A research team has identified a potential new target for treatment of the childhood eye tumor retinoblastoma and they say their work also settles a scientific debate by showing the cancer's cellular origins are as scrambled as the developmental pathways at work in the tumor.
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A compound found in green tea shows great promise for the development of drugs to treat two types of tumors and a deadly congenital disease. The discovery is the result of research led by Principal Investigator, Dr. Thomas Smith at The Donald Danforth Plant Science Center and his colleagues at The Children's Hospital of Philadelphia.
A new prostate screening test developed by AnalizaDx, Inc., a Cleveland-based biotech company, and studied by researchers at the Seidman Cancer Center at University Hospitals (UH) Case Medical Center along with colleagues at the Cleveland Clinic, the Veterans Administration Boston Healthcare and the National Cancer Institute, may prove to be a promising new tool in the diagnosis of prostate cancer. The study in Urology found that this new screening test, the PSA/SIA assay, may be more sensitive in detecting prostate cancer than traditional screening methods.
Scientists at the Gladstone Institutes have gained new insight into the delicate relationship between two proteins that, when out of balance, can prevent the normal development of stem cells in the heart and may also be important in some types of cancer.
A study conducted by Hebrew University researchers has found that that there can be very short latency periods between the time of exposure and development of cancer in workers in tasks with intense or prolonged exposure to electro-magnetic fields (EMFs). Previous studies have described excess risks for cancer from such high occupational exposures. However, none have addressed the issue of short latency periods from high exposure.
Here's good news if you are eating a donut while reading this: Being fat can actually be good for you. Or at least not bad
A new study in Applied Physiology, Nutrition and Metabolism finds that obese people who are otherwise healthy live just as long as their slim counterparts, and are less likely to die of cardiovascular causes.
A new study in the Journal of Occupational and Environmental Hygiene details the hazards of lead battery manufacturing and recycling operations in emerging markets. Children living near these facilities in developing countries had approximately 13 times more lead in their blood than American children.
A pandemic of ailments sometimes called the 'allergic march' and referring to the gradual acquisition of overlapping allergic diseases that commonly begins in early childhood has frustrated both parents and physicians. For the last three decades, an explosion of eczema, food allergies, hay fever, and asthma have afflicted children in the United States, the European Union, and many other countries.
The mystery of how a butterfly has changed its wing patterns to mimic neighboring species and avoid being eaten by birds has been solved by a team of European scientists.
The greatest evolutionary thinkers have all wondered how butterflies that taste bad to birds have evolved the same patterns of warning coloration. Now, researchers led by the CNRS (Muséum National d'Histoire Naturelle, Paris) and the University of Exeter (UK) have shown how butterflies perform this amazing trick, known as 'Müllerian mimicry'.
In a new study, Sanford-Burnham scientists show that dietary fats interfere with an enzyme called GnT-4a glycosyltransferase, which is required for proper retention of glucose transporters in pancreatic beta cell membranes. Without functioning GnT-4a, clinical signs of diabetes emerged in mice fed a high-fat diet. The team is now considering methods to augment the enzyme's activity in humans, as a means to prevent or treat type 2 diabetes.
For human embryonic stem cell research to make it to prime time in therapy, it takes more than laboratory tissue cultures. Within batches of newly generated cells lurks a big potential problem: Any remaining embryonic stem cells, those that haven't differentiated into the desired tissue, can go on to become dangerous tumors called teratomas when transplanted into patients.
A laboratory mouse model that develops signs of the paralyzing disease amyotrophic lateral sclerosis (ALS) as they age has been important in research of Lou Gehrig's Disease but a new study in Nature Biotechnology, highlights investigators at Nationwide Children's Hospital who have developed a new model of ALS, one that mimics sporadic ALS, which represents about 90 percent of all cases.
Prostate cancer that has become resistant to hormone treatment and that does not respond to radiation or chemotherapy requires new methods of treatment. By attacking stem cell-like cells in prostate cancer, researchers at Lund University are working on a project to develop a new treatment option.
Increasing public awareness of the childhood obesity epidemic may be contributing to evidence of overall reductions in body mass index, a measure of obesity in children, according to the results of a nationwide study presented in Childhood Obesity, a peer-reviewed journal published by Mary Ann Liebert Inc.
A new study published in the American Journal of Industrial Medicine reveals that the WTC attacks affected the health of the New York City Fire Department (FDNY) resulting in more post-9/11 retirements than expected.
Led by David J. Prezant, MD, Chief Medical Officer, FDNY, researchers assessed a total of 7,763 retired firefighters between September 11, 1994, and September 10, 2008, comparing the total number of retirements and the number and proportion of accidental disability retirements 7 years before and 7 years after the WTC attack.