Body

Massachusetts General Hospital (MGH) researchers have discovered the first of an entirely new class of antiangiogenesis drugs – agents that interfere with the development of blood vessels. In a report in Proceedings of the National Academy of Sciences/Early Edition, the investigators describe how a compound derived from a South American tree was able, through a novel mechanism, to interfere with blood vessel formation in animal models of normal development, wound healing and tumor growth.

Woods Hole Oceanographic Institution (WHOI) researchers have filled an important gap in the study of tunicate evolution by genetically sequencing 40 new specimens of thaliaceans, gelatinous, free-swimming types of tunicates. Their study was featured on the cover of the June issue of the Journal of Plankton Research.

Tunicates are a phylum of animals closely related to vertebrates, with a firm, rubbery outer covering called a tunic, from which the name derives.

GAINESVILLE, Fla. --- A new study co-authored by University of Florida researchers provides details on the first cookiecutter shark attack on a live human, a concern as warm summer waters attract more people to the ocean.

The study currently online and appearing in the July print edition of Pacific Science warns that swimmers entering the cookiecutter's range of open ocean tropical waters may be considered prey.

Under certain conditions, private and commercial propeller planes and jet aircraft may induce odd-shaped holes or canals into clouds as they fly through them. These holes and canals have long fascinated the public and now new research shows they may affect precipitation in and around airports with frequent cloud cover in the wintertime.

Studies by U.S. Department of Agriculture (USDA) scientists have confirmed that the presence of Escherichia coli pathogens in surface waters could result from the pathogen's ability to survive for months in underwater sediments. Most E. coli strains don't cause illness, but they are indicator organisms used by water quality managers to estimate fecal contamination.

These findings, which can help pinpoint potential sources of water contamination, support the USDA priorities of promoting sustainable agriculture and food safety.

Professor Bill Keevil, Head of the Microbiology Group and Director of the Environmental Healthcare Unit at the University of Southampton, has presented research into the mechanism by which copper exerts its antimicrobial effect on antibiotic-resistant organisms at the World Health Organization's first International Conference on Prevention and Infection Control (ICPIC).

If a person were to climb a towering redwood and take a sample from the top and bottom of the tree, a comparison would show that the DNA are different.

Christopher A. Cullis, chair of biology at Case Western Reserve University, explains that this is the basis of his controversial research findings.

Cullis, who has spent over 40 years studying mutations within plants, most recently flax (Linum usitatissimum), has found that the environment not only weeds out harmful and useless mutations through natural selection, but actually influences helpful mutations.

As our bodies first form, developing cells are a lot like children put on the school bus with their names and addresses pinned to their shirts.

The notes identify one as a future heart cell, another as a liver cell, a third as a neuron. And that's what they each grow up to be.

But once those cells reach adulthood, changes to those original marching orders caused by aging, disease and other stressors like smoking can precipitate a kind of identity crisis, researchers at the University of Michigan Health System have found.

The world's largest database on plants' functional properties, or traits, has been pub-lished. Scientists compiled three million traits for 69,000 out of the world's ~300,000 plant species. The achievement rests on a worldwide collaboration of scientists from 106 re-search institutions. The initiative, known as TRY, is hosted at the Max Planck Institute for Biogeochemistry in Jena (Germany).

Geoffroy Berthelot and Stephane Len, both researchers at the IRMES (Institut de Recherche bioMédicale et d'Epidemiologie du Sport at INSEP, Paris, France), have published their findings in Age, the official journal of the American Aging Association, describing the evolution of performances in elite athletes and chess grandmasters. This article is congruous with the epidemiological approaches developed by the laboratory, and suggests that changes in individual performance are linked to physiological laws structuring the living world.

A study published by the University of Reading's Centre for Agri Environmental Research suggests that honeybees may not be as important to pollination services in the UK than previously supposed. The research was published in the Journal Agriculture, Ecosystems and Environment.

Winning margins in the Tour de France can be tight – last year just 39 seconds separated the top two riders after more than 90 hours in the saddle. When every second counts, riders do everything possible to gain a competitive advantage – from using aerodynamic carbon fibre bikes to the very latest in sports nutrition.

Now there could be a new, completely legal and rather surprising weapon in the armoury for riders aiming to shave vital seconds off their time – beetroot juice.

A musculoskeletal system so far unknown in the animal world was recently discovered in weevils. The hip of Trigonopterus oblongus does not consist of the usual hinges, but of joints based on a screw-and-nut system. This first biological screw thread is about half a millimeter in size and was studied in detail using synchrotron radiation. The discovery is reported by the current issue of the Science magazine. (DOI:10.1126/science.1204245)

Viruses are the most abundant parasites on Earth. Well known viruses, such as the flu virus, attack human hosts, while viruses such as the tobacco mosaic virus infect plant hosts.

More common, but less understood, are cases of viruses infecting bacteria known as bacteriophages, or phages. In part, this is due to the difficulty of culturing bacteria and viruses that have been cut off from their usual biological surroundings in a process called in vitro.