SEATTLE – Researchers at Fred Hutchinson Cancer Research Center have demonstrated in mice that the performance of a novel biomarker-development pipeline using targeted mass spectrometry is robust enough to support the use of an analogous approach in humans. The findings, by principal investigator Amanda Paulovich, M.D., Ph.D., an associate member of the Hutchinson Center's Clinical Research Division, are published in Nature Biotechnology.
Body
Boston, MA (June 19, 2011)—Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria of most organisms eagerly absorb this chemical compound. Because calcium levels link to many essential biological processes, not to mention conditions such as neurological disease and diabetes, scientists have been working for half a century to identify the molecular pathway that enables these processes.
Heavy and prolonged snowfall can bring about unexpected conditions that encourage fungal growth, leading to the death of plants in the Arctic, according to experts.
A new international study confirms that whilst snow has an insulating effect which helps plants to grow bigger, heavy and prolonged snow can, in certain circumstances, also encourage the rapid and extensive growth of killer fungal strains.
A compound that for about 60 years has been used as a drug against tapeworm infection is also apparently effective against colon cancer metastasis, as studies using mice have now shown. The compound silences a gene that triggers the formation of metastases in colon cancer. Professor Ulrike Stein (Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, (MDC)) and her research group made this discovery in collaboration with Professor Robert H.
The U.S. Medicaid program is likely paying far more than necessary for medications and not offering patients the most effective ones available, by ignoring international evidence-based lists of safe and effective medications, according to a new study by researchers at University of California, San Francisco.
It pays to prevent fractures. That's one of the main findings of a landmark report 'Osteoporosis – Burden, Healthcare provision and Opportunities in the European Union' newly published in the journal Archives of Osteoporosis. The study, compiled by the International Osteoporosis Foundation (IOF) in collaboration with the European Federation of the Pharmaceutical Industries and Associations (EFPIA), calculates the future burden of fractures as a consequence of increasing treatment uptake in the five largest European countries as well as Sweden.
A University of Exeter biologist has discovered a 'lost' species of bat breeding on the Isles of Scilly (UK). A pregnant female brown long-eared bat is the first of its species to be found on the islands for at least 40 years. It was discovered by Dr Fiona Mathews, Senior Lecturer at the University of Exeter, a postgraduate student and a team from the Wiltshire Bat Group.
Negative-pressure wound therapy probably does not promote healing. This is the conclusion of Frank Peinemann and Stefan Sauerland's meta-analysis in the current edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2011; 108[22]: 381-9).
In a new study revealing key steps for controlling plant growth, Australian researchers have shown how the assembly of components of the plant cell wall regulates growth of root hairs. Root hairs are important structures that allow plants to absorb essential nutrients and water from the soil. The research will assist in contributing to the sustainability of Australia's plant -based industries such as, agriculture, horticulture and forestry.
The way you relate to your partner can affect your long-term mental and physical health, study shows
The potentially lasting implications of day-to-day couple conflict on physical and mental well-being are revealed in a study published today in the journal Personal Relationships.
Researchers at the Keck School of Medicine of the University of Southern California (USC) have uncovered structural clues about the protein linked to Parkinson's disease (PD), which ultimately could lead to finding a cure for the degenerative neurological disorder.
The alpha-synuclein (α-synuclein) protein is commonly found in the healthy human brain even though its function is not clear. The protein has been the subject of substantial Parkinson's research, however, because it is a major component in the protein clumps found in PD cases.
We know that poor social and physical environments can harm young children's cognitive and behavioral development, and that development often improves in better environments. Now a new study of children living in institutions has found that intervening early can help young children develop language, with those placed in better care by 15 months showing language skills similar to children raised by their biological parents.
ATLANTA – June 17, 2011 – A steady reduction in overall cancer death rates translates to the avoidance of about 898,000 deaths from cancer between 1990 and 2007, according to the latest statistics from the American Cancer Society. However, the report, Cancer Statistics 2011, and its companion consumer publication Cancer Facts & Figures 2011 find that progress has not benefitted all segments of the population equally.
A large, national multi-center study of thousands of children taken to emergency departments with minor blunt head trauma has found that most of those with normal computed tomography (CT) scans do not require hospitalization for further observation.
Of the more than 13,500 children included in the study, less than 1 percent had subsequent abnormal CT scans or MRIs and none required neurosurgical intervention.