PORTLAND, Ore. — Researchers at Oregon Health & Science University Doernbecher Children's Hospital have defined the cell of origin for a kind of cancer called sarcoma. In a study published today as the Featured Article in the journal Cancer Cell, they report that childhood and adult sarcomas are linked in their biology, mutations and the cells from which these tumors first start. These findings may lead to non-chemotherapy medicines that can inhibit "molecular targets" such as growth factor receptors, thereby stopping or eradicating the disease.
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Millions of Americans, or 10 percent of the population, suffers from daily heartburn or other symptoms of reflux such as regurgitation, chronic cough, hoarseness and dental erosions. Until recently, many of these patients faced either a lifetime of daily medications, incomplete resolution, or worsening of their symptoms while treatment options were often limited to surgery. Scott & White Healthcare – Round Rock is offering a new procedure to patients who meet specific requirements and are generally not doing well on daily medications known as Proton Pump Inhibitors (PPIs).
Practical medical advice that works in the "real world" may more effectively prevent cardiovascular disease in women than recommendations based only on findings in clinical research settings, according to the 2011 update to the American Heart Association's cardiovascular disease prevention guidelines for women.
First published in 1999, the guidelines until now have been primarily based on findings observed in clinical research. That alone often doesn't consider the personal and socioeconomic factors that can keep women from following medical advice and treatment.
According to Dr Annette Baudisch of the Max Planck Institute for Demographic Research in Rostock, Germany, current methods of comparing patterns of ageing are limited because they confound two different elements of ageing – pace and shape.
Obesity is a killer in its own right, irrespective of other biological or social risk factors traditionally associated with coronary heart disease, suggests research published online in Heart.
Increasing weight is associated with a higher prevalence of known risk factors for coronary artery disease, such as diabetes, high blood pressure and cholesterol. And it has been assumed that these have been responsible for the increased risk of heart disease seen in obesity, say the authors.
Portable pedal machines could help counter the harmful effects of prolonged periods spent at a desk or workstation among an increasingly sedentary workforce, suggests a small study published online in the British Journal of Sports Medicine.
The researchers base their findings on 18 full time employees who were given a pedal exercise machine for four weeks, specifically designed to be used while seated at a desk in the workplace.
Healthcare practitioners can increase the number of patients with heart disease referred to a cardiac rehabilitation program by 40 per cent, helping them to reduce their risk of dying and improve their quality of life, say researchers at the Peter Munk Cardiac Centre.
That human evolution follows a progressive trajectory is one of the most deeply-entrenched assumptions about our species. This assumption is often expressed in popular media by showing cavemen speaking in grunts and monosyllables (the GEICO Cavemen being a notable exception). But is this assumption correct? Were the earliest humans significantly different from us?
In a paper published in the latest issue of Current Anthropology, archaeologist John Shea (Stony Brook University) shows they were not.
Most medical devices recently recalled by the Food and Drug Administration because of very serious risks were initially approved through an expedited process or were exempt from regulatory review, according to a report posted online today that will be published in the June 14 print issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Dietary fiber may be associated with a reduced risk of death from cardiovascular, infectious and respiratory diseases, as well as a reduced risk of death from any cause over a nine-year period, according to a report posted online today that will be published in the June 14 print issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Cigarette smoking may be associated with an increased risk of developing the muscle-wasting disease amyotrophic lateral sclerosis (ALS), according to a report in the February issue of Archives of Neurology, one of the JAMA/Archives journals.
Individuals who have higher blood glucose levels and poorer control of those levels over time appear more likely to develop eye-related complications 10 years later, according to a report in the February issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
Obesity may be associated with higher eye pressure and a decreased risk of open-angle glaucoma in women but not men, according to a report posted online today that will appear in the May issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
MADISON — With one arm raised and a determined scowl, the figure looks ready to march right off his carved tablet and into the history books. If only we knew who he was - corn god? Tribal chief? Sacred priest?
"It's beautiful and was obviously very important," says University of Wisconsin-Madison archaeologist John Hodgson of the newly discovered stone monument. "But we will probably never know who he was or what the sculpture means in its entirety."
Women prefer female service providers in situations where they might fall prey to stereotypes about their math and science abilities, according to a new study in the Journal of Consumer Research.
"One of the most widely held stereotypes in North America is that women's competence and aptitude in science, technology, engineering, and math (STEM) domains is less than men's," write authors Kyoungmi Lee (Yonsei University, Korea), Hakkyun Kim (Concordia University, Canada), and Kathleen Vohs (University of Minnesota).