangutan genome sequence, scientists have presented the surprising finding that although orangutans and humans are more distantly related, some regions of our genomes are more alike than those of our closest living relative, the chimpanzee.

Phosphate-free automatic dishwashing detergents — introduced to combat the phosphate-fed algae blooms that foul the nation's lakes and rivers — may be making the fish happy. But they're putting a frown on the faces of some consumers who say the new products leave dishes dirty. That's the topic of the cover story in the current edition of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine.

Scientists are reporting discovery of a potential biochemical basis for the apparent cancer-fighting ability of broccoli and its veggie cousins. They found for the first time that certain substances in the vegetables appear to target and block a defective gene associated with cancer. Their report, which could lead to new strategies for preventing and treating cancer, appears in ACS' Journal of Medicinal Chemistry.

Scientists are reporting successful application of the technology used in home devices to clean jewelry, dentures, and other items to make anticancer drugs like tamoxifen and paclitaxel dissolve more easily in body fluids, so they can better fight the disease. The process, described in ACS' journal, Langmuir, can make other poorly soluble materials more soluble, and has potential for improving the performance of dyes, paints, rust-proofing agents and other products.

For 60 years, scientists have puzzled over the possibility of a hepatic osmoreceptor that influences blood pressure regulation. Now, researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, the Experimental and Clinical Research Center (ECRC) of the MDC and Charité and the Hannover Medical School (MHH) appear to have made a breakthrough discovery. Dr. Stefan Lechner and Professor Gary R. Lewin (both of MDC), Professor Friedrich C.

Membrane molecule keeps nerve impulses hopping

CHAPEL HILL, N.C. -- New research from the University of North Carolina at Chapel Hill School of Medicine describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of nervous system impulses. The findings appear online Jan. 27, 2011 in the journal Neuron.