PORTLAND, Ore. — Eating a high-fat diet during pregnancy increases the chance of stillbirth, according to new research at Oregon Health & Science University. The new data show eating a typical American diet, which is high in fat, decreases blood flow from the mother to the placenta, the temporary organ that nourishes the unborn fetus. Prior to this study, exactly how a fatty diet contributes to stillbirth was unclear. The findings are published in the June edition of the journal Endocrinology.
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Baltimore, MD -- A multicenter clinical trial led by a researcher at the University of Maryland Marlene and Stewart Greenebaum Cancer Center will evaluate a new approach to treat triple-negative breast cancer, an often-aggressive type of cancer that is more common among African-Americans and young women. The study will help researchers determine if an experimental drug, entinostat, can reprogram tumor cells to express a protein called an estrogen receptor to make them sensitive to hormone therapy.
Two promising new treatments to aid people with autism have shown effectiveness in pilot studies conducted by an Arizona State University professor and private researchers.
Several studies indicate that children with autism often have abnormalities in critical biochemical functions that help maintain health – specifically methylation, glutathione, and mitochondrial functions.
Methylation turns proteins in the body on and off – including DNA and RNA – a function that controls gene activity.
Managers of northern Michigan forests may not see the birds for the trees – or at least are in danger of losing sight of songbird neighborhoods when looking out for timber harvests.
LOUISVILLE, Ky. – University of Louisville researchers are one step closer to helping millions of people whose salivary glands no longer work because of disease or damage from treatment of diseases.
The scientific finding of Douglas Darling, PhD, professor, Department of Oral Health and Rehabilitation, UofL School of Dentistry, and his team identified a protein sorting mechanism used by the salivary gland. The National Institutes of Health supported study published on-line first this week in the Journal of Dental Research.
Scientists from the Florida campus of The Scripps Research Institute have uncovered a potentially important new therapeutic target that could prevent stress-related cell death, a characteristic of neurodegenerative diseases such as Parkinson's, as well as heart attack and stroke.
In the study, published recently in the journal ACS Chemical Biology, the scientists showed they could disrupt a specific interaction of a critical enzyme that would prevent cell death without harming other important enzyme functions.
The nation's system of freeing some terminally ill prisoners on grounds of compassionate release is so riddled with medical flaws and procedural barriers that many potentially medically eligible inmates are dying behind bars, say UCSF researchers in a new study.
The research, which calls for an overhaul of current practices, is published online this week in Annals of Internal Medicine.
CORVALLIS, Ore. – One of the beneficial compounds found in green tea has a powerful ability to increase the number of "regulatory T cells" that play a key role in immune function and suppression of autoimmune disease, according to new research in the Linus Pauling Institute at Oregon State University.
This may be one of the underlying mechanisms for the health benefits of green tea, which has attracted wide interest for its ability to help control inflammation, improve immune function and prevent cancer.
(SALT LAKE CITY)—Parents and health care providers can't always tell whether toddlers display signs of autism syndrome disorder (ASD), but new research from the University of Utah shows that a significant portion of at-risk children between 14-24 months can be identified through systematic screening by autism experts and providers working together.
As the World Health Organisation suggests the E. coli outbreak in Germany is a strain never before seen in an outbreak – O104:H4 – laboratory science conducted at the University of Southampton indicates a role for copper in preventing the spread of such infections.
Medical researchers may have uncovered a novel approach to treat an incurable and ultimately fatal neurodegenerative disease that affects hundreds of thousands of people.
Two international studies, one led by the University of Leicester, and the other a collaboration with Leicester led by scientists in the USA, hold out promise for slowing down the development of Huntington's disease – and potentially, Alzheimer's and Parkinson's diseases. The research, which is in its early stages, represents an important milestone in understanding these debilitating conditions.
New research identifies genetic mutations that cause an inherited form of cataracts in humans. The study, published online June 2 by Cell Press in the American Journal of Genetics, provides new insight into the understanding of lens transparency and the development of cataracts in humans.
Researchers at King's College London have identified a way of eliminating leukaemic stem cells, which could lead to new treatments that may enable complete remission for leukaemia patients. An early study in mice has shown that leukaemic stem cells can be abolished by suppressing two proteins found in the body.
Mutations of DNA that lead to one base being replaced by another don't have to happen as single, independent events in humans and other eukaryotes, a group of Indiana University Bloomington biologists has learned after surveying several creatures' genomes.
And, the scientists argue, if "point mutations" can happen in twos, threes -- even nines – large evolutionary jumps are possible, especially when problems caused by a single point mutation are immediately compensated for by a second or third. The work appears in the latest issue of Current Biology.
PHILADELPHIA (June 2, 2011) -- Although bitterness can sometimes be desirable – such as in the taste of coffee or chocolate – more often bitter taste causes rejection that can interfere with food selection, nutrition and therapeutic compliance. This is especially true for children. Now, scientists from the Monell Center and Integral Molecular describe the discovery of a compound that inhibits bitterness by acting directly on a subset of bitter taste receptors.