The process of cell division is tightly regulated, as mistakes may lead to cancer. The so-called c-JUN protein has been fingered as causing tumors in both skin and liver. The group of Veronika Sexl at the University of Veterinary Medicine, Vienna, has now uncovered a surprising detail with the discovery an additional function of c-JUN's also prevents silencing of an important anti-tumor factor. The results have recently been published in the open-access journal Oncotarget.
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Baltimore, Maryland, June 28, 2011 – Nurses on a surgical intensive care unit (SICU) at a large academic medical center cut bloodstream infections to zero and saved more than $200,000 during a six-month period.
Baltimore, Maryland, June 28, 2011 – Nurses, occupational and physical therapists, case managers and education staff, all working together at a 300-bed Nebraska rehabilitation hospital, have successfully implemented a team approach to dramatically reduce infections from urinary catheters, the most prevalent type of infection acquired in healthcare settings.
OAK BROOK, Ill. – Breast cancer screening with mammography results in a significant reduction in breast cancer mortality, according to long-term follow-up results of a large-scale Swedish trial. The results are published online in the journal Radiology.
"Mammographic screening confers a substantial relative and absolute reduction in breast cancer mortality risk in the long-term," said Stephen W. Duffy, M.Sc., professor of cancer screening at Queen Mary, University of London. "For every 1,000 to 1,500 mammograms, one breast cancer death is prevented."
Results from the longest running breast screening trial show that screening with mammography reduces the number of deaths from breast cancer.
The study*, by researchers at Queen Mary, University of London, shows that the number of deaths that are prevented goes up year after year.
The results are new evidence of the long-term benefits of regular breast screening.
Senior author, Professor Stephen Duffy explained: "Breast cancer can take many years to develop so to tell if screening is effective, we need to see how women fair in the long-term.
DALLAS – June 28, 2011 – UT Southwestern Medical Center maternal-fetal specialists have confirmed a potential new protocol to protect pregnant women who are at risk for hepatitis B, a health problem that affects 2 billion people worldwide.
An accelerated hepatitis B vaccination schedule for high-risk pregnant women was found effective and well-tolerated. The findings appear in the journal Obstetrics & Gynecology.
PULLMAN, Wash.—A Washington State University student seeks to challenge a widely held assumption on the best way to analyze old DNA in anthropological and forensic investigations.
Sarah "Misa" Runnells makes her claim in the pay-to-publish journal PLoS ONE. At issue is the best way to sequence "ancient" DNA, bits of genetic code pulled from remains up to 800,000 years old. Such remains tend to be chemically degraded, making it difficult to draw accurate connections between, say a wooly mammoth and modern animals, or Neanderthals and humans.
LA JOLLA, CA-A recent study from scientists at the Salk Institute for Biological Studies suggests that a strawberry a day (or more accurately, 37 of them) could keep not just one doctor away, but an entire fleet of them, including the neurologist, the endocrinologist, and maybe even the oncologist.
Vanderbilt-Ingram Cancer Center researchers have identified six subtypes of an aggressive and difficult-to-treat form of breast cancer, called "triple-negative breast cancer (TNBC)."
SAN ANTONIO (June 27, 2011) — In the constant battle to lose inches or at least stay the same, we reach for the diet soda. Two studies presented June 25 and 27 at the American Diabetes Association's Scientific Sessions in San Diego suggest this might be self-defeating behavior.
A review of documentation relating to a clinical trial of the epilepsy drug gabapentin suggests that the study may have been a "seeding trial" used to promote the drug and increase prescribing, according to a report in the June 27 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
STANFORD, Calif. — A combination of calcium and vitamin D may cut the chance of melanoma in half for some women at high risk of developing this life-threatening skin cancer, according to a new study by Stanford University School of Medicine researchers.
Stress management programs like Transcendental Meditation should be implemented to significantly reduce depression, heart attacks, strokes and deaths in coronary heart disease patients, according to a new editorial written by a Cedars-Sinai Heart Institute physician, C. Noel Bairey Merz, MD, and published in Archives of Internal Medicine.
A team of Yale Cancer Center researchers has confirmed that between 10-20% of breast cancers classified as Estrogen Receptor (ER) negative are really positive. Understanding when and why breast cancers may be misclassified has important implications for treatment and outcomes for women diagnosed with breast cancer. Its findings are published online in the June 28 Journal of Clinical Oncology.
Yale School of Medicine researchers have found that a clinical trial of the epilepsy drug gabapentin may have been a "seeding trial" used by a pharmaceutical company to promote the drug and increase prescriptions, according to a report in the June issue of Archives of Internal Medicine, one of the JAMA/Archives journals.