PORTLAND, Ore. - Oregon Health & Science University Knight Cancer Institute researchers uncovered a gene that may be the key to helping kidney cancer patients who don't respond to current therapies. This discovery could also provide a toolkit to identify patients who are most likely to benefit from drugs that block this gene from causing cancer cells to grow.
Body
The researchers created the 3-D model using the parameters of the Mount St. Helens blast including equations to determine mass, momentum and the heat energy of the gas, along with the size, density, specific heat and thermal conductivity of the solid particles.
"We integrated a wide range of geophysical and geochemical data to develop rigorous initial and boundary conditions for hydrodynamics calculations that reproduced, to an amazing degree, the observed dynamics of the blast envelope," said Voight.
MAYWOOD, Ill. -- Baseline concussion tests given to hundreds of thousands of athletes might, paradoxically, increase risks in some cases, according to a Loyola University Health System researcher.
The tests likely have a high "false negative" rate, meaning a test shows an athlete has recovered, when in fact he or she is still experiencing cognitive impairments from the concussion.
CHICAGO, IL (June 5, 2011)––Each year, kidney cancer is diagnosed in nearly 60,000 people in the U.S. Many of these patients undergo surgery to remove the affected kidney, but this procedure can be risky for the elderly and those who have other health problems. Unfortunately, the prognosis of kidney cancer patients often cannot be determined until tumor samples are surgically removed and evaluated.
WASHINGTON (June 1, 2011) – By using mice lacking a crucial gene that controls the process of chromatin remodeling of cytokines including those responsible for inflammation and comparing them to normal wild type mice with the gene, researchers at the George Washington University School of Medicine and Health Sciences have shown that the gene, Mta1, is essential for the parasite Schistosoma haematobium to establish a productive infection and survival in the host.
Scientists have uncovered the structure of the protein complex that assembles the tiny hair-like strands that cover the outside of bacteria. Called pili, these 'hairs' allow bacteria to group together and stick to human cells to cause infection - and are therefore a key target for a new generation of antibiotics.
UPTON, NY - New atomic-level "snapshots" published in the June 2, 2011, issue of Nature reveal details of how bacteria such as E. coli produce and secrete sticky appendages called pili, which help the microbes attach to and infect human cells. "These crystal structures unravel a complex choreography of protein-protein interactions that will aid in the design of new antibacterial drugs," said Huilin Li, a biophysicist at the U.S.
JUNE 1, 2011 – The American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Healthcare Epidemiology of America (SHEA) have updated their 2003 joint guideline for reprocessing gastrointestinal endoscopes to reaffirm reprocessing methods and take into account evolved technology and disinfection systems.
COLUMBIA, Mo. – Binge drinking among college students has long been viewed as dangerous and destructive. Government and non-profit health organizations spend millions of dollars annually on public service announcements (PSAs) aimed at dissuading college students from hazardous drinking habits. These organizations primarily use "loss-framed", or negative messages to show the dangers of binge drinking.
Cisplatin is one of the most widely used anticancer chemotherapeutics. However, it has some severe side effects in normal tissues, in particular it is toxic to the kidneys. Understanding the mechanisms underlying this toxicity could identify targets for drugs that could be given together with cisplatin to protect the kidney during chemotherapy. In this context, a team of researchers, led by Zheng Dong, at Georgia Health Sciences University, Augusta, has now identified the signaling protein PKC-delta as a critical regulator of cisplatin-mediated kidney toxicity in mice.
BOSTON—Scientists at Dana-Farber Cancer Institute have identified an overactive network of growth-spurring genes that drive stem-like breast cancer cells enriched in triple-negative breast tumors, a typically aggressive cancer that is highly resistant to current therapies.
COLUMBIA, Mo. ¬— Previous studies have shown that customer satisfaction plays a key role in the health and future success of any company. When customers are satisfied, they keep coming back to the same store and invite their friends to do the same. Now, a new study from the University of Missouri has found that CEOs who pay attention to employees' job satisfaction are able to boost both customer satisfaction and "repurchase intentions," or the number of customers that intend to purchase products from the store.
That's what viewers of the past HBO series Sex and the City may ask themselves when faced with the prospect of uncomfortable discussions about sexual health with partners, friends and doctors.
Researchers found that college students were more than twice as likely to talk about sexual health issues with their partners after watching a Sex and the City episode featuring the characters Samantha and Miranda having similar conversations, compared to students who saw different episodes.
CHICAGO --- Gay young men in serious relationships are six times more likely to have unprotected sex than those who hook up with casual partners, according to new Northwestern Medicine research.
The findings provide a new direction for prevention efforts in this population who account for nearly 70 percent of all new HIV/AIDS diagnoses in adolescents and young adults in the United States and who also have the highest increase in new infections.
MADISON — It's an issue that crops up wherever humans and big predators — wolves, bears, lions — coexist.
"It's just hard to live alongside large carnivores. They damage crops, they kill livestock and pets, they threaten people's safety," says University of Wisconsin-Madison professor Adrian Treves. And the sheer presence of a wolf nearby has typically been enough to make farmers fear for their animals, he adds. "Wherever there were carnivores, people thought there was risk."