If the obvious reasons for avoiding recreational drug use aren't off-putting enough, physicians have yet another detrimental consequence to add to the list – crusty, purplish areas of dead skin that are extremely painful and can open the door to nasty infections.
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RICHLAND, Wash. – A new computer model of blue-green algae can predict which of the organism's genes are central to capturing energy from sunlight and other critical processes.
"The consensus was that no one would ever measure dinosaur body temperatures, that it's impossible to do," says John Eiler, a coauthor and the Robert P. Sharp Professor of Geology and professor of geochemistry. And yet, using a technique pioneered in Eiler's lab, the team did just that.
HOUSTON -- (June 23, 2011) – The ability to identify self and non-self enables cells in more sophisticated animals to ward off invading infections, but it is critical to even simpler organisms such as the social amoebae Dictyostelium discoideum.
WASHINGTON — Limiting television and other media use, encouraging infants and young children in preschool and child care to spend more time in physically active play, and requiring child care providers to promote healthy sleeping practices are some of the actions needed to curb high rates of obesity among America's youngest children, says a new report from the Institute of Medicine.
Ian Jonsen, a research associate and adjunct professor in the Department of Biology at Dalhousie University and co-lead investigator of the Future of Marine Animal Populations Project (FMAP), has teamed up with Barbara Block at Stanford University and several other American researchers to conclude a two year study entitled, "Tracking apex marine predator movements in a dynamic ocean" published in the science journal Nature released June 22.
NEW YORK (June 23, 2011)—Fish communities in the 21st Century live fast and die young. That's the main finding of a recent study by researchers from the Wildlife Conservation Society who compared fish recently caught in coastal Kenya with the bones of fish contained in ancient Swahili refuse heaps in order to understand how to rebuild the current fisheries.
SALT LAKE CITY, Utah and EMERYVILLE, Calif. – PRESS RELEASE EMBARGOED UNTIL 12:00 P.M. EASTERN, June 23, 2011 – Scientists from the University of Utah and Omicia, Inc., a privately held company developing tools to interpret personal genome sequences, today announced the publication in Genome Research of a new software tool called VAAST, the Variant Annotation, Analysis and Selection Tool, a probabilistic disease-causing mutation finder for individual human genomes.
Massachusetts General Hospital investigators appear to have found the mechanism behind a previously reported link between the rare genetic condition Gaucher disease and the common neurodegenerative disorder Parkinson's disease. In a report to appear in the July 8 issue of Cell and receiving early online release, they describe how disruption of the molecular pathway that causes Gaucher disease leads to the toxic neuronal deposits of the protein alpha-synuclein (α-syn) found in Parkinson's and related disorders.
Harnessing the new generation of rapid, highly accurate gene-sequencing techniques, a research team has identified the disease-causing mutation in a newly characterized rare genetic disease, by analyzing DNA from just a few individuals. The power and speed of the innovative bioinformatics tool marks a step toward personalized genomics—discovering causative mutations in individual patients.
Many people when stressed turn to high calorie "comfort foods". Despite the contribution this behavior makes to the current obesity epidemic, little is known about the molecules and nervous system circuits that control it. Insight into this could provide new targets for the development of therapeutics to curb this potentially detrimental behavior.
None of us are strangers to stress of various kinds. It turns out the effects of all those stresses can change the fate of future generation, influencing our very DNA without any change to the underlying sequence of As, Gs, Ts and Cs. Now, researchers reporting in the June 24th issue of Cell, a Cell Press publication, have new evidence that helps to explain just how these epigenetic changes really happen.
The ultimate source of some cancers is embryonic cells. Research published in the June 24th Cell, a Cell Press publication, traces the precursor of deadly esophageal cancers to leftover embryonic cells found in all adults.
Some people with gastric reflux disease have a greater risk of developing esophageal cancer. These patients often have Barrett's esophagus, a condition in which intestinal-like cells appear in the esophagus. Esophageal cancers are difficult to treat and, together with gastric adenocarcinomas, kill more than a million people each year.
Researchers at RIKEN have uncovered a mechanism by which the effects of stress in the fly species Drosophila are inherited epigenetically over many generations through changes to the structure of chromatin, the material that makes up the cell nucleus. Published in the journal Cell, the results highlight the role of the transcription factor dATF-2 in chromatin assembly, marking a major advance in our understanding of non-Mendelian inheritance.
Double-stranded (ds) RNA viruses are a diverse group of viruses that include rotaviruses, a common cause of gastroenteritis. The ability of the immune system to detect and destroy viruses is critical for human health and survival. Now, a study published by Cell Press in the June 23rd issue of the journal Immunity identifies a novel sensor that is necessary to activate the immune response to viral infection. The research enhances our understanding of the complex and overlapping mechanisms our immune cells use to thwart infection.