Researchers at the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, identified for the first time the key role specific microRNAs (miRNAs) play in melanoma metastasis to simultaneously cause cancer cells to invade and immunosuppress the human body's ability to fight abnormal cells. The new study is published in the July 11, 2011 issue of the journal Cancer Cell.
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Researchers from Rigshospitalet – Copenhagen University Hospital – and the University of Copenhagen have discovered why malaria parasites are able to hide from the immune defences of expectant mothers, allowing the parasite to attack the placenta. The discovery is an important part of the efforts researchers are making to understand this frequently fatal disease and to develop a vaccine.
Genetic instructions for developing limbs and digits were present in primitive fish millions of years before their descendants first crawled on to land, researchers have discovered.
One in 10 species could face extinction by the year 2100 if current climate change impacts continue. This is the result of University of Exeter research, examining studies on the effects of recent climate change on plant and animal species and comparing this with predictions of future declines.
Cancer is not invincible but its weaknesses can be difficult to detect. An effort known as Project Achilles — named after the Greek warrior whose one vulnerability led to his undoing — was launched to develop a systematic way of pinpointing these weak spots. In their largest and most comprehensive effort to date, researchers from the Broad Institute of MIT and Harvard and the Dana-Farber Cancer Institute examined cells from over 100 tumors, including 25 ovarian cancer tumors, to unearth the genes upon which cancers depend.
Hospitals across the nation are increasingly implementing palliative care programs to help patients manage the physical and emotional burdens of serious illnesses, but a new University of Georgia study finds that 82 percent of the state's hospitals do not offer palliative care services.
Data revealing migrations of larval reef fish vital for designing networks of marine protected areas
Networks of biologically-connected marine protected areas need to be carefully planned, taking into account the open ocean migrations of marine fish larvae that take them from one home to another sometimes hundreds of kilometers away.
Research published today in the international journal Oecologia sheds new light on the dispersal of marine fish in their larval stages, important information for the effective design of marine protected areas (MPAs), a widely advocated conservation tool.
ANN ARBOR, Mich.---A link between chemicals called phthalates and thyroid hormone levels was confirmed by the University of Michigan in the first large-scale and nationally representative study of phthalates and BPA in relation to thyroid function in humans.
The U-M School of Public Health study also reported suggestive findings consistent with a previously reported link between a chemical called bisphenol-A and thyroid hormone levels. BPA is best known for its use in certain plastic water bottles and in the linings of canned foods.
CINCINNATI—The alarm caused by bisphenol A (BPA) presence in reusable plastic bottles resulted in a recent industry change, producing products made with supposed BPA-free materials.
Prompted by requests and concern from consumers, University of Cincinnati (UC) researchers wanted to see if these alternatives—including products made with stainless steel and coated aluminum—were truly giving the consumer an option free of BPA.
Current alcohol consumption guidelines are inadequate for the prevention of cancer and new international guidelines are needed, states an analysis in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj110363.pdf.
Several chemicals that can accumulate to high levels in our body (for example BPA and some pesticides) have been recently linked to an increased risk of cancer and/or impaired responsiveness to anticancer drugs. A team of researchers, led by Sridhar Mani, at Albert Einstein College of Medicine, New York, has now identified a potential mechanistic link between environmental exposure to these foreign chemicals (xenogens) and cancer drug therapy response and survival.
A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology (www.jcb.org).
BOSTON ––– Although it sounds like a case of gender confusion on a molecular scale, the male hormone androgen spurs the growth of some breast tumors in women. In a new study, scientists at Dana-Farber Cancer Institute provide the first details of the cancer cell machinery that carries out the hormone's relentless growth orders.
A difficult-to-treat form of childhood leukemia relies on changes in the structure of DNA – so-called epigenetic changes – to wreak genomic havoc within white blood cells, according to one of two studies conducted by a research team at Children's Hospital Boston and Dana-Farber Cancer Institute. Together with collaborators from a biotechnology company, the same team also showed that a new drug that blocks these changes could deactivate cancer-promoting genes and halt the growth of this cancer.
Online consumers thought to be motivated primarily by savings are, in fact, often willing to pay a premium for purchases from online vendors with clear, protective privacy policies, according to a new study in the current issue of a journal of the Institute for Operations Research and the Management Sciences (INFORMS®).