Scientists have confirmed the feasibility of using a new drug delivery system — the basis for a battery-powered skin patch — to administer medication that shows promise for treating peripheral artery disease (PAD) and healing stubborn skin ulcers and burns. The needle-free delivery of the medication, which cannot be given by mouth and can have side effects when injected, is reported in the ACS journal, Molecular Pharmaceutics.
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Gram for gram, novel carbon nanofiber-filled coatings devised by researchers from the National Institute of Standards and Technology (NIST) and Texas A&M University outperformed conventional flame retardants used in the polyurethane foam of upholstered furniture and mattresses by at least 160 percent and perhaps by as much as 1,130 percent.
DNA, a molecule famous for storing the genetic blueprints for all living things, can do other things as well. In a new paper,* researchers at the National Institute of Standards and Technology (NIST) describe how tailored single strands of DNA can be used to purify the highly desired "armchair" form of carbon nanotubes. Armchair-form single wall carbon nanotubes are needed to make "quantum wires" for low-loss, long distance electricity transmission and wiring.
Research led by the Warwick Crop Centre in the School of Life Sciences at the University of Warwick has developed a unique collection of information about the disease resistance of 96 of the world's onion varieties. It will be a crucial resource for commercial growers and seed producers trying to combat one of the most difficult diseases affecting onion crops. This work may also have benefits in terms of and reduced fertiliser consumption and enhanced drought tolerance.
Measuring the levels of a natural body chemical may allow doctors to reduce the duration of antibiotic use and improve the health outcomes of critically ill patients.
"Infection is a common and expensive complication of critical illness and we're trying to find ways to improve the outcomes of sick, elderly patients and, at the same time, reduce health care costs," says Daren Heyland, a professor of Medicine at Queen's, director of the Clinical Evaluation Research Unit at Kingston General Hospital, and scientific director of the Technology Evaluation in the Elderly Network.
New Rochelle, NY, August 3, 2011—Positive activity interventions (PAIs) offer a safe, low-cost, and self-administered approach to managing depression and may offer hope to individuals with depressive disorders who do not respond or have access to adequate medical therapy, according to a comprehensive review article in The Journal of Alternative and Complementary Medicine, a peer-reviewed journal published by Mary Ann Liebert, Inc.
When we make plans that will change a natural environment — whether it's building a new shopping mall or planting a new forest — surveyors dutifully assess the environmental risks to plant and animal life in the region. But what's environmentally good for one area may be an environmental disaster for an adjacent one, a Tel Aviv University researcher cautions.
Rising carbon dioxide (CO2) levels can reverse the drying effects of predicted higher temperatures on semi-arid rangelands, according to a study published today in the scientific journal Nature by a team of U.S. Department of Agriculture (USDA) and university scientists.
JACKSONVILLE, Fla. — A Mayo Clinic orthopedic surgeon suspects that the nagging pain and inflammation that women can experience in their knees may be different from what men encounter, and she has been chosen to lead a novel U.S.-Canadian study to explore the question.
Arriving at a rapid and accurate diagnosis is critical during flu outbreaks, but until now, physicians and public health officials have had to choose between a highly accurate yet time-consuming test or a rapid but error-prone test.
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A new study has identified the recent emergence of a multidrug-resistant strain of Salmonella that has a high level resistance to ciprofloxacin, a common treatment for severe Salmonella infections. The study, led by François-Xavier Weill, MD, and Simon Le Hello, PharmD, at the Pasteur Institute in France, is published in The Journal of Infectious Diseases and is now available online.
They make up less than one-hundredth of 1 percent of the microbes that live in the colon, but the bacteria and archaea that sop up hydrogen in the gut are fundamental to colon health. In a new study, researchers take a first look at these "hydrogenotrophic" microbes, mapping where they live and how abundant they are in different parts of the lower intestine.
The findings are reported in the International Society for Microbial Ecology Journal.
The immunochemical fecal occult blood test (iFOBT) is effective for predicting lesions in the lower intestine but not in the upper gastrointestinal (GI) tract, confirms a study in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj101248.pdf.
There is a reason exercise becomes more difficult with age. A report in the August Cell Metabolism, a Cell Press publication, ties the weakness of aging to leaky calcium channels inside muscle cells. But there is some good news: the researchers say a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks.
Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy.
(NEW YORK, NY, (August 2, 2011) – Researchers at Columbia University Medical Center have discovered the biological mechanism behind age-related loss of muscle strength and identified a drug that may help reverse this process. Their findings were published in the August 2 online edition of Cell Metabolism.