Body

A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses.

"There are no effective cures for mitochondrial diseases, even in animals," said study leader Marni J. Falk, M.D., who cares for children in the Mitochondrial-Genetics Disease Clinic at The Children's Hospital of Philadelphia. "So these striking results in mice may suggest a novel therapy of direct relevance for humans."

ATLANTA – May 19, 2011 – A new report from the American Cancer Society details cancer control efforts and outlines improvements as well as gaps in preventive behavior that contribute to cancer mortality. Increasing rates of obesity observed since the early 1980s appear to have slowed in the past decade, particularly among women and girls, but nearly one in five adolescents and about one in three adults is obese. Vaccination against the virus that causes cervical cancer is up, but smoking declines have stalled.

Men who have been diagnosed with poor sperm quality and who are trying to have children should limit their cell phone use. Researchers have found that while cell phone use appears to increase the level of testosterone circulating in the body, it may also lead to low sperm quality and a decrease in fertility.

GENEVA, 19 May 2011: Today 16 countries announced new commitments to dramatically reduce maternal, newborn and child mortality, as part of the Global Strategy for Women's and Children's Health.

PROVIDENCE, R.I. [Brown University] — Dozens of studies on whether moderate exercise can curb the nicotine cravings of women smokers have added up to an apparent contradiction: it seems to work in short-term, well controlled lab experiments, but then fizzles out in treatment trials. A new study may explain why and help researchers devise a practical therapy.

After corn is processed to make ethanol, what's left of the corn looks something like slightly dampened cornmeal, though a somewhat darker yellow, and not as finely ground. Known as "wet distiller's grains with solubles" (WDGS), this byproduct is sometimes used as a cattle feed ingredient. U.S. Department of Agriculture (USDA) scientists in Clay Center, Neb., are studying the pros and cons of that practice.

A G8 report released today in Paris indicating an increase in financing for women's and children's health was welcomed by the Partnership for Maternal, Newborn and Child Health (PMNCH).

In 2010, the G8 launched the Muskoka Initiative for Maternal, Newborn and Child Health, with an initial commitment of US$5 billion by 2015. The G8 2011 Accountability Report today suggests that collectively the G8 will surpass this initial commitment by roughly 53%.

Chronic lower back pain is a major problem for society – behind only headaches as the most common neurological ailment – and is frequently caused by degeneration of the intervertebral disc.

Researchers have worked for many years to find a way of repairing the wear and tear on the lower back.

Now, in results published in the journal Soft Matter, they have discovered how to permanently replace the workings of the invertebral disc.

Jaws made of bone are commonplace in the animal kingdom. However, how jaws developed in the course of evolution is still a mystery. Under the direction of paleontologist Nicolas Goudemand, a team of researchers from the University of Zurich and the European Synchrotron Radiation Facility set about solving this puzzle. Living and extinct jawless animals can yield clues as to the development of the jaw. The researchers studied fossilized conodonts – extinct, eel-shaped animals whose precise relationship with the actual vertebrates is still a matter of debate.

RTOG reports on the largest trial to-date for patients with newly diagnosed glioblastoma demonstrating the importance and feasibility of prospective molecular analysis of tumor tissue although finding that patients received no additional benefit from dose-intensive temozolomide as compared to standard adjuvant temozolomide after combined temozolomide and radiotherapy.

Alexandria, Va. – The American Society of Clinical Oncology (ASCO) today highlighted several studies in a press briefing from among more than 4,000 abstracts publicly posted online at www.asco.org in advance of ASCO's 47th Annual Meeting. An additional 17 plenary, late-breaking and other major studies will be released in on-site press conferences at the Annual Meeting.

DALLAS – May 19, 2011 – Ray Johnston's goal in three years is for his band to sell out at the 1,600-seat House of Blues in Dallas. In eight years, he wants to pack the 6,400-seat Verizon Theatre in Grand Prairie, and by 2030, to play to tens of thousands of fans at Cowboys Stadium in Arlington.

Mr. Johnston's unmentioned goal, though, is to live another year after battling leukemia for the past seven. Despite four relapses, the former Dallas Mavericks basketball player is enjoying life as a rising musician in The Ray Johnston Band.

Analysis of a 440-year-old document reveals new details about native population decline in the heartland of the Inca Empire following Spanish conquest in the 16th century.

Archaeologists have discovered a 12,000-year-old iron oxide mine in Chile that marks the oldest evidence of organized mining ever found in the Americas, according to a report in the June issue of Current Anthropology.

A team of researchers led by Diego Salazar of the Universidad de Chile found the 40-meter trench near the coastal town of Taltal in northern Chile. It was dug by the Huentelauquen people—the first settlers in the region—who used iron oxide as pigment for painted stone and bone instruments, and probably also for clothing and body paint, the researchers say.

Researchers at the University of Oxford have developed a cheap and reliable diagnostic test for a rare form of cancer. The test involves screening tumour samples for a particular molecular fingerprint unique to this type of cancer.